Berkowitz L. Aggression: Its causes, consequences, and control. New York, Mcgraw-Hill. 1993;464–6.

Vitiello B, Stoff DM. Subtypes of aggression and their relevance to child psychiatry. J Am Acad Child Adolesc Psychiatry. 1997;36:307–15.

Article  CAS  PubMed  Google Scholar 

Bertsch K, Florange J, Herpertz SC. Understanding brain mechanisms of reactive aggression. Curr Psychiatry Rep. 2020;22:1–16.

Article  Google Scholar 

LeDoux J. The amygdala. Curr Biol. 2007;17:R868–74.

LaBar KS, LeDoux JE, Spencer DD, Phelps EA. Impaired fear conditioning following unilateral temporal lobectomy in humans. J Neurosci 1995;15:6846–55.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lotze M, Veit R, Anders S, Birbaumer N. Evidence for a different role of the ventral and dorsal medial prefrontal cortex for social reactive aggression: An interactive fMRI study. Neuroimage. 2007;34:470–8.

Article  CAS  PubMed  Google Scholar 

Buades-Rotger M, Engelke C, Beyer F, Keevil BG, Brabant G, Krämer UM. Endogenous testosterone is associated with lower amygdala reactivity to angry faces and reduced aggressive behavior in healthy young women. Sci Rep. 2016;6:38538.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kramer UM, Jansma H, Tempelmann C, Munte TF. Tit-for-tat: The neural basis of reactive aggression. Neuroimage. 2007;38:203–11.

Article  PubMed  Google Scholar 

Nikolic M, Pezzoli P, Jaworska N, Seto MC. Brain responses in aggression-prone individuals: A systematic review and meta-analysis of functional magnetic resonance imaging (fMRI) studies of anger- and aggression-eliciting tasks. Prog Neuropsychopharmacol Biol Psychiatry. 2022;110596:110596.

Article  Google Scholar 

Wen Z, Raio CM, Pace-Schott EF, Lazar SW, LeDoux JE, Phelps EA, et al. Temporally and anatomically specific contributions of the human amygdala to threat and safety learning. Proc Natl Acad Sci USA. 2022;119:2204066119.

Article  Google Scholar 

Coccaro EF, McCloskey MS, Fitzgerald DA, Phan KL. Amygdala and orbitofrontal reactivity to social threat in individuals with impulsive aggression. Biol Psychiatry. 2007;62:168–78.

Article  PubMed  Google Scholar 

McCloskey MS, Phan KL, Angstadt M, Fettich KC, Keedy S, Coccaro EF. Amygdala hyperactivation to angry faces in intermittent explosive disorder. J Psychiatr Res. 2016;79:34–41.

Article  PubMed  Google Scholar 

Ogbuagu N, Keedy S, Phan KL, Coccaro EF. Neural responses to induced emotion and response to social threat in intermittent explosive disorder. Psychiatry Res Neuroimaging. 2021;318:111388.

Article  PubMed  Google Scholar 

Seok JW, Cheong C. Gray matter deficits and dysfunction in the insula among individuals with intermittent explosive disorder. Front Psychiatry. 2020;11:439.

Article  PubMed  PubMed Central  Google Scholar 

da Cunha-Bang S, Fisher PM, Hjordt LV, Perfalk E, Persson Skibsted A, Bock C, et al. Violent offenders respond to provocations with high amygdala and striatal reactivity. Soc Cogn Affect Neurosci. 2017;12:802–10.

Article  PubMed  PubMed Central  Google Scholar 

Lee TMC, Chan SC, Raine A. Hyperresponsivity to threat stimuli in domestic violence offenders: A functional magnetic resonance imaging study. J Clin Psychiatry. 2009;70:36–45.

Article  PubMed  Google Scholar 

Schienle A, Wabnegger A, Leitner M, Leutgeb V. Neuronal correlates of personal space intrusion in violent offenders. Brain Imaging Behav. 2017;11:454–60.

Article  PubMed  Google Scholar 

Ewbank MP, Passamonti L, Hagan CC, Goodyer IM, Calder AJ, Fairchild G. Psychopathic traits influence amygdala-anterior cingulate cortex connectivity during facial emotion processing. Soc Cogn Affect Neurosci. 2018;13:525–34.

Article  PubMed  PubMed Central  Google Scholar 

Kendrick KM, Guastella AJ & Becker B. Overview of human oxytocin research. in Current Topics in Behavioral Neurosciences 35 321–48 (Springer Verlag, 2018).

Shamay-Tsoory SG, Abu-Akel A. The social salience hypothesis of oxytocin. Biol Psychiatry. 2016;79:194–202.

Article  CAS  PubMed  Google Scholar 

Olivera-Pasilio V, Dabrowska J. Oxytocin promotes accurate fear discrimination and adaptive defensive behaviors. Front Neurosci. 2020;14:583878.

Article  PubMed  PubMed Central  Google Scholar 

Ne’eman R, Perach-Barzilay N, Fischer-Shofty M, Atias A, Shamay-Tsoory SG. Intranasal administration of oxytocin increases human aggressive behavior. Horm Behav. 2016;80:125–31.

Article  PubMed  Google Scholar 

Domes G, Heinrichs M, Gläscher J, Büchel C, Braus DF, Herpertz SC. Oxytocin attenuates amygdala responses to emotional faces regardless of valence. Biol Psychiatry. 2007;62:1187–90.

Article  CAS  PubMed  Google Scholar 

Kirsch P, Esslinger C, Chen Q, Mier D, Lis S, Siddhanti S, et al. Oxytocin modulates neural circuitry for social cognition and fear in humans. J Neurosci. 2005;25:11489–93.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kanat M, Heinrichs M, Schwarzwald R, Domes G. Oxytocin attenuates neural reactivity to masked threat cues from the eyes. Neuropsychopharmacology. 2015;40:287–95.

Article  CAS  PubMed  Google Scholar 

Radke S, Volman I, Kokal I, Roelofs K, de Bruijn E, Toni I. Oxytocin reduces amygdala responses during threat approach. Psychoneuroendocrinology. 2017;79:160–6.

Article  CAS  PubMed  Google Scholar 

Liu C, Lan C, Li K, Zhou F, Yao S, Xu L, et al. Oxytocinergic Modulation of Threat-Specific Amygdala Sensitization in Humans Is Critically Mediated by Serotonergic Mechanisms. Biol psychiatry Cogn Neurosci Neuroimag. 2021;6:1081–9.

Google Scholar 

Gedeon T, Parry J, Völlm B. The role of oxytocin in antisocial personality disorders: A systematic review of the literature. Front Psychiatry. 2019;10:76.

Article  PubMed  PubMed Central  Google Scholar 

Bertsch K, Gamer M, Schmidt B, Schmidinger I, Walther S, Kästel T, et al. Oxytocin and reduction of social threat hypersensitivity in women with borderline personality disorder. Am J Psychiatry. 2013;170:1169–77.

Article  PubMed  Google Scholar 

Antisocial behaviour and conduct disorders in children and young people: recognition and management. London: National Institute for Health and Care Excellence (NICE). 2017. PMID: 32073810. https://pubmed.ncbi.nlm.nih.gov/32073810/.

Brazil IA, van Dongen JDM, Maes JHR, Mars RB, Baskin-Sommers AR. Classification and treatment of antisocial individuals: From behavior to biocognition. Neurosci Biobehav Rev. 2018;91:259–77.

Article  CAS  PubMed  Google Scholar 

Alcorn JL, Rathnayaka N, Swann AC, Moeller FG, Lane SD. Effects of Intranasal oxytocin on aggressive responding in antisocial personality disorder. Psychol Rec 2015;65:691–703.

Article  PubMed  PubMed Central  Google Scholar 

Timmermann M, Jeung H, Schmitt R, Boll S, Freitag CM, Bertsch K, et al. Oxytocin improves facial emotion recognition in young adults with antisocial personality disorder. Psychoneuroendocrinology. 2017;85:158–64.

Article  CAS  PubMed  Google Scholar 

Gao S, Becker B, Luo L, Geng Y, Zhao W, Yin Y, et al. Oxytocin, the peptide that bonds the sexes also divides them. Proc Natl Acad Sci USA. 2016;113:7650–4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rilling JK, DeMarco AC, Hackett PD, Chen X, Gautam P, Stair S, et al. Sex differences in the neural and behavioral response to intranasal oxytocin and vasopressin during human social interaction. Psychoneuroendocrinology. 2014;39:237–48.

Article  CAS  PubMed  Google Scholar 

Lieberz J, Scheele D, Spengler FB, Matheisen T, Schneider L, Stoffel-Wagner B, et al. Kinetics of oxytocin effects on amygdala and striatal reactivity vary between women and men. Neuropsychopharmacology. 2020;45:1134–40.

Article  CAS  PubMed  Google Scholar 

Gamer M, Büchel C. Amygdala activation predicts gaze toward fearful eyes. J Neurosci. 2009;29:9123–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gamer M, Zurowski B, Büchel C. Different amygdala subregions mediate valence-related and attentional effects of oxytocin in humans. Proc Natl Acad Sci USA. 2010;107:9400–5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hubble K, Daughters K, Manstead AS, Rees A, Thapar A, van Goozen SH. Oxytocin Reduces Face Processing Time but Leaves Recognition Accuracy and Eye-Gaze Unaffected. J Int Neuropsychol Soc. 2017;23:23–33.

Article  PubMed  Google Scholar 

Wechsler D. Wechsler Abbreviated Scale of Intelligence. New York, NY Psychol. Corp. Harcourt Brace Co. 1999.

Paulhus, DL; Neumann, CS; Hare, RD Manual for the Self-Report Psychopathy (SRP) scale: 4th edition. Toronto Multi-Health Syst. (2016).

Laux, L, Glanzmann, P, Schaffner, P & Spielberger, CD Das State-Trait-Angstinventar (STAI). Weinheim: Beltz Testgesellschaft (1981).

Goldstein RB, Compton WM, Pulay AJ, Ruan WJ, Pickering RP, Stinson FS, et al. Antisocial behavioral syndromes and DSM-IV drug use disorders in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Drug Alcohol Depend. 2007;90:145–58.

Article  PubMed  PubMed Central  Google Scholar 

Seitz KI, Leitenstorfer J, Krauch M, Hillmann K, B