Kvarnström, M., Ottosson, V., Nordmark, B. & Wahren-Herlenius, M. Incident cases of primary Sjögren’s syndrome during a 5-year period in Stockholm County: a descriptive study of the patients and their characteristics. Scand. J. Rheumatol. 44, 135–142 (2015).
Mariette, X. & Criswell, L. A. Primary Sjögren’s syndrome. N. Engl. J. Med. 378, 931–939 (2018).
Brito-Zerón, P. et al. Epidemiological profile and north-south gradient driving baseline systemic involvement of primary Sjögren’s syndrome. Rheumatology 59, 2350–2359 (2020).
Shiboski, C. H. et al. 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren’s syndrome: a consensus and data-driven methodology involving three international patient cohorts. Ann. Rheum. Dis. 76, 9–16 (2017).
Mofors, J. et al. Infections increase the risk of developing Sjögren’s syndrome. J. Intern. Med. 285, 670–680 (2019).
Article CAS PubMed Google Scholar
Mofors, J. et al. Concomitant Ro/SSA and La/SSB antibodies are biomarkers for the risk of venous thromboembolism and cerebral infarction in primary Sjögren’s syndrome. J. Intern. Med. 286, 458–468 (2019).
Article CAS PubMed PubMed Central Google Scholar
Bartoloni, E. et al. Cardiovascular disease risk burden in primary Sjögren’s syndrome: results of a population-based multicentre cohort study. J. Intern. Med. 278, 185–192 (2015).
Article CAS PubMed Google Scholar
Nocturne, G. & Mariette, X. Sjögren syndrome-associated lymphomas: an update on pathogenesis and management. Br. J. Haematol. 168, 317–327 (2015).
Article CAS PubMed Google Scholar
Theander, E. et al. Lymphoma and other malignancies in primary Sjögren’s syndrome: a cohort study on cancer incidence and lymphoma predictors. Ann. Rheum. Dis. 65, 796–803 (2006).
Article CAS PubMed Google Scholar
Ambrosi, A., Sonesson, S. E. & Wahren-Herlenius, M. Molecular mechanisms of congenital heart block. Exp. Cell Res. 325, 2–9 (2014).
Article CAS PubMed Google Scholar
Ramos-Casals, M. et al. EULAR recommendations for the management of Sjögren’s syndrome with topical and systemic therapies. Ann. Rheum. Dis. 79, 3–18 (2020).
Article CAS PubMed Google Scholar
Seror, R., Nocturne, G. & Mariette, X. Current and future therapies for primary Sjögren syndrome. Nat. Rev. Rheumatol. 17, 475–486 (2021).
Bodewes, I. L. A., Björk, A., Versnel, M. A. & Wahren-Herlenius, M. Innate immunity and interferons in the pathogenesis of Sjögren’s syndrome. Rheumatology https://doi.org/10.1093/rheumatology/key360 (2019).
Article PubMed PubMed Central Google Scholar
Nocturne, G. & Mariette, X. B cells in the pathogenesis of primary Sjögren syndrome. Nat. Rev. Rheumatol. 14, 133–145 (2018).
Article CAS PubMed Google Scholar
Salomonsson, S. et al. Cellular basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjögren’s syndrome. Arthritis Rheum. 48, 3187–3201 (2003).
Article CAS PubMed Google Scholar
Bombardieri, M., Lewis, M. & Pitzalis, C. Ectopic lymphoid neogenesis in rheumatic autoimmune diseases. Nat. Rev. Rheumatol. 13, 141–154 (2017).
Article CAS PubMed Google Scholar
Ulff-Møller, C. J., Svendsen, A. J., Viemose, L. N. & Jacobsen, S. Concordance of autoimmune disease in a nationwide Danish systemic lupus erythematosus twin cohort. Semin. Arthritis Rheum. 47, 538–544 (2018).
Silman, A. J. et al. Twin concordance rates for rheumatoid arthritis: results from a nationwide study. Br. J. Rheumatol. 32, 903–907 (1993).
Article CAS PubMed Google Scholar
Björk, A., Mofors, J. & Wahren-Herlenius, M. Environmental factors in the pathogenesis of primary Sjögren’s syndrome. J. Intern. Med. 287, 475–492 (2020).
Kuo, C. F. et al. Familial risk of Sjögren’s syndrome and co-aggregation of autoimmune diseases in affected families: a nationwide population study. Arthritis Rheumatol. 67, 1904–1912 (2015).
Article PubMed PubMed Central Google Scholar
Lee, W. S. & Yoo, W. H. Primary Sjögren’s syndrome in monozygotic twins. Int. J. Rheum. Dis. 17, 578–579 (2014).
Bolstad, A. I., Haga, H. J., Wassmuth, R. & Jonsson, R. Monozygotic twins with primary Sjögren’s syndrome. J. Rheumatol. 27, 2264–2266 (2000).
Houghton, K. M., Cabral, D. A., Petty, R. E. & Tucker, L. B. Primary Sjögren’s syndrome in dizygotic adolescent twins: one case with lymphocytic interstitial pneumonia. J. Rheumatol. 32, 1603–1606 (2005).
Scofield, R. H., Kurien, B. T. & Reichlin, M. Immunologically restricted and inhibitory anti-Ro/SSA in monozygotic twins. Lupus 6, 395–398 (1997).
Article CAS PubMed Google Scholar
Imgenberg-Kreuz, J., Rasmussen, A., Sivils, K. & Nordmark, G. Genetics and epigenetics in primary Sjögren’s syndrome. Rheumatology 60, 2085–2098 (2021).
Article CAS PubMed PubMed Central Google Scholar
Ice, J. A. et al. Genetics of Sjögren’s syndrome in the genome-wide association era. J. Autoimmun. 39, 57–63 (2012).
Article CAS PubMed PubMed Central Google Scholar
Li, Y. et al. A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren’s syndrome at 7q11.23. Nat. Genet. 45, 1361–1365 (2013).
Article CAS PubMed Google Scholar
Song, I. W. et al. Identification of susceptibility gene associated with female primary Sjögren’s syndrome in Han Chinese by genome-wide association study. Hum. Genet. 135, 1287–1294 (2016).
Article CAS PubMed Google Scholar
Taylor, K. E. et al. Genome-wide association analysis reveals genetic heterogeneity of Sjögren’s syndrome according to ancestry. Arthritis Rheumatol. 69, 1294–1305 (2017).
Article CAS PubMed PubMed Central Google Scholar
Khatri, B. et al. Genome-wide association study identifies Sjögren’s risk loci with functional implications in immune and glandular cells. Nat. Commun. 13, 4287 (2022).
Article CAS PubMed PubMed Central Google Scholar
Lessard, C. J. et al. Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren’s syndrome. Nat. Genet. 45, 1284–1292 (2013).
Article CAS PubMed Google Scholar
Thorlacius, G. E. et al. Genetic and clinical basis for two distinct subtypes of primary Sjögren’s syndrome. Rheumatology 60, 837–848 (2021).
Carapito, R. et al. A new MHC-linked susceptibility locus for primary Sjögren’s syndrome: MICA. Hum. Mol. Genet. 26, 2565–2576 (2017).
Article CAS PubMed PubMed Central Google Scholar
Zhao, J. et al. A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases. Nat. Genet. 49, 433–437 (2017).
Article CAS PubMed PubMed Central Google Scholar
Li, H. et al. Identification of a Sjögren’s syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons. PLoS Genet. 13, e1006820 (2017).
Article PubMed PubMed Central Google Scholar
Qu, S. et al. Common variants near IKZF1 are associated with primary Sjögren’s syndrome in Han Chinese. PLoS ONE 12, e0177320 (2017).
Article PubMed PubMed Central Google Scholar
Bolstad, A. I. et al. Association between genetic variants in the tumour necrosis factor/lymphotoxin α/lymphotoxin β locus and primary Sjogren’s syndrome in Scandinavian samples. Ann. Rheum. Dis. 71, 981–988 (2012).
Article CAS PubMed Google Scholar
Musone, S. L. et al. Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases. Genes Immun. 12, 176–182 (2011).
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