Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-19

WHO, Pneumonia of unknown cause—China. WHO. World Health Organization. 2020. http://www.who.int/csr/don/05-january-2020-pneumonia-of-unkown-cause-china/en/. Accessed 10 Nov 2020.

Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727–33.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang J, Petitjean SJL, Koehler M, Zhang Q, Dumitru AC, Chen W, et al. Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor. Nat Commun. 2020;11(1):4541.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Farahani M, Niknam Z, Mohammadi Amirabad L, Amiri-Dashatan N, Koushki M, Nemati M, et al. Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets. Biomed Pharmacother. 2022;1(145): 112420.

Article  Google Scholar 

Filchakova O, Dossym D, Ilyas A, Kuanysheva T, Abdizhamil A, Bukasov R. Review of COVID-19 testing and diagnostic methods. Talanta. 2022;1(244): 123409.

Article  Google Scholar 

Almstrand AC, Bake B, Ljungström E, Larsson P, Bredberg A, Mirgorodskaya E, et al. Effect of airway opening on production of exhaled particles. J Appl Physiol. 2010;108(3):584–8.

Article  PubMed  Google Scholar 

Carvalho AS, Matthiesen R. Bronchoalveolar lavage: quantitative mass spectrometry-based proteomics analysis in lung diseases. Methods Mol Biol. 2017;1619:487–94.

Article  CAS  PubMed  Google Scholar 

Wang S, Yao X, Ma S, Ping Y, Fan Y, Sun S, et al. A single-cell transcriptomic landscape of the lungs of patients with COVID-19. Nat Cell Biol. 2021;23(12):1314–28.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shen B, Yi X, Sun Y, Bi X, Du J, Zhang C, et al. Proteomic and metabolomic characterization of COVID-19 patient Sera. Cell. 2020;182(1):59-72.e15.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zeng HL, Chen D, Yan J, Yang Q, Han QQ, Li SS, et al. Proteomic characteristics of bronchoalveolar lavage fluid in critical COVID-19 patients. FEBS J. 2021;288(17):5190–200.

Article  CAS  PubMed  Google Scholar 

Liu JF, Zhou YN, Lu SY, Yang YH, Wu SF, Liu DP, et al. Proteomic and phosphoproteomic profiling of COVID-19-associated lung and liver injury: a report based on rhesus macaques. Signal Transduct Target Ther. 2022;7(1):27.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Broberg E, Andreasson J, Fakhro M, Olin AC, Wagner D, Hyllén S, et al. Mechanically ventilated patients exhibit decreased particle flow in exhaled breath as compared to normal breathing patients. ERJ Open Res. 2020;6(1):00198–2019.

Article  PubMed  PubMed Central  Google Scholar 

Tyanova S, Temu T, Cox J. The MaxQuant computational platform for mass spectrometry-based shotgun proteomics. Nat Protoc. 2016;11(12):2301–19.

Article  CAS  PubMed  Google Scholar 

Willforss J, Chawade A, Levander F. NormalyzerDE: online tool for improved normalization of omics expression data and high-sensitivity differential expression analysis. J Proteome Res. 2019;18(2):732–40.

Article  CAS  PubMed  Google Scholar 

Zhu L, Malatras A, Thorley M, Aghoghogbe I, Mer A, Duguez S, et al. Cell Where: graphical display of interaction networks organized on subcellular localizations. Nucleic Acids Res. 2015;43(W1):W571-575.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lacombe M, Marie-Desvergne C, Combes F, Kraut A, Bruley C, Vandenbrouck Y, et al. Proteomic characterization of human exhaled breath condensate. J Breath Res. 2018;12(2): 021001.

Article  PubMed  Google Scholar 

Muccilli V, Saletti R, Cunsolo V, Ho J, Gili E, Conte E, et al. Protein profile of exhaled breath condensate determined by high resolution mass spectrometry. J Pharm Biomed Anal. 2015;25(105):134–49.

Article  Google Scholar 

Stenlo M, Hyllén S, Silva IAN, Bölükbas DA, Pierre L, Hallgren O, et al. Increased particle flow rate from airways precedes clinical signs of ARDS in a porcine model of LPS-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2020;318(3):L510–7.

Article  PubMed  PubMed Central  Google Scholar 

Viklund E, Kokelj S, Larsson P, Nordén R, Andersson M, Beck O, et al. Severe acute respiratory syndrome coronavirus 2 can be detected in exhaled aerosol sampled during a few minutes of breathing or coughing. Influenza Other Respir Viruses. 2022;16(3):402–10.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ihling C, Tänzler D, Hagemann S, Kehlen A, Hüttelmaier S, Arlt C, et al. Mass spectrometric identification of SARS-CoV-2 proteins from gargle solution samples of COVID-19 patients. J Proteome Res. 2020;19(11):4389–92.

Article  CAS  PubMed  Google Scholar 

Zakharova N, Kozyr A, Ryabokon AM, Indeykina M, Strelnikova P, Bugrova A, et al. Mass spectrometry based proteome profiling of the exhaled breath condensate for lung cancer biomarkers search. Expert Rev Proteomics. 2021;18(8):637–42.

Article  CAS  PubMed  Google Scholar 

Stenlo M, Silva IAN, Hyllén S, Bölükbas DA, Niroomand A, Grins E, et al. Monitoring lung injury with particle flow rate in LPS- and COVID-19-induced ARDS. Physiol Rep. 2021;9(13): e14802.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Edwards DA, Ausiello D, Salzman J, Devlin T, Langer R, Beddingfield BJ, et al. Exhaled aerosol increases with COVID-19 infection, age, and obesity. Proc Natl Acad Sci. 2021;118(8): e2021830118.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Edwards DA, Man JC, Brand P, Katstra JP, Sommerer K, Stone HA, et al. Inhaling to mitigate exhaled bioaerosols. Proc Natl Acad Sci USA. 2004;101(50):17383–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hallgren F, Stenlo M, Niroomand A, Broberg E, Hyllén S, Malmsjö M, et al. Particle flow rate from the airways as fingerprint diagnostics in mechanical ventilation in the intensive care unit: a randomised controlled study. ERJ Open Res. 2021;7(3):00961–2020.

Article  PubMed  PubMed Central  Google Scholar 

Broberg E, Wlosinska M, Algotsson L, Olin AC, Wagner D, Pierre L, et al. A new way of monitoring mechanical ventilation by measurement of particle flow from the airways using Pexa method in vivo and during ex vivo lung perfusion in DCD lung transplantation. Intensive Care Med Exp. 2018;6(1):18.

Article  PubMed  PubMed Central  Google Scholar 

Shu T, Ning W, Wu D, Xu J, Han Q, Huang M, et al. Plasma proteomics identify biomarkers and pathogenesis of COVID-19. Immunity. 2020. https://doi.org/10.1016/j.immuni.2020.10.008.

Article  PubMed  PubMed Central  Google Scholar 

Crestani B, Rolland C, Lardeux B, Fournier T, Bernuau D, Poüs C, et al. Inducible expression of the alpha1-acid glycoprotein by rat and human type II alveolar epithelial cells. J Immunol. 1998;160(9):4596–605.

Article  CAS  PubMed  Google Scholar 

Hamid EA, Ali W, Ahmed H, Megawer A, Osman W. Significance of acute phase reactants as prognostic biomarkers for pneumonia in children. Biomed Pharmacol J. 2021;14(3):1309–21.

Article  Google Scholar 

Gordon SM, Hofmann S, Askew DS, Davidson WS. High density lipoprotein: it’s not just about lipid transport anymore. Trends Endocrinol Metab TEM. 2011;22(1):9–15.

Article  CAS  PubMed  Google Scholar 

Georgila K, Vyrla D, Drakos E. Apolipoprotein A-I (ApoA-I), immunity, inflammation and cancer. Cancers. 2019;11(8):E1097.

Article  Google Scholar 

Catapano AL, Pirillo A, Bonacina F, Norata GD. HDL in innate and adaptive immunity. Cardiovasc Res. 2014;103(3):372–83.

Article  CAS  PubMed  Google Scholar 

Lee EH, Lee EJ, Kim HJ, Jang AS, Koh ES, Uh ST, et al. Overexpression of apolipoprotein A1 in the lung abrogates fibrosis in experimental silicosis. PloS ONE. 2013;8(2): e55827.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schmelter F, Föh B, Mallagaray A, Rahmöller J, Ehlers M, Lehrian S, et al. Metabolic and lipidomic markers differentiate COVID-19 from non-hospitalized and other intensive care patients. Front Mol Biosci. 2021;8: 737039.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nukui Y, Miyazaki Y, Suhara K, Okamoto T, Furusawa H, Inase N. Identification of apolipoprotein A-I in BALF as a biomarker of sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2018;35(1):5–15.

PubMed  PubMed Central  Google Scholar 

Mehrani H, Ghanei M, Aslani J, Golmanesh L. Bronchoalveolar lavage fluid proteomic patterns of sulfur mustard-exposed patients. Proteomics Clin Appl. 2009;3(10):1191–200.

Article  CAS  PubMed 

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