Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channel

Kaupp, U. B. & Seifert, R. Cyclic nucleotide-gated ion channels. Physiol. Rev. 82, 769–824 (2002).

Article  CAS  PubMed  Google Scholar 

Craven, K. B. & Zagotta, W. N. CNG and HCN channels: two peas, one pod. Annu. Rev. Physiol. 68, 375–401 (2006).

Article  CAS  PubMed  Google Scholar 

Robinson, R. B. & Siegelbaum, S. A. Hyperpolarization-activated cation currents: from molecules to physiological function. Annu. Rev. Physiol. 65, 453–480 (2003).

Article  CAS  PubMed  Google Scholar 

Biel, M., Wahl-Schott, C., Michalakis, S. & Zong, X. Hyperpolarization-activated cation channels: from genes to function. Physiol. Rev. 89, 847–885 (2009).

Article  CAS  PubMed  Google Scholar 

James, Z. M. & Zagotta, W. N. Structural insights into the mechanisms of CNBD channel function. J. Gen. Physiol. 150, 225–244 (2017).

Article  PubMed  Google Scholar 

Yu, F. H., Yarov-Yarovoy, V., Gutman, G. A. & Catterall, W. A. Overview of molecular relationships in the voltage-gated ion channel superfamily. Pharmacol. Rev. 57, 387–395 (2005).

Article  CAS  PubMed  Google Scholar 

Rheinberger, J., Gao, X., Schmidpeter, P. A. M. & Nimigean, C. M. Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures. eLife 7, e39775 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Lee, C.-H. & MacKinnon, R. Structures of the human HCN1 hyperpolarization-activated channel. Cell 168, 111–120.e111 (2017).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Saponaro, A. et al. Gating movements and ion permeation in HCN4 pacemaker channels. Mol. Cell 81, 2929–2943.e2926 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li, M. et al. Structure of a eukaryotic cyclic-nucleotide-gated channel. Nature 542, 60–65 (2017).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schmidpeter, P. A. M., Gao, X., Uphadyay, V., Rheinberger, J. & Nimigean, C. M. Ligand binding and activation properties of the purified bacterial cyclic nucleotide–gated channel SthK. J. Gen. Physiol. 150, 821–834 (2018).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Marchesi, A. et al. An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel. Nat. Commun. 9, 3978 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Kesters, D. et al. Structure of the SthK carboxy-terminal region reveals a gating mechanism for cyclic nucleotide-modulated Ion channels. PLoS ONE 10, e0116369 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Florin, E. L., Moy, V. T. & Gaub, H. E. Adhesion forces between individual ligand-receptor pairs. Science 264, 415 (1994).

Article  CAS  PubMed  Google Scholar 

Thess, A. et al. Specific orientation and two-dimensional crystallization of the proteasome at metal-chelating lipid interfaces. J. Biol. Chem. 277, 36321–36328 (2002).

Article  CAS  PubMed  Google Scholar 

Nye, J. A. & Groves, J. T. Kinetic control of histidine-tagged protein surface density on supported lipid bilayers. Langmuir 24, 4145–4149 (2008).

Article  CAS  PubMed  Google Scholar 

Lolicato, M. et al. Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels. J. Biol. Chem. 286, 44811–44820 (2011).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zagotta, W. N. et al. Structural basis for modulation and agonist specificity of HCN pacemaker channels. Nature 425, 200–205 (2003).

Article  CAS  PubMed  Google Scholar 

Lolicato, M. et al. Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness. Nat. Chem. Biol. 10, 457–462 (2014).

Article  CAS  PubMed  Google Scholar 

Ebner, A. et al. A new, simple method for linking of antibodies to atomic force microscopy tips. Bioconjug. Chem. 18, 1176–1184 (2007).

Article  CAS  PubMed  Google Scholar 

Baumgartner, W. et al. Cadherin interaction probed by atomic force microscopy. Proc. Natl Acad. Sci. USA 97, 4005–4010 (2000).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Evans, E. & Ritchie, K. Dynamic strength of molecular adhesion bonds. Biophys. J. 72, 1541–1555 (1997).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang, J. et al. The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness. Nature 464, 932–936 (2010).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lo Giudice, C., Zhang, H., Wu, B. & Alsteens, D. Mechanochemical activation of class-B G-protein-coupled receptor upon peptide–ligand binding. Nano Lett. 20, 5575–5582 (2020).

Article  CAS  PubMed  Google Scholar 

Zhu, R. et al. Allosterically linked binding sites in serotonin transporter revealed by single molecule force spectroscopy. Front. Mol. Biosci. 7, 99 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Williams, P. M. Analytical descriptions of dynamic force spectroscopy: behaviour of multiple connections. Anal. Chim. Acta 479, 107–115 (2003).

Article  CAS  Google Scholar 

Rankl, C. et al. Multiple receptors involved in human rhinovirus attachment to live cells. Proc. Natl Acad. Sci. USA 105, 17778–17783 (2008).

Article  PubMed  PubMed Central  Google Scholar 

Sulchek, T. A. et al. Dynamic force spectroscopy of parallel individual Mucin1–antibody bonds. Proc. Natl Acad. Sci. USA 102, 16638–16643 (2005).

Article  CAS  PubMed  PubMed Central  Google Scholar 

White, D. S. et al. cAMP binding to closed pacemaker ion channels is non-cooperative. Nature 595, 606–610 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schmidpeter, P. A. M., Rheinberger, J. & Nimigean, C. M. Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel. Nat. Commun. 11, 6401 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dudko, O. K., Hummer, G. & Szabo, A. Intrinsic rates and activation free energies from single-molecule pulling experiments. Phys. Rev. Lett. 96, 108101 (2006).

Article  PubMed  Google Scholar 

Aman, T. K., Gordon, S. E. & Zagotta, W. N. Regulation of CNGA1 channel gating by interactions with the membrane. J. Biol. Chem. 291, 9939–9947 (2016).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brady, J. D. et al. Interplay between PIP3 and calmodulin regulation of olfactory cyclic nucleotide-gated channels. Proc. Natl Acad. Sci. USA 103, 15635–15640 (2006).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Asakawa, H., Yoshioka, S., Nishimura, K.-I. & Fukuma, T. Spatial distribution of lipid headgroups and water molecules at membrane/water interfaces visualized by three-dimensional scanning force microscopy. ACS Nano 6, 9013–9020 (2012).

Koehler, M. et al. Control of ligand-binding specificity using photocleavable linkers in AFM force spectroscopy. Nano Lett. 20, 4038–4042 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Miyagi, A. & Scheuring, S. Automated force controller for amplitude modulation atomic force microscopy. Rev. Sci. Instrum. 87, 053705 (2016).

Article  PubMed  Google Scholar 

Miyagi, A. & Scheuring, S. A novel phase-shift-based amplitude detector for a high-speed atomic force microscope. Rev. Sci. Instrum. 89, 083704 (2018).

Article  PubMed  Google Scholar 

Sali, A. & Blundell, T. L. Comparative protein modelling by satisfaction of spatial restraints. J. Mol. Biol. 234, 779–815 (1993).

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