Arterial stiffness is considered an important marker for cardiovascular mortality and morbidity [1]. Increased arterial stiffness has been reported to be associated with increased cardiovascular disease and disease severity [[2], [3]]. Studies have reported that increased arterial stiffness is associated with various cardiac arrhythmias, including atrial fibrillation (AF), first-degree atrioventricular block, and complete atrioventricular block [[4], [5], [6]]. One of the parameters used to assess arterial stiffness is the cardio-ankle brachial index (CAVI) [2]. Studies have shown that CAVI assessment is a useful method to evaluate both arterial stiffness and the risk of subclinical coronary atherosclerosis in asymptomatic patients [7,8]. Compared to other methods of assessing arterial stiffness, CAVI has the advantages of being easy to measure, easily reproducible, operator independent, and less affected by blood pressure [9].

Arterial hypertension has been shown to be associated with cardiac arrhythmias [10]. The interval between the peak and end of the T wave on an electrocardiogram (ECG) is called Tp- e interval. Several studies have shown that Tp-e interval can be used as an index of total (transmural, apico-basal, and global) repolarization dispersion [11]. Prolonged Tp-e interval is considered a non-invasive arrhythmogenesis of the development of malignant ventricular arrhythmias [12]. The prolongation of ventricular repolarization parameters QT and QTc duration is accepted as the non-invasive arrhythmogenesis of malignant ventricular arrhythmias [12]. Arterial stiffness has been associated with impaired ventricular repolarization parameters, with possible mechanisms including myocardial and electrophysiological remodeling secondary to increased ventricular load or subendocardial ischemia due to microvascular atherosclerosis in the coronary arteries [13].

This study aimed to compare malignant ventricular arrhythmia markers Tp-e interval and Tp- e/QT and Tp-e/QTc ratios according to CAVI values in patients with regulated arterial hypertension.