Gas gangrene caused by spontaneous Clostridium septicum infection: A case study

Spontaneous Clostridium septicum gas gangrene is a rare opportunistic infection with a high mortality rate and is often associated with underlying immunosuppression or malignancy [[1], [2], [3]]. It is a gram positive, anaerobic bacterium. Its main virulence factor is the ability to produce alpha-toxin, which is considered the main cause of C. septicum induced atraumatic myonecrosis [4]. It usually gains access into the bloodstream or tissues by penetrating the intestinal wall through a mucosal defect, most commonly the caecum or the colon ascendens [2]. We present a case of spontaneous C. septicum gas gangrene in a previously otherwise healthy individual with a history of robot assisted renal resection.

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