mTORC1 signaling pathway regulates tooth repair

Tucker, A. & Sharpe, P. Molecular genetics of tooth morphogenesis and patterning: the right shape in the right place. J. Dent. Res. 78, 826–834 (1999).

Article  PubMed  Google Scholar 

Vilela, A. et al. Dental trauma on primary teeth at different root resorption stages—a dynamic finite element impact analysis of the effect on the permanent tooth germ. Dent. Traumatol. 35, 101–108 (2019).

Article  PubMed  Google Scholar 

Ranka, M., Dhaliwal, H., Albadri, S. & Brown, C. Trauma to the primary dentition and its sequelae. Dent. Update 40, 534–536 (2013).

Article  PubMed  Google Scholar 

Taniguchi, K., Okamura, K., Hayashi, M., Funakoshi, T. & Motokawa, W. The effect of mechanical trauma on the tooth germ of rat molars at various developmental stages: a histopathological study. Endod. Dent. Traumatol. 15, 17–25 (1999).

Article  PubMed  Google Scholar 

Gerritsen, A. E., Allen, P. F., Witter, D. J., Bronkhorst, E. M. & Creugers, N. H. Tooth loss and oral health-related quality of life: a systematic review and meta-analysis. Health Qual. Life Outcomes 8, 126 (2010).

Article  PubMed  PubMed Central  Google Scholar 

Randilini, A., Fujikawa, K. & Shibata, S. Expression, localization and synthesis of small leucine-rich proteoglycans in developing mouse molar tooth germ. Eur. J. Histochem. 64, 3092 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Linton, J., Sohn, B., Yook, J. & Le Geros, R. Effects of calcium phosphate ceramic bone graft materials on permanent teeth eruption in beagles. Cleft. Palate Craniofac. J. 39, 197–207 (2002).

Article  PubMed  Google Scholar 

Su, Y. et al. Genome-wide DNA methylation profile of developing deciduous tooth germ in miniature pigs. BMC Genomics 17, 134 (2016).

Article  PubMed  PubMed Central  Google Scholar 

Tucker, A. S. & Fraser, G. J. Evolution and developmental diversity of tooth regeneration. Semin. Cell Dev. Biol. 25–26, 71–80 (2014).

Article  PubMed  Google Scholar 

Pronobis, M., Zheng, S., Singh, S., Goldman, J. & Poss, K. In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration. eLife 10, e66079 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Kramer, A., Gurdziel, K. & Thummel, R. A comparative analysis of gene and protein expression throughout a full 28-day retinal regeneration time-course in adult zebrafish. Front. Cell. Dev. Biol. 9, 741514 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Qiang, W. et al. Fibroblast growth factor 21 augments autophagy and reduces apoptosis in damaged liver to improve tissue regeneration in zebrafish. Front. Cell. Dev. Biol. 9, 756743 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Brugman, S. The zebrafish as a model to study intestinal inflammation. Dev. Comp. Immunol. 64, 82–92 (2016).

Article  PubMed  Google Scholar 

Kettunen, P. Calcium Imaging in the Zebrafish. Adv. Exp. Med. Biol. 1131, 901–942 (2020).

Article  PubMed  Google Scholar 

Volpe, B. A., Fotino, T. H. & Steiner, A. B. Confocal microscope-based laser ablation and regeneration assay in zebrafish interneuromast cells. J. Vis. Exp. 20, 10.3791/60966 (2020).

Google Scholar 

Arnold, W., Naumova, K., Naumova, E. & Gaengler, P. Comparative qualitative and quantitative assessment of biomineralization of tooth development in man and zebrafish (Danio rerio). Anat. Rec. 291, 571–576 (2008).

Article  Google Scholar 

Van der heyden, C., Wautier, K. & Huysseune, A. Tooth succession in the zebrafish (Danio rerio). Arch. Oral. Biol. 46, 1051–1058 (2001).

Article  PubMed  Google Scholar 

Huysseune, A. Formation of a successional dental lamina in the zebrafish (Danio rerio): support for a local control of replacement tooth initiation. Int. J. Dev. Biol. 50, 637–643 (2006).

Article  PubMed  Google Scholar 

Jernvall, J. & Thesleff, I. Tooth shape formation and tooth renewal: evolving with the same signals. Development 139, 3487–3497 (2012).

Article  PubMed  Google Scholar 

Huysseune, A. & Thesleff, I. Continuous tooth replacement: the possible involvement of epithelial stem cells. Bioessays 26, 665–671 (2010).

Article  Google Scholar 

Pasco-Viel, E. et al. Altered retinoic acid signalling underpins dentition evolution. Proc. R Soc. B Biol. Sci. 282, https://doi.org/10.1098/rspb.2014.2764 (2015).

Zhang, Y. et al. ClC-7 regulates the pattern and early development of craniofacial bone and tooth. Theranostics 9, 1387–1400 (2019).

Article  PubMed  PubMed Central  Google Scholar 

Saxton, R. & Sabatini, D. mTOR signaling in growth, metabolism, and disease. Cell 168, 960–976 (2017).

Article  PubMed  PubMed Central  Google Scholar 

Xie, F., Dai, Q., Liu, X. & Wang, J. Conditional knockout of Raptor/mTORC1 results in dentin malformation. Front. Physiol. 10, 250 (2019).

Article  PubMed  PubMed Central  Google Scholar 

Xiong, Z. et al. Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis. Biol. Reprod. 99, 1289–1302 (2018).

Article  PubMed  Google Scholar 

Moustafa-Kamal, M. et al. The mTORC1/S6K/PDCD4/eIF4A axis determines outcome of mitotic arrest. Cell Rep. 33, 108230 (2020).

Article  PubMed  Google Scholar 

Nie, X. et al. mTOR acts as a pivotal signaling hub for neural crest cells during craniofacial development. PLoS Genet. 14, e1007491 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Nie, X., Zheng, J., Cruciger, M., Yang, P. & Mao, J. J. mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev. Biol. 467, 77–87 (2020).

Article  PubMed  Google Scholar 

Kim, J., Baker, J., Nor, J. & Hill, E. mTor plays an important role in odontoblast differentiation. J. Endod. 37, 1081–1085 (2011).

Article  PubMed  Google Scholar 

Zhao, H. et al. Secretion of shh by a neurovascular bundle niche supports mesenchymal stem cell homeostasis in the adult mouse incisor. Cell Stem Cell 14, 160–173 (2014).

Article  PubMed  PubMed Central  Google Scholar 

Curado, S., Stainier, D. & Anderson, R. Nitroreductase-mediated cell/tissue ablation in zebrafish: a spatially and temporally controlled ablation method with applications in developmental and regeneration studies. Nat. Protoc. 3, 948–954 (2008).

Article  PubMed  PubMed Central  Google Scholar 

Curado, S. et al. Conditional targeted cell ablation in zebrafish: a new tool for regeneration studies. Dev. Dyn. 236, 1025–1035 (2007).

Article  PubMed  Google Scholar 

Jackman, W. & Stock, D. Transgenic analysis of Dlx regulation in fish tooth development reveals evolutionary retention of enhancer function despite organ loss. Proc. Natl Acad. Sci. USA 103, 19390–19395 (2006).

Article  PubMed  PubMed Central  Google Scholar 

Borday-Birraux, V. et al. Expression of Dlx genes during the development of the zebrafish pharyngeal dentition: evolutionary implications. Evol. Dev. 8, 130–141 (2006).

Article  PubMed  Google Scholar 

He, J., Lu, H., Zou, Q. & Luo, L. Regeneration of liver after extreme hepatocyte loss occurs mainly via biliary transdifferentiation in zebrafish. Gastroenterology 146, 789–800.e788 (2014).

Article  PubMed  Google Scholar 

Kawasaki, K. et al. Coevolution of enamel, ganoin, enameloid, and their matrix SCPP genes in osteichthyans. iScience 24, 102023 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Zhou, C., Zheng, X. & Yang, D. Knockout fth1b affects early mineralization of zebrafish pharyngeal teeth. W-Chn. J. Stomat. 39, 32–37 (2021).

Google Scholar 

Bensimon-Brito, A. et al. Revisiting in vivo staining with alizarin red S—a valuable approach to analyse zebrafish skeletal mineralization during development and regeneration. BMC Dev. Biol. 16, 2 (2016).

Article  PubMed  PubMed Central  Google Scholar 

Barrientos, S., Stojadinovic, O., Golinko, M. S., Brem, H. & Tomic-Canic, M. Growth factors and cytokines in wound healing. Wound Repair Regen. 16, 585–601 (2008).

Article  PubMed  Google Scholar 

Gibert, Y., Samarut, E., Ellis, M., Jackman, W. & Laudet, V. The first formed tooth serves as a signalling centre to induce the formation of the dental row in zebrafish. Proc. Biol. Sci. 286, 20190401 (2019).

PubMed  PubMed Central  Google Scholar 

Payne, T., Skobe, Z. & Yelick, P. Regulation of tooth development by the novel type I TGFbeta family member receptor Alk8. J. Dent. Res. 80, 1968–1973 (2001).

Article  PubMed  Google Scholar 

Jackman, W., Draper, B. & Stock, D. Fgf signaling is required for zebrafish tooth development. Dev. Biol. 274, 139–157 (2004).

Article  PubMed  Google Scholar 

留言 (0)

沒有登入
gif