Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49.

Article  PubMed  Google Scholar 

Hundal R, Shaffer EA. Gallbladder cancer: epidemiology and outcome. Clin Epidemiol. 2014;6(99):99–109.

PubMed  PubMed Central  Google Scholar 

Huang J, Patel HK, Boakye D, Chandrasekar VT, Koulaouzidis A, Lucero-Prisno DE III, et al. Worldwide distribution, associated factors, and trends of gallbladder cancer: a global country-level analysis. Cancer Lett. 2021;521:238–51.

Article  CAS  PubMed  Google Scholar 

Lazcano-Ponce EC, Miquel JF, Munoz N, Herrero R, Ferrecio C, Wistuba II, et al. Epidemiology and molecular pathology of gallbladder cancer. CA Cancer J Clin. 2001;51(6):349–64.

Article  CAS  PubMed  Google Scholar 

Ouyang G, Liu Q, Wu Y, Liu Z, Lu W, Li S, et al. The global, regional, and national burden of gallbladder and biliary tract cancer and its attributable risk factors in 195 countries and territories, 1990 to 2017: a systematic analysis for the Global Burden of Disease Study 2017. Cancer. 2021;127(13):2238–50.

Article  PubMed  Google Scholar 

Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2022. CA Cancer J Clin. 2022;72(1):7–33.

Article  PubMed  Google Scholar 

Bruni L, Albero G, Serrano B, Mena M, Gómez D, Muñoz J, et al. ICO/IARC information centre on HPV and cancer (HPV information centre). Human papillomavirus and related diseases in the world. Summ Rep. 2019;30(17).

Khan ZA, Khan MU, Brand M. Gallbladder cancer in Africa: a higher than expected rate in a “low-risk” population. Surgery. 2022;171(4):855–8.

Article  PubMed  Google Scholar 

Hsing AW, Gao YT, Han TQ, Rashid A, Sakoda LC, Wang BS, et al. Gallstones and the risk of biliary tract cancer: a population-based study in China. Br J Cancer. 2007;97(11):1577–82.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rawla P, Sunkara T, Thandra KC, Barsouk A. Epidemiology of gallbladder cancer. Clin Exp Hepatol. 2019;5(2):93–102.

Article  PubMed  PubMed Central  Google Scholar 

Andrén-Sandberg Å. Diagnosis and management of gallbladder cancer. North Am J Med Sci. 2012;4(7):293–9.

Article  Google Scholar 

Henson DE, Albores-Saavedra J, Code D. Carcinoma of the gallbladder. Histologic types, stage of disease, grade, and survival rates. Cancer. 1992;70(6):1493–7.

Article  CAS  PubMed  Google Scholar 

Hsing AW, Bai Y, Andreotti G, Rashid A, Deng J, Chen J, et al. Family history of gallstones and the risk of biliary tract cancer and gallstones: a population-based study in Shanghai, China. Int J Cancer. 2007;121(4):832–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schmidt MA, Marcano-Bonilla L, Roberts LR. Gallbladder cancer: epidemiology and genetic risk associations. Chin Clin Oncol. 2019;8(4):31.

Article  PubMed  Google Scholar 

Li M, Liu F, Zhang F, Zhou W, Jiang X, Yang Y, et al. Genomic ERBB2 / ERBB3 mutations promote PD-L1-mediated immune escape in gallbladder cancer: a whole-exome sequencing analysis. Gut. 2018. https://doi.org/10.1136/gutjnl-2018-316039.

Article  PubMed  Google Scholar 

Geyer PE, Kulak NA, Pichler G, Holdt LM, Teupser D, Mann M. Plasma proteome profiling to assess human health and disease. Cell Syst. 2016;2(3):185–95.

Article  CAS  PubMed  Google Scholar 

Priya R, Jain V, Akhtar J, Chauhan G, Sakhuja P, Goyal S, et al. Plasma-derived candidate biomarkers for detection of gallbladder carcinoma. Sci Rep. 2021;11(1):23554.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tan Y, Ma S, Wang F, Meng H, Mei C, Liu A, et al. Proteomic-based analysis for identification of potential serum biomarkers in gallbladder cancer. Oncol Rep. 2011;26(4):853–9.

CAS  PubMed  Google Scholar 

Hanash SM, Pitteri SJ, Faca VM. Mining the plasma proteome for cancer biomarkers. Nature. 2008;452(7187):571–9.

Article  CAS  PubMed  Google Scholar 

Szajnik M, Derbis M, Lach M, Patalas P, Michalak M, Drzewiecka H, et al. Exosomes in plasma of patients with ovarian carcinoma: potential biomarkers of tumor progression and response to therapy. Gynecol Obstet. 2013;s4:003.

Google Scholar 

Baichan P, Naicker P, Devar JWS, Smith M, Candy GP, Nweke E. Targeting gallbladder cancer: a pathway based perspective. Mol Biol Rep. 2020;47(3):2361–9.

Article  CAS  PubMed  Google Scholar 

Buchegger K, Silva R, López J, Ili C, Araya JC, Leal P, et al. The ERK/MAPK pathway is overexpressed and activated in gallbladder cancer. Pathol - Res Pract. 2017;213(5):476–82.

Article  CAS  PubMed  Google Scholar 

King D, Yeomanson D, Bryant HE. PI3King the lock: targeting the PI3K/Akt/mTOR pathway as a novel therapeutic strategy in neuroblastoma. J Pediatr Hematol Oncol. 2015;37(4):245–51.

Article  CAS  PubMed  Google Scholar 

Liu L, Yang Z, Wang C, Miao X, Liu Z, Li D, et al. The expression of Notch 1 and Notch 3 in gallbladder cancer and their clinicopathological significance. Pathol Oncol Res. 2016;22(3):483–92.

Article  CAS  PubMed  Google Scholar 

Gillet LC, Navarro P, Tate S, Röst H, Selevsek N, Reiter L, et al. Targeted data extraction of the MS/MS spectra generated by data-independent acquisition: a new concept for consistent and accurate proteome analysis. Mol Cell Proteomics. 2012. https://doi.org/10.1074/mcp.O111.016717.

Article  PubMed  PubMed Central  Google Scholar 

Ludwig C, Gillet L, Rosenberger G, Amon S, Collins BC, Aebersold R. Data-independent acquisition-based SWATH-MS for quantitative proteomics: a tutorial. Mol Syst Biol. 2018;14(8): e8126.

Article  PubMed  PubMed Central  Google Scholar 

Nweke EE, Naicker P, Aron S, Stoychev S, Devar J, Tabb DL, et al. SWATH-MS based proteomic profiling of pancreatic ductal adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathways. PLoS ONE. 2020;15(10): e0240453.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Amin M, Edge S, Greene F, Byrd D, Brookland R, Washington M, et al. AJCC cancer staging manual. 8th ed. New York: Springer; 2017.

Book  Google Scholar 

Batth TS, Tollenaere MAX, Rüther P, Gonzalez-Franquesa A, Prabhakar BS, Bekker-Jensen S, et al. Protein aggregation capture on microparticles enables multipurpose proteomics sample preparation*. Mol Cell Proteomics. 2019;18(5):1027–35.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fabregat A, Sidiropoulos K, Viteri G, Forner O, Marin-Garcia P, Arnau V, et al. Reactome pathway analysis: a high-performance in-memory approach. BMC Bioinform. 2017;18(1):1–9.

Article  Google Scholar 

Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003;13(11):2498–504.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Doncheva NT, Morris JH, Gorodkin J, Jensen LJ. Cytoscape StringApp: network analysis and visualization of proteomics data. J Proteome Res. 2019;18(2):623–32.

Article  CAS  PubMed  Google Scholar 

Mi H, Ebert D, Muruganujan A, Mills C, Albou LP, Mushayamaha T, et al. PANTHER version 16: a revised family classification, tree-based classification tool, enhancer regions and extensive API. Nucleic Acids Res. 2021;49(D1):D394-403.

Article  CAS  PubMed  Google Scholar 

Sachan A, Saluja SS, Nekarakanti PK, Nimisha, Mahajan B, Nag HH, et al. Raised CA19–9 and CEA have prognostic relevance in gallbladder carcinoma. BMC Cancer. 2020;20(1):826.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang YF, Feng FL, Zhao XH, Ye ZX, Zeng HP, Li Z, et al. Combined detection tumor markers for diagnosis and prognosis of gallbladder cancer. World J Gastroenterol. 2014;20(14):4085–92.

Article  PubMed  PubMed Central  Google Scholar 

Saluja SS, Gulati M, Garg PK, Pal H, Pal S, Sahni P, et al. Endoscopic or percutaneous biliary drainage for gallbladder cancer: a randomized trial and quality of life assessment. Clin Gastroenterol Hepatol. 2008;6(8):944–50.

Article  PubMed  Google Scholar 

Stevenson DK, Vreman HJ, Wong RJ. Bilirubin production and the risk of bilirubin neurotoxicity. Semin Perinatol. 2011;35(3):121–6.

Article  PubMed  Google Scholar 

Erlinger TP, Muntner P, Helzlsouer KJ. WBC count and the risk of cancer mortality in a national sample of U.S. adults: results from the second national health and nutrition examination survey mortality study. Cancer Epidemiol Biomark Prev. 2004;13(6):1052–6.

Article  Google Scholar 

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