Impact of protocatechuic acid on alleviation of pulmonary damage induced by cyclophosphamide targeting peroxisome proliferator activator receptor, silent information regulator type-1, and fork head box protein in rats

Aladaileh SH, Abukhalil MH, Saghir SA et al (2019) Galangin activates Nrf2 signaling and attenuates oxidative damage, inflammation, and apoptosis in a rat model of cyclophosphamide-induced hepatotoxicity. Biomolecules 9(8):346

Article  CAS  PubMed  PubMed Central  Google Scholar 

AlHaithloul HA, Alotaibi MF, Bin-Jumah M, Elgebaly H, Mahmoud AM (2019) Olea europaea leaf extract up-regulates Nrf2/ARE/HO-1 signaling and attenuates cyclophosphamide-induced oxidative stress, inflammation and apoptosis in rat kidney. Biomed Pharmacother 111:676–685

Article  CAS  PubMed  Google Scholar 

Alsemeh AE, Abdullah DM (2022) Protective effect of alogliptin against cyclophosphamide-induced lung toxicity in rats: Impact on PI3K/Akt/FoxO1 pathway and downstream inflammatory cascades. Cell Tissue Res 388(2):417–438

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alsharif KF, Almalki AA, Alsanie WF et al (2021) Protocatechuic acid attenuates lipopolysaccharide-induced septic lung injury in mice: The possible role through suppressing oxidative stress, inflammation and apoptosis. J Food Biochem 45(10):e13915

Article  CAS  PubMed  Google Scholar 

Arcidiacono B, Chiefari E, Messineo S et al (2018) HMGA1 is a novel transcriptional regulator of the FoxO1 gene. Endocrine 60(1):56–64

Article  CAS  PubMed  Google Scholar 

Bai X, Fan L, He T et al (2015) SIRT1 protects rat lung tissue against severe burn-induced remote ALI by attenuating the apoptosis of PMVECs via p38 MAPK signaling. Sci Rep 5(1):1–13

Google Scholar 

Basha M, Salama A, Noshi SH (2020) Soluplus® based solid dispersion as fast disintegrating tablets: a combined experimental approach for enhancing the dissolution and antiulcer efficacy of famotidine. Drug Dev Ind Pharm 46(2):253–263

Article  CAS  PubMed  Google Scholar 

Blondonnet R, Constantin J-M, Sapin V, Jabaudon M (2016) A pathophysiologic approach to biomarkers in acute respiratory distress syndrome. Dis Markers 2016:3501373

Article  PubMed  PubMed Central  Google Scholar 

Carleton HM, Drury RAB, Wallington EA (1980) Carleton’s histological technique. Oxford University Press, USA

Google Scholar 

Castillo R, Loza RC, Romero-Dapueto C (2015) Suppl 2: M2: pathophysiological approaches of acute respiratory distress syndrome: novel bases for study of lung injury. Open Respir Med J 9:83

Article  CAS  PubMed  PubMed Central  Google Scholar 

Corton JC, Anderson SP, Stauber A (2000) Central role of peroxisome proliferator-activated receptors in the actions of peroxisome proliferators. Annu Rev Pharmacol Toxicol 40:491

Article  CAS  PubMed  Google Scholar 

Delerive P, De Bosscher K, Besnard S et al (1999) Peroxisome proliferator-activated receptor α negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-κB and AP-1. J Biol Chem 274(45):32048–32054

Article  CAS  PubMed  Google Scholar 

Ding Y-W, Zhao G-J, Li X-L et al (2016) SIRT1 exerts protective effects against paraquat-induced injury in mouse type II alveolar epithelial cells by deacetylating NRF2 in vitro. Int J Mol Med 37(4):1049–1058

Article  CAS  PubMed  Google Scholar 

Dong P, Xia L, Hu L, Yang K, Wang H, Ye P (2021) Runjing decoction alleviated cyclophosphamide-induced oligoasthenospermia rats by inhibiting cell apoptosis via RXFP1/AKT/FOXO1 pathway. Andrologia 53(11):e14216

Article  CAS  PubMed  Google Scholar 

Elrashidy RA, Hasan RA (2021) Cilostazol preconditioning alleviates cyclophosphamide-induced cardiotoxicity in male rats: mechanistic insights into SIRT1 signaling pathway. Life Sci 266:118822

Article  CAS  PubMed  Google Scholar 

Emadi A, Jones RJ, Brodsky RA (2009) Cyclophosphamide and cancer: golden anniversary. Nat Rev Clin Oncol 6(11):638–647

Article  CAS  PubMed  Google Scholar 

Gervois P, Fruchart J-C, Delerive P, Staels B (2000) Induction of IκBα expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-α activators. J Biol Chem 275(47):36703–36707

Article  PubMed  Google Scholar 

Ghoreschi K, Laurence A, Yang X-P et al (2010) Generation of pathogenic TH17 cells in the absence of TGF-β signalling. Nature 467(7318):967–971

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gonçalves-de-Albuquerque SdC, Pessoa-e-Silva R, Trajano-Silva LA et al (2017) The equivocal role of Th17 cells and neutrophils on immunopathogenesis of leishmaniasis. Front Immunol 8:1437

Article  PubMed  PubMed Central  Google Scholar 

Hamsa T, Kuttan G (2010) Ipomoea obscura ameliorates cyclophosphamide-induced toxicity by modulating the immune system and levels of proinflammatory cytokine and GSH. Can J Physiol Pharmacol 88(11):1042–1053

Article  CAS  PubMed  Google Scholar 

Haubitz M (2007) Acute and long-ter toxicity of cyclophosphamide. Transplantationsmedizin 19(2):26

Google Scholar 

Hsu C-C, Hsu C-L, Tsai S-E, Fu TY-C, Yen G-C (2009) Protective effect of Millettia reticulata Benth against CCl4-induced hepatic damage and inflammatory action in rats. J Med Food 12(4):821–828

Article  CAS  PubMed  Google Scholar 

Ibitoye O, Ajiboye T (2020) Protocatechuic acid protects against menadione-induced liver damage by up-regulating nuclear erythroid-related factor 2. Drug Chem Toxicol 43(6):567–573

Article  CAS  PubMed  Google Scholar 

Ishii H, Ishibashi M, Takayama M, Nishida T, Yoshida M (2000) The role of cytokine-induced neutrophil chemoattractant-1 in neutrophil-mediated remote lung injury after intestinal ischaemia/reperfusion in rats. Respirology 5(4):325–331

Article  CAS  PubMed  Google Scholar 

Je J-Y, Lee D-B (2015) Nelumbo nucifera leaves protect hydrogen peroxide-induced hepatic damage via antioxidant enzymes and HO-1/Nrf2 activation. Food Funct 6(6):1911–1918

Article  CAS  PubMed  Google Scholar 

Kaewmool C, Kongtawelert P, Phitak T, Pothacharoen P, Udomruk S (2020) Protocatechuic acid inhibits inflammatory responses in LPS-activated BV2 microglia via regulating SIRT1/NF-κB pathway contributed to the suppression of microglial activation-induced PC12 cell apoptosis. J Neuroimmunol 341:577164

Article  CAS  PubMed  Google Scholar 

Kaplan JM, Cook JA, Hake PW, O’Connor M, Burroughs TJ, Zingarelli B (2005) 15-Deoxy-Δ12, 14-prostaglandin J2 (15d-PGJ2), a peroxisome proliferator activated receptor γ ligand, reduces tissue leukosequestration and mortality in endotoxic shock. Shock 24(1):59–65

Article  CAS  PubMed  Google Scholar 

Kim M-k, Shin HM, Jung H et al (2017) Comparison of pancreatic beta cells and alpha cells under hyperglycemia: Inverse coupling in pAkt-FoxO1. Diabetes Res Clin Pract 131:1–11

Article  CAS  PubMed  Google Scholar 

Krzysztoforska K, Piechal A, Blecharz-Klin K et al (2019) Administration of protocatechuic acid affects memory and restores hippocampal and cortical serotonin turnover in rat model of oral D-galactose-induced memory impairment. Behav Brain Res 368:111896. https://doi.org/10.1016/j.bbr.2019.04.010

Article  CAS  PubMed  Google Scholar 

Kurundkar D, Kurundkar AR, Bone NB et al (2019) SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury. JCI Insight. https://doi.org/10.1172/jci.insight.120722

Article  PubMed  PubMed Central  Google Scholar 

Lee Y, Jeong GS, Kim KM, Lee W, Bae JS (2018) Cudratricusxanthone A attenuates sepsis-induced liver injury via SIRT1 signaling. J Cell Physiol 233(7):5441–5446

Article  CAS  PubMed  Google Scholar 

Lende AB, Kshirsagar AD, Deshpande AD et al (2011) Anti-inflammatory and analgesic activity of protocatechuic acid in rats and mice. Inflammopharmacology 19(5):255–263

Article  CAS  PubMed  Google Scholar 

Li T, Zhang J, Feng J et al (2013) Resveratrol reduces acute lung injury in a LPS-induced sepsis mouse model via activation of Sirt1. Mol Med Rep 7(6):1889–1895

Article  CAS  PubMed  Google Scholar 

Liu C-L, Wang J-M, Chu C-Y, Cheng M-T, Tseng T-H (2002) In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity. Food Chem Toxicol 40(5):635–641

Article  CAS  PubMed  Google Scholar 

Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT method. Methods 25(4):402–408

Article  CAS  PubMed  Google Scholar 

Mahlooji MA, Heshmati A, Kheiripour N et al (2022) Evaluation of protective effects of curcumin and nanocurcumin on aluminium phosphide-induced subacute lung injury in rats: modulation of oxidative stress through SIRT1/FOXO3 signalling pathway. Drug Res 72(02):100–108

Article  CAS  Google Scholar 

Molehin OR, Adeyanju AA, Adefegha SA, Oyeyemi AO, Idowu KA (2019) Protective mechanisms of protocatechuic acid against doxorubicin-induced nephrotoxicity in rat model. J Basic Clin Physiol Pharmacol. https://doi.org/10.1515/jbcpp-2018-0191

Article  PubMed 

留言 (0)

沒有登入
gif