STAT3 signaling promotes cardiac injury by upregulating NCOA4-mediated ferritinophagy and ferroptosis in high-fat-diet fed mice

Keywords

Ferroptosis

Ferritinophagy

Reactive oxygen species (ROS)

HFD-Induced cardiac injury

Obesity

STAT3

AbbreviationsPTGS2

prostaglandin-endoperoxide synthase 2

ROS

reactive oxygen species

NCOA4

nuclear receptor coactivator 4

STAT3

signal transducer and activator of transcription 3

ATG

autophagy related gene

OA/PA

oleic acid/palmitic acid

© 2023 The Authors. Published by Elsevier Inc.

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