A prospective feasibility study of uracil–tegafur and leucovorin as adjuvant chemotherapy for patients aged ≥ 80 years after curative resection of colorectal cancer, the HiSCO-03 study

National Cancer Institute (2022) Surveillance, epidemiology, and end results program. https://seer.cancer.gov/statfacts/html/colorect.html. Accessed 29 Oct 2022

André T, Boni C, Mounedji-Boudiaf L, Navarro M, Tabernero J, Hickish T, Topham C, Zaninelli M, Clingan P, Bridgewater J et al (2004) Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med 350(23):2343–2351. https://doi.org/10.1056/NEJMoa032709

Article  PubMed  Google Scholar 

Kuebler JP, Wieand HS, O’Connell MJ, Smith RE, Colangelo LH, Yothers G, Petrelli NJ, Findlay MP, Seay TE, Atkins JN et al (2007) Oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: results from NSABP C-07. J Clin Oncol 25(16):2198–2204. https://doi.org/10.1200/JCO.2006.08.2974

Article  CAS  PubMed  Google Scholar 

Haller DG, O'Connell MJ, Cartwright TH, Twelves CJ, McKenna EF, Sun W, Saif MW, Lee S, Yothers G, Schmoll HJ (2015) Impact of age and medical comorbidity on adjuvant treatment outcomes for stage III colon cancer: a pooled analysis of individual patient data from four randomized, controlled trials. Ann Oncol 26(4):715–724. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374386

Tournigand C, Andre T, Bonnetain F, Chibaudel B, Lledo G, Hickish T, Tabernero J, Boni C, Bachet JB, Teixeira L et al (2012) Adjuvant therapy with fluorouracil and oxaliplatin in stage II and elderly patients (between ages 70 and 75 years) with colon cancer: subgroup analyses of the Multicenter International Study of Oxaliplatin, Fluorouracil, and Leucovorin in the Adjuvant Treatment of Colon Cancer trial. J Clin Oncol 30(27):3353–3360. https://doi.org/10.1200/JCO.2012.42.5645

Yothers G, O'Connell MJ, Allegra CJ, Kuebler JP, Colangelo LH, Petrelli NJ, Wolmark N (2011) Oxaliplatin as adjuvant therapy for colon cancer: updated results of NSABP C-07 trial, including survival and subset analyses. J Clin Oncol 29(28):3768–3774. https://doi.org/10.1200/JCO.2011.36.4539

Twelves C, Wong A, Nowacki MP, Abt M, Burris H III, Carrato A, Cassidy J, Cervantes A, Fagerberg J, Georgoulias V et al (2005) Capecitabine as adjuvant treatment for stage III colon cancer. N Engl J Med 352(26):2696–2704. https://doi.org/10.1056/NEJMoa043116

YoYoshida M, Ishiguro M, Ikejiri K, Mochizuki I, Nakamoto Y, Kinugasa Y, Takagane A, Endo T, Shinozaki H, Takii Y et al (2014) S-1 as adjuvant chemotherapy for stage III colon cancer: a randomized phase III study (ACTS-CC trial). Ann Oncol 25(9):1743–1749. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143094

Sadahiro S, Tsuchiya T, Sasaki K, Kondo K, Katsumata K, Nishimura G, Kakeji Y, Baba H, Sato S, Koda K et al (2015) Randomized phase III trial of treatment duration for oral uracil and tegafur plus leucovorin as adjuvant chemotherapy for patients with stage IIB/III colon cancer: final results of JFMC33-0502. Ann Oncol 26(11):2274–2280. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621030

Shimada Y, Hamaguchi T, Mizusawa J, Saito N, Kanemitsu Y, Takiguchi N, Ohue M, Kato T, Takii Y, Sato T et al (2014) Randomised phase III trial of adjuvant chemotherapy with oral uracil and tegafur plus leucovorin versus intravenous fluorouracil and levofolinate in patients with stage III colorectal cancer who have undergone Japanese D2/D3 lymph node dissection: final results of JCOG0205. Eur J Cancer 50(13):2231–2240. https://www.sciencedirect.com/science/article/pii/S0959804914007242

Shimomura M, Ikeda S, Nakahara M, Adachi T, Saitoh Y, Shimizu Y, Toyota K, Ishizaki Y, Yoshimitsu M, Takakura Y et al (2023) Prospective cohort study of patients with stage III colorectal cancer aged ≥ 80 years who underwent curative resection: the HiSCO-04 study. J Clin Oncol 41(Suppl 4: Abstr 1):26s

Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360123

World Health Organization (2022) The global health observatory. https://www.who.int/data/gho. Accessed 29 Oct 2022

Ministry of Health, Labour and Welfare (2022) Summary of the 2010 simplified life tables. https://www.mhlw.go.jp/toukei/saikin/hw/life/life10/01.html. Accessed 29 Oct 2022

Sargent DJ, Goldberg RM, Jacobson SD, Macdonald JS, Labianca R, Haller DG, Shepherd LE, Seitz JF, Francini G (2001) A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients. N Engl J Med 345(15):1091–1097. https://doi.org/10.1056/NEJMoa010957

Mochizuki I, Takiuchi H, Ikejiri K, Nakamoto Y, Kinugasa Y, Takagane A, Endo T, Shinozaki H, Takii Y, Takahashi Y et al (2012) Safety of UFT/LV and S-1 as adjuvant therapy for stage III colon cancer in phase III trial: ACTS-CC trial. Br J Cancer 106(7):1268–1273. https://www.nature.com/articles/bjc201286

Lembersky BC, Wieand HS, Petrelli NJ, O'Connell MJ, Colangelo LH, Smith RE, Seay TE, Giguere JK, Marshall ME, Jacobs AD et al (2006) Oral uracil and tegafur plus leucovorin compared with intravenous fluorouracil and leucovorin in stage II and III carcinoma of the colon: results from National Surgical Adjuvant Breast and Bowel Project Protocol C-06. J Clin Oncol 24(13):2059–2064. https://doi.org/10.1200/JCO.2005.04.7498

Ellis G, Whitehead MA, O'Neill D, Langhorne P, Robinson D (2011) Comprehensive geriatric assessment for older adults admitted to hospital. Cochrane Database Syst Rev (7):CD006211. https://www.bmj.com/content/343/bmj.d6553.long

Kalsi T, Babic-Illman G, Ross PJ, Maisey NR, Hughes S, Fields P, Martin FC, Wang Y, Harari D (2015) The impact of comprehensive geriatric assessment interventions on tolerance to chemotherapy in older people. Br J Cancer 112(9):1435–1444. https://www.nature.com/articles/bjc2015120

Puts MT, Hardt J, Monette J, Girre V, Springall E, Alibhai SM (2012) Use of geriatric assessment for older adults in the oncology setting: a systematic review. J Natl Cancer Inst 104(15):1133–1163. https://academic.oup.com/jnci/article/104/15/1134/949848

Wildiers H, Heeren P, Puts M, Topinkova E, Janssen-Heijnen ML, Extermann M, Falandry C, Artz A, Brain E, Colloca G et al (2014) International Society of Geriatric Oncology consensus on geriatric assessment in older patients with cancer. J Clin Oncol 32(24):2595–2603. https://doi.org/10.1200/JCO.2013.54.8347

Antonio M, Saldana J, Carmona-Bayonas A, Navarro V, Tebe C, Nadal M, Formiga F, Salazar R, Borras JM (2017) Geriatric assessment predicts survival and competing mortality in elderly patients with early colorectal cancer: Can it help in adjuvant therapy decision-making? Oncologist 22(8):934–943. https://www.nature.com/articles/bjc2017455

Vallet-Regi M, Manzano M, Rodriguez-Manas L, Checa Lopez M, Aapro M, Balducci L (2017) Management of cancer in the older age person: an approach to complex medical decisions. Oncologist 22(3):335–342. https://doi.org/10.1634/theoncologist.2016-0276

Lund CM, Vistisen KK, Olsen AP, Bardal P, Schultz M, Dolin TG, Ronholt F, Johansen JS, Nielsen DL (2021) The effect of geriatric intervention in frail older patients receiving chemotherapy for colorectal cancer: a randomised trial (GERICO). Br J Cancer 124(12):1949–1958. https://www.nature.com/articles/s41416-021-01367-0

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