New Recommendations of a Height-Based Dosing Regimen of Tobramycin for Cystic Fibrosis in Adults: A Population Pharmacokinetic Analysis

*Faculty of Pharmacy, Université de Montréal;

‡Pharmacy Department, Royal Victoria Hospital, McGill University Health Centre;

†Laboratoire STP2, Faculty of Pharmacy, Université de Montréal; and

§Adult Cystic Fibrosis Clinic, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada.

Correspondence: Kévin Koloskoff, PharmD, Pavillon Jean-Coutu, 2940 Chemin de Polytechnique, Montréal H3T 1J4, Canada (e-mail: [email protected]).

Supported in part by the Canada Foundation for Innovation. Amélie Marsot acknowledges the support from the Fonds de Recherche du Québec-Santé (FRQS) Research Scholars—Junior 1 (Young Researcher Establishment) Career Scholarship. Kévin Koloskoff received support from the AMIDEX Foundation.

The authors declare no conflict of interest.

This study was approved by the MUHC Ethics Committee (2020–6351) and the University of Montreal (CERC-20-027-D).

Data are available upon reasonable request.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.drug-monitoring.com).

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