Association between periodontitis and uric acid levels in blood and oral fluids: a systematic review and meta-analysis

Botelho J, Mascarenhas P, Viana J, Proença L, Orlandi M, Leira Y, et al. An umbrella review of the evidence linking oral health and systemic noncommunicable diseases. Nat Commun. 2022;13:7614.

Article  PubMed  PubMed Central  Google Scholar 

Hajishengallis G, Lamont RJ. Polymicrobial communities in periodontal disease: Their quasi-organismal nature and dialogue with the host. Periodontol. 2021;2000(86):210–30.

Article  Google Scholar 

Hajishengallis G, Chavakis T. Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities. Nat Rev Immunol. 2021;21:426–40.

Article  PubMed  PubMed Central  Google Scholar 

da Pereira Silva FR, Bentes Leal ALA, Koga RS, Pereira Alves EH, de Pinho Lira JAS, da Alves Silva H, et al. Relationship between the rs333 Polymorphism in the CC Chemokine Receptor Type Five (CCR5) gene and immunological disorders: data from a meta-analysis. Int J Stat Med Res. 2021;10:8596.

Google Scholar 

da Pereira Silva FR, Pessoa LDS, Shin JI, Alves EHP, Koga RS, Smith CV, et al. Polymorphisms in the interleukin genes and chronic periodontitis: A field synopsis and revaluation by Bayesian approaches. Cytokine. 2021;138:155361.

Article  Google Scholar 

Trindade D, Carvalho R, Machado V, Chambrone L, Mendes JJ, Botelho J. Prevalence of periodontitis in dentate people between 2011 and 2020: A systematic review and meta-analysis of epidemiological studies. J Clin Periodontol. 2023 Jan 11; https://doi.org/10.1111/jcpe.13769.

Botelho J, Machado V, Leira Y, Proença L, Chambrone L, Mendes JJ. Economic burden of periodontitis in the United States and Europe: An updated estimation. J Periodontol. 2022;93:373–9.

Article  PubMed  Google Scholar 

Hajishengallis G. Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response. Trends Immunol. 2014;35:3–11.

Article  PubMed  Google Scholar 

Chen ZY, Xu TT, Liang ZJ, Zhao L, Xiong XQ, Xie KK, et al. Untargeted and targeted gingival metabolome in rodents reveal metabolic links between high-fat diet-induced obesity and periodontitis. J Clin Periodontol. 2021;48(8):1137–48

Wang Y, Andrukhov O, Rausch-Fan X. Oxidative stress and antioxidant system in periodontitis. Front Physiol. 2017;8:910.

Article  PubMed  PubMed Central  Google Scholar 

Kumar J, Teoh SL, Das S, Mahakknaukrauh P. Oxidative stress in oral diseases: understanding its relation with other systemic diseases. Front Physiol. 2017;8:693.

Article  PubMed  PubMed Central  Google Scholar 

Lin K, Lu C, Hung K, Wu P, Pan C, Wu C, et al. The paradoxical role of uric acid in osteoporosis. Nutrients. 2019;11:2111.

Article  PubMed  PubMed Central  Google Scholar 

Ali N, Perveen R, Rahman S, Mahmood S, Rahman S, Islam S, et al. Prevalence of hyperuricemia and the relationship between serum uric acid and obesity: A study on Bangladeshi adults. PLoS ONE. 2018;13:e0206850.

Article  PubMed  PubMed Central  Google Scholar 

Cortese F, Giordano P, Scicchitano P, Faienza MF, De Pergola G, Calculli G, et al. Uric acid: from a biological advantage to a potential danger. A focus on cardiovascular effects. Vasc Pharmacol. 2019;120:106565.

Article  Google Scholar 

Li C, Hsieh M, Chang S. Metabolic syndrome, diabetes, and hyperuricemia. Curr Opin Rheumatol. 2013;25:210–6.

Article  PubMed  Google Scholar 

Santos CX, Anjos EI, Augusto O. Uric acid oxidation by peroxynitrite: multiple reactions, free radical formation, and amplification of lipid oxidation. Arch Biochem Biophys. 1999;372:285–94.

Article  PubMed  Google Scholar 

Vasquez-Vivar J, Santos AM, Junqueira VB, Augusto O. Peroxynitrite-mediated formation of free radicals in human plasma: EPR detection of ascorbyl, albumin-thiyl and uric acid-derived free radicals. Biochem J. 1996;314(Pt 3):869–76.

Article  PubMed  PubMed Central  Google Scholar 

Sautin YY, Johnson RJ. Uric acid: the oxidant-antioxidant paradox. Nucleosides Nucleotides Nucleic Acids. 2008;27:608–19.

Article  PubMed  PubMed Central  Google Scholar 

Sculley DV, Langley-Evans SC. Salivary antioxidants and periodontal disease status. Proc Nutr Soc. 2002;61:137–43.

Article  PubMed  Google Scholar 

Tóthová L, Kamodyová N, Červenka T, Celec P. Salivary markers of oxidative stress in oral diseases. Front Cell Infect Microbiol. 2015;20:5.

Google Scholar 

Cao YL, Qiao M, Xu ZH, Zou GM, Ma LL, Li WG, et al. The clinical study of IgA nephropathy with severe chronic periodontitis and aggressive periodontitis. Natl Med J China. 2016;96:9–13.

Google Scholar 

Tsai KZ, Su FY, Cheng WC, Huang RY, Lin YP, Lin GM. Associations between metabolic biomarkers and localized stage II/III periodontitis in young adults: The CHIEF Oral Health study. J Clin Periodontol. 2021;48:1549–58.

Article  PubMed  Google Scholar 

Nessa N, Kobara M, Toba H, Adachi T, Yamamoto T, Kanamura N, et al. Febuxostat attenuates the progression of periodontitis in rats. Pharmacology. 2021;106:294–304.

Article  PubMed  Google Scholar 

Sato K, Yamazaki K, Kato T, Nakanishi Y, Tsuzuno T, Yokoji-Takeuchi M, et al. Obesity-related gut microbiota aggravates alveolar bone destruction in experimental periodontitis through elevation of uric acid. mBio. 2021;12:e0077121.

Article  PubMed  Google Scholar 

Banu S, Jabir NR, Mohan R, Manjunath NC, Kamal MA, Kumar KRV, et al. Correlation of toll-like receptor 4, interleukin-18, transaminases, and uric acid in patients with chronic periodontitis and healthy adults. J Periodontol. 2015;86:431–9.

Article  PubMed  Google Scholar 

Gharbi A, Hamila A, Bouguezzi A, Dandana A, Ferchichi S, Chandad F, et al. Biochemical parameters and oxidative stress markers in Tunisian patients with periodontal disease. BMC Oral Health. 2019;19:225.

Article  PubMed  PubMed Central  Google Scholar 

Narendra S, Das UK, Tripathy SK, Sahani NC. Superoxide dismutase, uric acid, total antioxidant status, and lipid peroxidation assay in chronic and aggressive periodontitis patients. J Contemp Dent Pract. 2018;19:874–80.

Article  PubMed  Google Scholar 

Miricescu D, Totan A, Calenic B, Mocanu B, Didilescu A, Mohora M, et al. Salivary biomarkers: relationship between oxidative stress and alveolar bone loss in chronic periodontitis. Acta Odontol Scand. 2014;72:42–7.

Article  PubMed  Google Scholar 

Diab-Ladki R, Pellat B, Chahine R. Decrease in the total antioxidant activity of saliva in patients with periodontal diseases. Clin Oral Investig. 2003;7:103–7.

Article  PubMed  Google Scholar 

Barnes VM, Teles R, Trivedi HM, Devizio W, Xu T, Mitchell MW, et al. Acceleration of purine degradation by periodontal diseases. J Dent Res. 2009;88:851–5.

Article  PubMed  Google Scholar 

Chen ZY, Ye LW, Zhao L, Liang ZJ, Yu T, Gao J. Hyperuricemia as a potential plausible risk factor for periodontitis. Med Hypotheses. 2020;137:109591.

Article  PubMed  Google Scholar 

Byun SH, Yoo DM, Lee JW, Choi HG. Analyzing the association between hyperuricemia and periodontitis: A cross-sectional study using KoGES-HEXA data. Int J Environ Res Public Health. 2020;17:1–10.

Google Scholar 

Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the prisma statement. PLoS Med. 2009;6:e1000097.

Article  PubMed  PubMed Central  Google Scholar 

Tian S, Li J, Li R, Liu Z, Dong W. Decreased serum bilirubin levels and increased uric acid levels are associated with ulcerative colitis. Med Sci Monit. 2018;24:6298–304.

Article  PubMed  PubMed Central  Google Scholar 

Zhu F, Feng D, Zhang T, Gu L, Zhu W, Guo Z, et al. Altered uric acid metabolism in isolated colonic Crohn’s disease but not ulcerative colitis. J Gastroenterol Hepatol. 2019;34:154–61.

Article  PubMed  Google Scholar 

Ponvilawan B, Charoenngam N, Ungprasert P. Primary hyperparathyroidism is associated with a higher level of serum uric acid: A systematic review and meta-analysis. Int J Rheum Dis. 2020;23:174–80.

Article  PubMed  Google Scholar 

Charoenngam N, Ponvilawan B, Ungprasert P. Vitamin D insufficiency and deficiency are associated with a higher level of serum uric acid: A systematic review and meta-analysis. Mod Rheumatol. 2020;30:385–90.

Article  PubMed  Google Scholar 

Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA, editors. Cochrane Handbook for Systematic Reviews of Interventions. 2nd ed. Chichester (UK): John Wiley & Sons; 2019.

Google Scholar 

Su H, Ruan J, Chen T, Lin E, Shi L. CT-assessed sarcopenia is a predictive factor for both long-term and short-term outcomes in gastrointestinal oncology patients: a systematic review and meta-analysis. Cancer Imaging. 2019;19:82.

Article  PubMed  PubMed Central  Google Scholar 

Chen M, Cai W, Zhao S, Shi L, Chen Y, Li X, et al. Oxidative stress-related biomarkers in saliva and gingival crevicular fluid associated with chronic periodontitis: A systematic review and meta-analysis. J Clin Periodontol. 2019;46:608–22.

Article  PubMed  Google Scholar 

Balshem H, Helfand M, Schünemann HJ, Oxman AD, Kunz R, Brozek J, et al. GRADE guidelines: 3. Rating the quality of evidence. J Clin Epidemiol. 2011;64:401–6.

Article  PubMed  Google Scholar 

Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;26(336):924–6.

Article  Google Scholar 

Munther S. The effects of cigarette smoking and exercise on total salivary antioxidant activity. Saudi Dent J. 2019;31:31–8.

Article  PubMed  Google Scholar 

Yang T, Zhang Y, Wei J, Zeng C, Li LJ, Xie X, et al. Relationship between cigarette smoking and hyperuricemia in middle-aged and elderly population: a cross-sectional study. Rheumatol Int. 2017;37:131–6.

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