Emara, A. & Shah, R. Recent update on craniofacial tissue engineering. J. Tissue Eng. 12, 20417314211003735 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Disease, G. B. D., Injury, I. & Prevalence, C. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 392, 1789–1858 (2018).

Article  Google Scholar 

Abusleme, L. et al. The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation. ISME J. 7, 1016–1025 (2013).

Article  PubMed  PubMed Central  Google Scholar 

Peres, M. A. et al. Oral diseases: a global public health challenge. Lancet 394, 249–260 (2019).

Article  PubMed  Google Scholar 

Chen, M. X., Zhong, Y. J., Dong, Q. Q., Wong, H. M. & Wen, Y. F. Global, regional, and national burden of severe periodontitis, 1990–2019: an analysis of the Global Burden of Disease Study 2019. J. Clin. Periodontol. 48, 1165–1188 (2021).

Article  PubMed  Google Scholar 

Page, R. C. & Kornman, K. S. The pathogenesis of human periodontitis: an introduction. Periodontol 2000 14, 9–11 (1997).

Article  PubMed  Google Scholar 

Schwarz, F., Derks, J., Monje, A. & Wang, H. L. Peri-implantitis. J. Periodontol. 89(Suppl 1), S267–S290 (2018).

Article  PubMed  Google Scholar 

Dreyer, H. et al. Epidemiology and risk factors of peri-implantitis: a systematic review. J. Periodontal. Res. 53, 657–681 (2018).

Article  PubMed  Google Scholar 

Chen, Z., Wang, Z., Qiu, W. & Fang, F. Overview of antibacterial strategies of dental implant materials for the prevention of peri-implantitis. Bioconjug. Chem. 32, 627–638 (2021).

Article  PubMed  Google Scholar 

Monje, A., Vera, M., Munoz-Sanz, A., Wang, H. L. & Nart, J. Suppuration as diagnostic criterium of peri-implantitis. J. Periodontol. 92, 216–224 (2021).

Article  PubMed  Google Scholar 

Romandini, M. et al. Prevalence and risk/protective indicators of peri-implant diseases: A university-representative cross-sectional study. Clin. Oral. Implants Res. 32, 112–122 (2021).

Article  PubMed  Google Scholar 

Dewan, M. C. et al. Estimating the global incidence of traumatic brain injury. J. Neurosurg. https://doi.org/10.3171/2017.10.JNS17352 (2018).

Diseases, G. B. D. & Injuries, C. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet 396, 1204–1222 (2020).

Article  Google Scholar 

Jiang, J. Y. et al. Traumatic brain injury in China. Lancet Neurol. 18, 286–295 (2019).

Article  PubMed  Google Scholar 

Maas, A. I. R. et al. Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. Lancet Neurol. 16, 987–1048 (2017).

Article  PubMed  Google Scholar 

Figueiredo, C. P., Teixeira, H. M., Afonso, A. S. & Corte-Real, A. Prevalence of, and disability approaches to, temporomandibular joint trauma: a 17-year cross-sectional study. Dent. Traumatol. 36, 624–631 (2020).

Article  PubMed  Google Scholar 

Cheong, Y. W. & Lo, L. J. Facial asymmetry: etiology, evaluation, and management. Chang Gung Med. J. 34, 341–351 (2011).

PubMed  Google Scholar 

Giraddi, G. B., Arora, K. & Sai Anusha, A. J. Distraction osteogenesis in the treatment of temporomandibular joint ankylosis with mandibular micrognathia. Ann. Maxillofac. Surg. 6, 68–74 (2016).

Article  PubMed  PubMed Central  Google Scholar 

Kawecki, F., Clafshenkel, W. P., Fortin, M., Auger, F. A. & Fradette, J. Biomimetic tissue-engineered bone substitutes for maxillofacial and craniofacial repair: the potential of cell sheet technologies. Adv. Health. Mater. 7, e1700919 (2018).

Article  Google Scholar 

Johnson, D. E. et al. Head and neck squamous cell carcinoma. Nat. Rev. Dis. Prim. 6, 92 (2020).

Article  PubMed  Google Scholar 

Ferlay, J. et al. Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods. Int. J. Cancer 144, 1941–1953 (2019).

Article  PubMed  Google Scholar 

Bray, F. et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 68, 394–424 (2018).

Article  PubMed  Google Scholar 

Menezes, F. D. S., Fernandes, G. A., Antunes, J. L. F., Villa, L. L. & Toporcov, T. N. Global incidence trends in head and neck cancer for HPV-related and -unrelated subsites: A systematic review of population-based studies. Oral Oncol. 115, 105177 (2021).

Article  PubMed  Google Scholar 

Stein, A. P. et al. Prevalence of human papillomavirus in oropharyngeal cancer: a systematic review. Cancer J. 21, 138–146 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Latimer, J. M. et al. Regenerative medicine technologies to treat dental, oral, and craniofacial defects. Front. Bioeng. Biotechnol. 9, 704048 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Zhang, Y., Gulati, K., Li, Z., Di, P. & Liu, Y. Dental implant nano-engineering: advances, limitations and future directions. Nanomaterials 11, 2489 (2021).

Rinkel, R. N. et al. Prevalence of swallowing and speech problems in daily life after chemoradiation for head and neck cancer based on cut-off scores of the patient-reported outcome measures SWAL-QOL and SHI. Eur. Arch. Otorhinolaryngol. 273, 1849–1855 (2016).

Article  PubMed  Google Scholar 

Kraaijenga, S. A. et al. Assessment of voice, speech, and related quality of life in advanced head and neck cancer patients 10-years+ after chemoradiotherapy. Oral Oncol. 55, 24–30 (2016).

Article  PubMed  Google Scholar 

Mossey, P. A., Little, J., Munger, R. G., Dixon, M. J. & Shaw, W. C. Cleft lip and palate. Lancet 374, 1773–1785 (2009).

Article  PubMed  Google Scholar 

Timberlake, A. T. et al. Haploinsufficiency of SF3B2 causes craniofacial microsomia. Nat. Commun. 12, 4680 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Ross, M. T. et al. Aesthetic reconstruction of microtia: a review of current techniques and new 3D printing approaches. Virtual Phys. Prototyp. 13, 117–130 (2018).

Article  Google Scholar 

Wilkie, A. O. & Morriss-Kay, G. M. Genetics of craniofacial development and malformation. Nat. Rev. Genet. 2, 458–468 (2001).

Article  PubMed  Google Scholar 

Teven, C. M., Fisher, S., Ameer, G. A., He, T. C. & Reid, R. R. Biomimetic approaches to complex craniofacial defects. Ann. Maxillofac. Surg. 5, 4–13 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Ward, B. B., Brown, S. E. & Krebsbach, P. H. Bioengineering strategies for regeneration of craniofacial bone: a review of emerging technologies. Oral. Dis. 16, 709–716 (2010).

Article  PubMed  Google Scholar 

Kalluri, L. & Duan, Y. in Advances in Dental Implantology using Nanomaterials and Allied Technology Applications (eds R. S. Chaughule & R. Dashaputra) p. 137-152 (Springer International Publishing, 2021).

Wang, X. et al. Restoration of a critical mandibular bone defect using human alveolar bone-derived stem cells and porous nano-HA/collagen/PLA scaffold. Stem Cells Int. 2016, 8741641 (2016).

Article  PubMed  PubMed Central  Google Scholar 

Jakoi, A. M., Iorio, J. A. & Cahill, P. J. Autologous bone graft harvesting: a review of grafts and surgical techniques. Musculoskelet. Surg. 99, 171–178 (2015).

Article  PubMed  Google Scholar 

Thimmappa, B. & Girod, S. C. Principles of implant-based reconstruction and rehabilitation of craniofacial defects. Craniomaxillofac. Trauma Reconstr. 3, 33–40 (2010).

Article  PubMed  PubMed Central  Google Scholar 

Berglundh, T., Persson, L. & Klinge, B. A systematic review of the incidence of biological and technical complications in implant dentistry reported in prospective longitudinal studies of at least 5 years. J. Clin. Periodontol. 29(Suppl 3), 197–212 (2002).

Article  PubMed  Google Scholar 

Elani, H. W., Starr, J. R., Da Silva, J. D. & Gallucci, G. O. Trends in dental implant use in the U.S., 1999–2016, and projections to 2026. J. Dent. Res. 97, 1424–1430 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Kolk, A. et al. Current trends and future perspectives of bone substitute materials - from space holders to innovative biomaterials. J. Craniomaxillofac Surg. 40, 706–718 (2012).

Article  PubMed  Google Scholar 

Zhu, M. et al. The synergy of topographical micropatterning and Ta|TaCu bilayered thin film on titanium implants enables dual-functions of enhanced osteogenesis and anti-infection. Adv. Healthc. Mater. 10, e2002020 (2021).

Article  PubMed  Google Scholar 

Li, J. et al. Balancing bacteria-osteoblast competition through selective physical puncture and biofunctionalization of ZnO/polydopamine/arginine-glycine-aspartic acid-cysteine nanorods. ACS Nano 11, 11250–11263 (2017).

Article  PubMed  Google Scholar 

Sumner, D. R. & Galante, J. O. Determinants of stress shielding: design versus materials versus interface. Clin. Orthop. Relat. Res. 202–212 (1992).

Subbiahdoss, G., Kuijer, R., Grijpma, D. W., van der Mei, H. C. & Busscher, H. J. Microbial biofilm growth vs. tissue integration: “the race for the surface” experimentally studied. Acta Biomater. 5, 1399–1404 (2009).

Article