*Pathology Department, Allegheny General Hospital, Pittsburgh, PA;

†Pathology Department, Medical College of Wisconsin, Milwaukee, WI;

‡Division of Dermatology, Loyola University Medical Center, Maywood, IL;

§Department of Pathology and Laboratory Medicine, Loyola University Medical Center, Maywood, IL;

¶Stritch School of Medicine, Loyola University Chicago, Maywood, IL; and

‖Division of Infectious Diseases, Department of Medicine, Loyola University Medical Center, Maywood, IL.

Correspondence: Feifan Chen, MD, Department of Pathology, Allegheny General Hospital, 320 E North Ave, Pittsburgh, PA, 15212 (e-mail: [email protected]).

The authors declare that they have no affiliations with or involvement in any organization or entity with any financial interest in the subject matter or materials discussed in this manuscript.

Disclaimer: There are currently no FDA-approved therapy for protothecaosis.

Ethical Compliance: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.