Lipin2 ameliorates diabetic encephalopathy via suppressing JNK/ERK-mediated NLRP3 inflammasome overactivation

Keywords

Diabetic encephalopathy

Lipin2

NLRP3 inflammasome

JNK/ERK signaling pathway

AbbreviationsBDNF

brain derived neurotrophic factor

DE

Diabetic encephalopathy

GAPDH

Glyceraldehyde-3-phosphate dehydrogenase

MAPK

Mitogen-activated protein kinase

MAP2

Microtubule associated protein 2

NLRP3

Nucleotide-binding oligomerization domain-like receptor protein 3

p-ERK

Phosphorylation of extracellular signal-regulated protein kinases 1/2

p-JNK

Phosphorylation of c-Jun amino terminal kinase

PSD-95

Postsynaptic density protein 95

qRT-PCR

Quantitative Real-Time Polymerase Chain Reaction

Data availability

Data will be made available on request.

© 2023 Published by Elsevier B.V.

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