Traumatic MicroRNAs: Deconvolving the Signal After Severe Traumatic Brain Injury

Alosco ML, Koerte IK, Tripodis Y, Mariani M, Chua AS, Jarnagin J, Rahimpour Y, Puzo C, Healy RC, Martin B, Chaisson CE, Cantu RC, Au R, McClean M, McKee AC, Lin AP, Shenton ME, Killiany RJ, Stern RA (2018) White matter signal abnormalities in former National Football League players. Alzheimers Dement (amst) 10:56–65. https://doi.org/10.1016/j.dadm.2017.10.003

Article  PubMed  Google Scholar 

Atif H, Hicks SD (2019) A review of microRNA biomarkers in traumatic brain injury. J Exp Neurosci 13:1179069519832286. https://doi.org/10.1177/1179069519832286

Article  PubMed  PubMed Central  Google Scholar 

Barbagallo C, Mostile G, Baglieri G, Giunta F, Luca A, Raciti L, Zappia M, Purrello M, Ragusa M, Nicoletti A (2020) Specific signatures of serum mirnas as potential biomarkers to discriminate clinically similar neurodegenerative and vascular-related diseases. Cell Mol Neurobiol 40:531–546. https://doi.org/10.1007/s10571-019-00751-y

Article  CAS  PubMed  Google Scholar 

Bartolotti N, Bennett DA, Lazarov O (2016) Reduced pCREB in Alzheimer’s disease prefrontal cortex is reflected in peripheral blood mononuclear cells. Mol Psychiatry 21:1158–1166. https://doi.org/10.1038/mp.2016.111

Article  CAS  PubMed  PubMed Central  Google Scholar 

van den Berg MMJ, Krauskopf J, Ramaekers JG, Kleinjans JCS, Prickaerts J, Briede JJ (2020) Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders. Prog Neurobiol 185:101732. https://doi.org/10.1016/j.pneurobio.2019.101732

Article  PubMed  Google Scholar 

Bhomia M, Balakathiresan NS, Wang KK, Papa L, Maheshwari RK (2016) A panel of serum MiRNA biomarkers for the diagnosis of severe to mild traumatic brain injury in humans. Sci Rep 6:28148. https://doi.org/10.1038/srep28148

Article  CAS  PubMed  PubMed Central  Google Scholar 

Blennow K, Brody DL, Kochanek PM, Levin H, McKee A, Ribbers GM, Yaffe K, Zetterberg H (2016) Traumatic brain injuries. Nat Rev Dis Primers 2:16084. https://doi.org/10.1038/nrdp.2016.84

Article  PubMed  Google Scholar 

Brown KR, Otasek D, Ali M, McGuffin MJ, Xie W, Devani B, Toch IL, Jurisica I (2009) NAViGaTOR: network analysis, visualization and graphing toronto. Bioinformatics 25:3327–3329. https://doi.org/10.1093/bioinformatics/btp595

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bryan MR, Bowman AB (2017) Manganese and the insulin-IGF signaling network in Huntington’s disease and other neurodegenerative disorders. Adv Neurobiol 18:113–142. https://doi.org/10.1007/978-3-319-60189-2_6

Article  PubMed  PubMed Central  Google Scholar 

Chandran R, Sharma A, Bhomia M, Balakathiresan NS, Knollmann-Ritschel BE, Maheshwari RK (2017) Differential expression of microRNAs in the brains of mice subjected to increasing grade of mild traumatic brain injury. Brain Inj 31:106–119. https://doi.org/10.1080/02699052.2016.1213420

Article  PubMed  Google Scholar 

Chang CY, Liang MZ, Wu CC, Huang PY, Chen HI, Yet SF, Tsai JW, Kao CF, Chen L (2020) WNT3A promotes neuronal regeneration upon traumatic brain injury. Int J Mol Sci 21:1463. https://doi.org/10.3390/ijms21041463

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cheng L, Doecke JD, Sharples RA, Villemagne VL, Fowler CJ, Rembach A, Martins RN, Rowe CC, Macaulay SL, Masters CL, Hill AF, Australian Imaging B, Lifestyle Research G (2015) Prognostic serum miRNA biomarkers associated with Alzheimer’s disease shows concordance with neuropsychological and neuroimaging assessment. Mol Psychiatry 20:1188–1196. https://doi.org/10.1038/mp.2014.127

Article  CAS  PubMed  Google Scholar 

Chiaretti A, Antonelli A, Genovese O, Pezzotti P, Rocco CD, Viola L, Riccardi R (2008) Nerve growth factor and doublecortin expression correlates with improved outcome in children with severe traumatic brain injury. J Trauma 65:80–85. https://doi.org/10.1097/TA.0b013e31805f7036

Article  CAS  PubMed  Google Scholar 

Chio CC, Chang CP, Lin MT, Su FC, Yang CZ, Tseng HY, Liu ZM, Huang HS (2014) Involvement of TG-interacting factor in microglial activation during experimental traumatic brain injury. J Neurochem 131:816–824. https://doi.org/10.1111/jnc.12971

Article  CAS  PubMed  Google Scholar 

Cogswell JP, Ward J, Taylor IA, Waters M, Shi Y, Cannon B, Kelnar K, Kemppainen J, Brown D, Chen C, Prinjha RK, Richardson JC, Saunders AM, Roses AD, Richards CA (2008) Identification of miRNA changes in Alzheimer’s disease brain and CSF yields putative biomarkers and insights into disease pathways. J Alzheimers Dis 14:27–41. https://doi.org/10.3233/jad-2008-14103

Article  CAS  PubMed  Google Scholar 

Corps KN, Roth TL, McGavern DB (2015) Inflammation and neuroprotection in traumatic brain injury. JAMA Neurol 72:355–362. https://doi.org/10.1001/jamaneurol.2014.3558

Article  PubMed  PubMed Central  Google Scholar 

Delic V, Beck KD, Pang KCH, Citron BA (2020) Biological links between traumatic brain injury and Parkinson’s disease. Acta Neuropathol Commun 8:45. https://doi.org/10.1186/s40478-020-00924-7

Article  CAS  PubMed  PubMed Central  Google Scholar 

Denk J, Boelmans K, Siegismund C, Lassner D, Arlt S, Jahn H (2015) MicroRNA profiling of CSF reveals potential biomarkers to detect Alzheimer’s disease. PLoS ONE 10:e0126423. https://doi.org/10.1371/journal.pone.0126423

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dewan MC, Rattani A, Gupta S, Baticulon RE, Hung YC, Punchak M, Agrawal A, Adeleye AO, Shrime MG, Rubiano AM, Rosenfeld JV, Park KB (2019) Estimating the global incidence of traumatic brain injury. J Neurosurg 130:1080–1097. https://doi.org/10.3171/2017.10.JNS17352

Article  Google Scholar 

Di Pietro V, Ragusa M, Davies D, Su Z, Hazeldine J, Lazzarino G, Hill LJ, Crombie N, Foster M, Purrello M, Logan A, Belli A (2017) MicroRNAs as novel biomarkers for the diagnosis and prognosis of mild and severe traumatic brain injury. J Neurotrauma 34:1948–1956. https://doi.org/10.1089/neu.2016.4857

Article  PubMed  Google Scholar 

Di Pietro V, Yakoub KM, Scarpa U, Di Pietro C, Belli A (2018) MicroRNA signature of traumatic brain injury: from the biomarker discovery to the point-of-care. Front Neurol 9:429. https://doi.org/10.3389/fneur.2018.00429

Article  PubMed  PubMed Central  Google Scholar 

Edwards KA, Motamedi V, Osier ND, Kim HS, Yun S, Cho YE, Lai C, Dell KC, Carr W, Walker P, Ahlers S, LoPresti M, Yarnell A, Tschiffley A, Gill JM (2020) A Moderate blast exposure results in dysregulated gene network activity related to cell death, survival, structure, and metabolism. Front Neurol 11:91. https://doi.org/10.3389/fneur.2020.00091

Article  PubMed  PubMed Central  Google Scholar 

Farr SA, Niehoff ML, Kumar VB, Roby DA, Morley JE (2019) Inhibition of glycogen synthase kinase 3beta as a treatment for the prevention of cognitive deficits after a traumatic brain injury. J Neurotrauma 36:1869–1875. https://doi.org/10.1089/neu.2018.5999

Article  PubMed  Google Scholar 

Forlenza OV, Diniz BS, Talib LL, Mendonca VA, Ojopi EB, Gattaz WF, Teixeira AL (2009) Increased serum IL-1beta level in Alzheimer’s disease and mild cognitive impairment. Dement Geriatr Cogn Disord 28:507–512. https://doi.org/10.1159/000255051

Article  CAS  PubMed  Google Scholar 

Gao W, Li F, Zhou Z, Xu X, Wu Y, Zhou S, Yin D, Sun D, Xiong J, Jiang R, Zhang J (2017) IL-2/Anti-IL-2 complex attenuates inflammation and BBB disruption in mice subjected to traumatic Brain injury. Front Neurol 8:281. https://doi.org/10.3389/fneur.2017.00281

Article  PubMed  PubMed Central  Google Scholar 

Gardner RC, Burke JF, Nettiksimmons J, Goldman S, Tanner CM, Yaffe K (2015) Traumatic brain injury in later life increases risk for Parkinson disease. Ann Neurol 77:987–995. https://doi.org/10.1002/ana.24396

Article  PubMed  PubMed Central  Google Scholar 

Gardner RC, Byers AL, Barnes DE, Li Y, Boscardin J, Yaffe K (2018) Mild TBI and risk of Parkinson disease: a chronic effects of neurotrauma consortium study. Neurology 90:e1771–e1779. https://doi.org/10.1212/WNL.0000000000005522

Article  PubMed  PubMed Central  Google Scholar 

Golz C, Kirchhoff FP, Westerhorstmann J, Schmidt M, Hirnet T, Rune GM, Bender RA, Schafer MKE (2019) Sex hormones modulate pathogenic processes in experimental traumatic brain injury. J Neurochem 150:173–187. https://doi.org/10.1111/jnc.14678

Article  CAS  PubMed  Google Scholar 

Gu Q, Cuevas E, Raymick J, Kanungo J, Sarkar S (2020) Downregulation of 14–3-3 Proteins in Alzheimer’s disease. Mol Neurobiol 57:32–40. https://doi.org/10.1007/s12035-019-01754-y

Article  CAS  PubMed  Google Scholar 

Guo Z, Cupples LA, Kurz A, Auerbach SH, Volicer L, Chui H, Green RC, Sadovnick AD, Duara R, DeCarli C, Johnson K, Go RC, Growdon JH, Haines JL, Kukull WA, Farrer LA (2000) Head injury and the risk of AD in the MIRAGE study. Neurology 54:1316–1323. https://doi.org/10.1212/wnl.54.6.1316

Article  CAS  PubMed  Google Scholar 

Guo R, Fan G, Zhang J, Wu C, Du Y, Ye H, Li Z, Wang L, Zhang Z, Zhang L, Zhao Y, Lu Z (2017) A 9-microRNA signature in serum serves as a noninvasive biomarker in early diagnosis of Alzheime’’s disease. J Alzheimers Dis 60:1365–1377. https://doi.org/10.3233/JAD-170343

Article  CAS  PubMed  Google Scholar 

He XY, Dan QQ, Wang F, Li YK, Fu SJ, Zhao N, Wang TH (2018) Protein network analysis of the serum and their functional implication in patients subjected to traumatic brain injury. Front Neurosci 12:1049. https://doi.org/10.3389/fnins.2018.01049

Article  PubMed  Google Scholar 

Hu Z, Yu D, Almeida-Suhett C, Tu K, Marini AM, Eiden L, Braga MF, Zhu J, Li Z (2012) Expression of miRNAs and their cooperative regulation of the pathophysiology in traumatic brain injury. PLoS ONE 7:e39357. https://doi.org/10.1371/journal.pone.0039357

Article  CAS  PubMed  PubMed Central  Google Scholar 

留言 (0)

沒有登入
gif