Nuclear Cardiology in 2023

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Sharmila Dorbala, MD, MPH, MASNC, FACC, Editor

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Piotr Slomka, PhD, MASNC, FACC, Editor

Nuclear Cardiology techniques have become essential for the evaluation and management of various cardiovascular diseases. Recent advancements in imaging technologies, such as hybrid PET/CT and PET/MR scanners, new image reconstruction software, and repurposing of existing radionuclide tracers, have enabled personalized therapies. In this issue of Cardiology Clinics on Nuclear Cardiology, experts discuss technological advancements and radiotracer developments that have revolutionized the field and enabled comprehensive evaluation and image-guided management of cardiovascular diseases.

The authors cover the use of single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) radiotracers and their use for risk stratification. They discuss the emerging technological SPECT-MPI advancements that make low-radiation dose and myocardial blood flow quantification possible. The value of coronary artery calcification to the MPI is also highlighted. In addition, the authors discuss various molecular imaging tracers, including 99mTc-pyrophosphate and 18F-sodium fluoride, which have been repurposed for cardiac imaging. These hot-spot tracers measure disease activity and aid in the personalized evaluation and management of cardiac amyloidosis, coronary disease, and aortic valve disease. Furthermore, the authors discuss the rapidly emerging role of 18F-Fluorodeoxyglucose–PET/CT in the management of patients with various inflammatory cardiovascular diseases, including cardiac sarcoidosis, vasculitis, and infective endocarditis. This includes its use for prosthetic valve and cardiac implantable electronic device evaluations. These advancements in nuclear cardiology offer a comprehensive evaluation of cardiovascular diseases, including the heart-brain connection. This systems-based approach can improve our understanding of how cardiovascular disease impacts an individual’s overall well-being and health.

We thank Dr Audrey H. Wu for the opportunity to edit this issue on Nuclear Cardiology. It has been a great pleasure to work with each of the authors; we thank them for their insightful contributions. Our special thanks to Karen Justine S. Dino Solomon and her team for their support and guidance throughout this issue.

Article infoIdentification

DOI: https://doi.org/10.1016/j.ccl.2023.03.001

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© 2023 Published by Elsevier Inc.

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