Lee SH, Jeong SK, Ahn SK. An update of the defensive barrier function of skin. Yonsei Med J. 2006;47(3):293–306.
Article CAS PubMed PubMed Central Google Scholar
Williams HC. Clinical practice. Atopic dermatitis N Engl J Med. 2005;352(22):2314–24.
Article CAS PubMed Google Scholar
Roberts V, Main B, Timpson NJ, Haworth S. Genome-wide association study identifies genetic associations with perceived age. J Invest Dermatol. 2020;140(12):2380–5.
Article CAS PubMed PubMed Central Google Scholar
Schmauck-Medina T, Moliere A, Lautrup S, Zhang J, Chlopicki S, Madsen HB, et al. New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary. Aging. 2022;14(16):6829–39.
Article PubMed PubMed Central Google Scholar
Lopez-Otin C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 2013;153(6):1194–217.
Article CAS PubMed PubMed Central Google Scholar
Muzumdar S, Ferenczi K. Nutrition and youthful skin. Clin Dermatol. 2021;39(5):796–808.
Rhodes LE, Durham BH, Fraser WD, Friedmann PS. Dietary fish oil reduces basal and ultraviolet B-generated PGE2 levels in skin and increases the threshold to provocation of polymorphic light eruption. J Invest Dermatol. 1995;105(4):532–5.
Article CAS PubMed Google Scholar
Kim HH, Cho S, Lee S, Kim KH, Cho KH, Eun HC, et al. Photoprotective and anti-skin-aging effects of eicosapentaenoic acid in human skin in vivo. J Lipid Res. 2006;47(5):921–30.
Article CAS PubMed Google Scholar
Wang P, Yan G, Xue H, Shen S, Cao Y, Zhang G, et al. Proteomics and lipidomics reveal the protective mechanism of dietary n-3 PUFA supplementation for photoaging. Food Funct. 2021;12(17):7883–96.
Article CAS PubMed Google Scholar
Gruber F, Ornelas CM, Karner S, Narzt MS, Nagelreiter IM, Gschwandtner M, et al. Nrf2 deficiency causes lipid oxidation, inflammation, and matrix-protease expression in DHA-supplemented and UVA-irradiated skin fibroblasts. Free Radic Biol Med. 2015;88(Pt B):439–51.
Article CAS PubMed Google Scholar
Helal NA, Eassa HA, Amer AM, Eltokhy MA, Edafiogho I, Nounou MI. Nutraceuticals’ novel formulations: the good, the bad, the unknown and patents involved. Recent Pat Drug Deliv Formul. 2019;13(2):105–56.
Article CAS PubMed PubMed Central Google Scholar
Latreille J, Kesse-Guyot E, Malvy D, Andreeva V, Galan P, Tschachler E, et al. Association between dietary intake of n-3 polyunsaturated fatty acids and severity of skin photoaging in a middle-aged Caucasian population. J Dermatol Sci. 2013;72(3):233–9.
Article CAS PubMed Google Scholar
Curtis R, Geesaman BJ, DiStefano PS. Ageing and metabolism: drug discovery opportunities. Nat Rev Drug Discov. 2005;4(7):569–80.
Article CAS PubMed Google Scholar
Davey Smith G, Hemani G. Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Hum Mol Genet. 2014;23(R1):R89-98.
Article CAS PubMed PubMed Central Google Scholar
Sanderson E, Smith GD, Windmeijer F, Bowden J. Corrigendum to: an examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings. Int J Epidemiol. 2020;49(3):1057.
Article PubMed PubMed Central Google Scholar
Shin SY, Fauman EB, Petersen AK, Krumsiek J, Santos R, Huang J, et al. An atlas of genetic influences on human blood metabolites. Nat Genet. 2014;46(6):543–50.
Article CAS PubMed PubMed Central Google Scholar
Roederer M, Quaye L, Mangino M, Beddall MH, Mahnke Y, Chattopadhyay P, et al. The genetic architecture of the human immune system: a bioresource for autoimmunity and disease pathogenesis. Cell. 2015;161(2):387–403.
Article CAS PubMed PubMed Central Google Scholar
Kettunen J, Demirkan A, Wurtz P, Draisma HH, Haller T, Rawal R, et al. Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA. Nat Commun. 2016;7:11122.
Article CAS PubMed PubMed Central Google Scholar
Zuber V, Colijn JM, Klaver C, Burgess S. Selecting likely causal risk factors from high-throughput experiments using multivariable Mendelian randomization. Nat Commun. 2020;11(1):29.
Article CAS PubMed PubMed Central Google Scholar
Mi J, Jiang L, Liu Z, Wu X, Zhao N, Wang Y, et al. Identification of blood metabolites linked to the risk of cholelithiasis: a comprehensive Mendelian randomization study. Hepatol Int. 2022. https://doi.org/10.1007/s12072-022-10360-5.
Ahola-Olli AV, Mustelin L, Kalimeri M, Kettunen J, Jokelainen J, Auvinen J, et al. Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts. Diabetologia. 2019;62(12):2298–309.
Article CAS PubMed PubMed Central Google Scholar
Soininen P, Kangas AJ, Wurtz P, Suna T, Ala-Korpela M. Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics. Circ Cardiovasc Genet. 2015;8(1):192–206.
Article CAS PubMed Google Scholar
Zhou J, Mi J, Peng Y, Han H, Liu Z. Causal associations of obesity with the intervertebral degeneration, low back pain, and sciatica: a two-sample Mendelian randomization study. Front Endocrinol. 2021;12:740200.
Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557–60.
Article PubMed PubMed Central Google Scholar
Bowden J, Del Greco MF, Minelli C, Davey Smith G, Sheehan NA, Thompson JR. Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic. Int J Epidemiol. 2016;45(6):1961–74.
PubMed PubMed Central Google Scholar
Burgess S, Thompson SG. Interpreting findings from Mendelian randomization using the MR-Egger method. Eur J Epidemiol. 2017;32(5):377–89.
Article PubMed PubMed Central Google Scholar
Bowden J, Davey Smith G, Haycock PC, Burgess S. Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator. Genet Epidemiol. 2016;40(4):304–14.
Article PubMed PubMed Central Google Scholar
Verbanck M, Chen CY, Neale B, Do R. Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases. Nat Genet. 2018;50(5):693–8.
Article CAS PubMed PubMed Central Google Scholar
Sanderson E, Spiller W, Bowden J. Testing and correcting for weak and pleiotropic instruments in two-sample multivariable Mendelian randomization. Stat Med. 2021;40(25):5434–52.
Article PubMed PubMed Central Google Scholar
Foley CN, Staley JR, Breen PG, Sun BB, Kirk PDW, Burgess S, et al. A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits. Nat Commun. 2021;12(1):764.
Article CAS PubMed PubMed Central Google Scholar
Lord J, Jermy B, Green R, Wong A, Xu J, Legido-Quigley C, et al. Mendelian randomization identifies blood metabolites previously linked to midlife cognition as causal candidates in Alzheimer’s disease. Proc Natl Acad Sci USA. 2021. https://doi.org/10.1073/pnas.2009808118.
Article PubMed PubMed Central Google Scholar
Hemani G, Zheng J, Elsworth B, Wade KH, Haberland V, Baird D, et al. The MR-Base platform supports systematic causal inference across the human phenome. Elife. 2018. https://doi.org/10.7554/eLife.34408.
Article PubMed PubMed Central Google Scholar
Yavorska OO, Burgess S. MendelianRandomization: an R package for performing Mendelian randomization analyses using summarized data. Int J Epidemiol. 2017;46(6):1734–9.
Article PubMed PubMed Central Google Scholar
Gilchrest BA. Skin aging and photoaging: an overview. J Am Acad Dermatol. 1989;21(3 Pt 2):610–3.
Article CAS PubMed Google Scholar
Gomez EC, Berman B. The aging skin. Clin Geriatr Med. 1985;1(1):285–305.
留言 (0)