Insight into the mechanism behind oral bioavailability-enhancement by nanosuspensions through combined dissolution/permeation studies

Keywords

Dual asymmetric centrifugation

Dissolution/permeation

Nanosuspension

Nanomilling

Poorly soluble drugs

Supersaturation

AbbreviationsAPI

active pharmaceutical ingredient

DSC

differential scanning calorimetry

DLS

dynamic light scattering

HP-β-CD

2-hydroxypropyl-β-cyclodextrin

IVIVC

in vivo/in vitro correlation

XRPD

x-ray powder diffraction

© 2023 The Author(s). Published by Elsevier B.V.

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