Progressive Degeneration and Adaptive Excitability in Dopamine D1 and D2 Receptor-Expressing Striatal Neurons Exposed to HIV-1 Tat and Morphine

Abudukeyoumu N, Hernandez-Flores T, Garcia-Munoz M, Arbuthnott GW (2019) Cholinergic modulation of striatal microcircuits. Eur J Neurosci 49(5):604–622. https://doi.org/10.1111/ejn.13949

Article  PubMed  Google Scholar 

Ade KK, Wan Y, Chen M, Gloss B, Calakos N (2011) An improved BAC transgenic fluorescent reporter line for sensitive and specific identification of striatonigral medium spiny neurons. Front Syst Neurosci 5:32. https://doi.org/10.3389/fnsys.2011.00032

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ahlijanian MK, Barrezueta NX, Williams RD, Jakowski A, Kowsz KP, McCarthy S, Coskran T, Carlo A, Seymour PA, Burkhardt JE (2000) Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5. Proc Natl Acad Sci 97(6):2910–2915

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aksenov MY, Aksenova MV, Silvers JM, Mactutus CF, Booze RM (2008) Different effects of selective dopamine uptake inhibitors, GBR 12909 and WIN 35428, on HIV-1 Tat toxicity in rat fetal midbrain neurons. Neurotoxicology 29(6):971–977. https://doi.org/10.1016/j.neuro.2008.06.003

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aksenova MV, Silvers JM, Aksenov MY, Nath A, Ray PD, Mactutus CF, Booze RM (2006) HIV-1 Tat neurotoxicity in primary cultures of rat midbrain fetal neurons: changes in dopamine transporter binding and immunoreactivity. Neurosci Lett 395(3):235–239. https://doi.org/10.1016/j.neulet.2005.10.095

Article  CAS  PubMed  Google Scholar 

Albin RL, Young AB, Penney JB (1989) The functional anatomy of basal ganglia disorders. Trends Neurosci 12(10):366–375

Article  CAS  PubMed  Google Scholar 

Al-Harthi L, Joseph J, Nath A (2018) Astrocytes as an HIV CNS reservoir: highlights and reflections of an NIMH-sponsored symposium. J Neurovirol 24(6):665–669. https://doi.org/10.1007/s13365-018-0691-8

Article  Google Scholar 

Alonso AC, Grundke-Iqbal I, Iqbal K (1996) Alzheimer’s disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules. Nat Med 2(7):783–787. https://doi.org/10.1038/nm0796-783

Article  CAS  PubMed  Google Scholar 

Anthony IC, Ramage SN, Carnie FW, Simmonds P, Bell JE (2006) Accelerated Tau deposition in the brains of individuals infected with human immunodeficiency virus-1 before and after the advent of highly active anti-retroviral therapy. Acta Neuropathol 111(6):529–538. https://doi.org/10.1007/s00401-006-0037-0

Article  CAS  PubMed  Google Scholar 

Atwood BK, Kupferschmidt DA, Lovinger DM (2014) Opioids induce dissociable forms of long-term depression of excitatory inputs to the dorsal striatum. Nat Neurosci 17(4):540–548. https://doi.org/10.1038/nn.3652

Article  CAS  PubMed  PubMed Central  Google Scholar 

Banghart MR, Neufeld SQ, Wong NC, Sabatini BL (2015) Enkephalin disinhibits µ opioid receptor-rich striatal patches via δ opioid receptors. Neuron 88(6):1227–1239. https://doi.org/10.1016/j.neuron.2015.11.010

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barbour AJ, Hauser KF, McQuiston AR, Knapp PE (2020) HIV and opiates dysregulate K+-Cl−-cotransporter 2 (KCC2) to cause GABAergic dysfunction in primary human neurons and Tat-transgenic mice. Neurobiol Dis 141:104878

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barbour AJ, Nass SR, Hahn YK, Hauser KF, Knapp PE (2021) Restoration of KCC2 membrane localization in striatal dopamine D2 receptor-expressing medium spiny neurons rescues locomotor deficits in HIV Tat-transgenic mice. ASN Neuro 13:17590914211022088. https://doi.org/10.1177/17590914211022089

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bariselli S, Fobbs WC, Creed MC, Kravitz AV (2019) A competitive model for striatal action selection. Brain Res 1713:70–79. https://doi.org/10.1016/j.brainres.2018.10.009

Article  CAS  PubMed  Google Scholar 

Becker JT, Sanders J, Madsen SK, Ragin A, Kingsley L, Maruca V, Cohen B, Goodkin K, Martin E, Miller EN, Sacktor N, Alger JR, Barker PB, Saharan P, Carmichael OT, Thompson PM, Multicenter AIDS Cohort Study (2011) Subcortical brain atrophy persists even in HAART-regulated HIV disease. Brain Imaging Behav 5(2):77–85. https://doi.org/10.1007/s11682-011-9113-8

Article  PubMed  PubMed Central  Google Scholar 

Berger JR, Arendt G (2000) HIV dementia: the role of the basal ganglia and dopaminergic systems. J Psychopharmacol (oxford, England) 14(3):214–221. https://doi.org/10.1177/026988110001400304

Article  CAS  Google Scholar 

Berger JR, Nath A (1997) HIV dementia and the basal ganglia. Intervirology 40(2–3):122–131. https://doi.org/10.1159/000150539

Article  CAS  PubMed  Google Scholar 

Birdsong WT, Jongbloets BC, Engeln KA, Wang D, Scherrer G, Mao T (2019) Synapse-specific opioid modulation of thalamo-cortico-striatal circuits. Elife. https://doi.org/10.7554/eLife.45146

Article  PubMed  PubMed Central  Google Scholar 

Brailoiu GC, Deliu E, Barr JL, Console-Bram LM, Ciuciu AM, Abood ME, Unterwald EM, Brailoiu E (2017) HIV Tat excites D1 receptor-like expressing neurons from rat nucleus accumbens. Drug Alcohol Depend 178:7–14. https://doi.org/10.1016/j.drugalcdep.2017.04.015

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brew BJ, Pemberton L, Blennow K, Wallin A, Hagberg L (2005) CSF amyloid β42 and tau levels correlate with AIDS dementia complex. Neurology 65(9):1490. https://doi.org/10.1212/01.wnl.0000183293.95787.b7

Article  CAS  PubMed  Google Scholar 

Bruce-Keller AJ, Turchan-Cholewo J, Smart EJ, Geurin T, Chauhan A, Reid R, Xu R, Nath A, Knapp PE, Hauser KF (2008) Morphine causes rapid increases in glial activation and neuronal injury in the striatum of inducible HIV-1 Tat transgenic mice. Glia 56(13):1414–1427. https://doi.org/10.1002/glia.20708

Article  PubMed  PubMed Central  Google Scholar 

Buch S, Periyasamy P, Thangaraj A, Sil S, Chivero ET, Tripathi A (2020) Opioid-mediated HIV-1 immunopathogenesis. J Neuroimmune Pharmacol 15(4):628–642. https://doi.org/10.1007/s11481-020-09960-5

Article  PubMed  PubMed Central  Google Scholar 

Buzhdygan T, Lisinicchia J, Patel V, Johnson K, Neugebauer V, Paessler S, Jennings K, Gelman B (2016) Neuropsychological, neurovirological and neuroimmune aspects of abnormal GABAergic transmission in HIV infection. J Neuroimmune Pharmacol 11(2):279–293. https://doi.org/10.1007/s11481-016-9652-2

Article  PubMed  PubMed Central  Google Scholar 

Carpenter AE, Jones TR, Lamprecht MR, Clarke C, Kang IH, Friman O, Guertin DA, Chang JH, Lindquist RA, Moffat J, Golland P, Sabatini DM (2006) Cell Profiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol 7(10):R100. https://doi.org/10.1186/gb-2006-7-10-r100

Article  CAS  PubMed  PubMed Central  Google Scholar 

Castelo JMB, Courtney MG, Melrose RJ, Stern CE (2007) Putamen hypertrophy in nondemented patients with human immunodeficiency virus infection and cognitive compromise. Arch Neurol 64(9):1275–1280. https://doi.org/10.1001/archneur.64.9.1275

Article  PubMed  Google Scholar 

Chang L, Wang GJ, Volkow ND, Ernst T, Telang F, Logan J, Fowler JS (2008) Decreased brain dopamine transporters are related to cognitive deficits in HIV patients with or without cocaine abuse. Neuroimage 42(2):869–878. https://doi.org/10.1016/j.neuroimage.2008.05.011

Article  PubMed  Google Scholar 

Chilunda V, Calderon TM, Martinez-Aguado P, Berman JW (2019) The impact of substance abuse on HIV-mediated neuropathogenesis in the current ART era. Brain Res 1724:146426. https://doi.org/10.1016/j.brainres.2019.146426

Article  CAS  PubMed  PubMed Central  Google Scholar 

Day M, Wang Z, Ding J, An X, Ingham CA, Shering AF, Wokosin D, Ilijic E, Sun Z, Sampson AR, Mugnaini E, Deutch AY, Sesack SR, Arbuthnott GW, Surmeier DJ (2006) Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models. Nat Neurosci 9(2):251–259. https://doi.org/10.1038/nn1632

Article  CAS  PubMed  Google Scholar 

DeLong MR (1990) Primate models of movement disorders of basal ganglia origin. Trends Neurosci 13(7):281–285. https://doi.org/10.1016/0166-2236(90)90110-V

Article  CAS  PubMed  Google Scholar 

Dickens AM, Yoo SW, Chin AC, Xu J, Johnson TP, Trout AL, Hauser KF, Haughey NJ (2017) Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging. Sci Rep 7(1):7748. https://doi.org/10.1038/s41598-017-07570-5

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dobbs LK, Kaplan AR, Lemos JC, Matsui A, Rubinstein M, Alvarez VA (2016) Dopamine regulation of lateral inhibition between striatal neurons gates the stimulant actions of cocaine. Neuron 90(5):1100–1113. https://doi.org/10.1016/j.neuron.2016.04.031

Article  CAS  PubMed  PubMed Central  Google Scholar 

Duncan MJ, Bruce-Keller AJ, Conner C, Knapp PE, Xu R, Nath A, Hauser KF (2008) Effects of chronic expression of the HIV-induced protein, transactivator of transcription, on circadian activity rhythms in mice, with or without morphine. Am J Physiol Regul Integr Comp Physiol 295(5):R1680-1687. https://doi.org/10.1152/ajpregu.90496.2008

Article  CAS  PubMed  PubMed Central  Google Scholar 

El-Hage N, Gurwell JA, Singh IN, Knapp PE, Nath A, Hauser KF (2005) Synergistic increases in intracellular Ca2+, and the release of MCP-1, RANTES, and IL-6 by astrocytes treated with opiates and HIV-1 Tat. Glia 50(2):91–106. https://doi.org/10.1002/glia.20148

Article  PubMed 

留言 (0)

沒有登入
gif