Introduction Endometriosis impacts 1 in 10 women and can be a debilitating disease. Late diagnosis is a major challenge with Endometriosis, contributing further to the exacerbation of symptoms and suboptimal clinical management. Regardless of the commonality of the condition, public awareness and research around endometriosis is severely lacking. Methods To explore the knowledge base about Endometriosis we developed a digital cross-sectional study. We used the Qualtrics XM platform and developed a questionnaire. The primary objective of the study was to report the understanding of Endometriosis among healthcare professionals in a mental healthcare setting in the UK. Results: We gathered the responses of 144 healthcare professionals, although only 68 participants responded to all questions. Approximately 96% of participants agreed that there is a need for a comprehensive clinical strategy where mental health care services could assist women very early in the pathway. Around 63.1% confirmed awareness of endometriosis although the χ^2 (p-value=0.158) test showed that the perceived clinical knowledge was not necessarily associated with their profession. Over 92% of participants confirmed that it would be useful to conduct mental health-based research among endometriosis patients. Discussion: It is clear than patients with endometriosis would greatly benefit from a streamlined clinical pathway. It would also have financial benefits to the NHS, including less visits to A&E. The absence of comprehensive knowledge and understanding amongst healthcare professional on endometriosis leads to delayed diagnosis and treatment, exacerbating their psychological and physiological symptoms. Conclusions: Our study shows the importance of funding mental health research to further add to the body of knowledge in order to develop evidence based clinical practices that are equally acceptable to women with endometriosis. This will have benefits for both the patients, healthcare professional, and also the NHS. It will enable for better treatment pathways and symptom management, aiding the development for improved healthcare policies.

The authors have declared no competing interest.

This study did not receive any funding

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Yes

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

Ethics committee of the Health Research Authority UK gave ethical approval for this work

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

Yes

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

Yes

I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.

Yes

All data produced in the present work are contained in the manuscript