Synovial mesenchymal stem cell-derived exosomal microRNA-320c facilitates cartilage damage repair by targeting ADAM19-dependent Wnt signalling in osteoarthritis rats

Abu Owida H (2022) Recent biomimetic approaches for articular cartilage tissue engineering and their clinical applications: narrative review of the literature. Adv Orthop 2022:8670174

Article  PubMed  PubMed Central  Google Scholar 

Arden NK, Perry TA, Bannuru RR, Bruyere O, Cooper C, Haugen IK, Hochberg MC, McAlindon TE, Mobasheri A, Reginster JY (2021) Non-surgical management of knee osteoarthritis: comparison of ESCEO and OARSI 2019 guidelines. Nat Rev Rheumatol 17:59–66

Article  CAS  PubMed  Google Scholar 

Bai R, Miao MZ, Li H, Wang Y, Hou R, He K, Wu X, Jin H, Zeng C, Cui Y, Lei G (2022) Increased Wnt/beta-catenin signaling contributes to autophagy inhibition resulting from a dietary magnesium deficiency in injury-induced osteoarthritis. Arthritis Res Ther 24:165

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bortoluzzi A, Furini F, Scire CA (2018) Osteoarthritis and its management—epidemiology, nutritional aspects and environmental factors. Autoimmun Rev 17:1097–1104

Article  CAS  PubMed  Google Scholar 

Chen Z, Wang H, Xia Y, Yan F, Lu Y (2018) Therapeutic potential of mesenchymal cell-derived miRNA-150-5p-expressing exosomes in rheumatoid arthritis mediated by the modulation of MMP14 and VEGF. J Immunol 201:2472–2482

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen XY, Wan SF, Yao NN, Lin ZJ, Mao YG, Yu XH, Wang YZ (2021) Inhibition of the immunoproteasome LMP2 ameliorates ischemia/hypoxia-induced blood-brain barrier injury through the Wnt/beta-catenin signalling pathway. Mil Med Res 8:62

CAS  PubMed  PubMed Central  Google Scholar 

De Palma A, Nalesso G (2021) WNT signalling in osteoarthritis and its pharmacological targeting. Handb Exp Pharmacol 269:337–356

Article  PubMed  Google Scholar 

Dennison EM (2022) Osteoarthritis: the importance of hormonal status in midlife women. Maturitas 165:8–11

Article  PubMed  Google Scholar 

Fujii Y, Liu L, Yagasaki L, Inotsume M, Chiba T, Asahara H (2022) Cartilage homeostasis and osteoarthritis. Int J Mol Sci 23:6316

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hu S, Mao G, Zhang Z, Wu P, Wen X, Liao W, Zhang Z (2019) MicroRNA-320c inhibits development of osteoarthritis through downregulation of canonical Wnt signaling pathway. Life Sci 228:242–250

Article  CAS  PubMed  Google Scholar 

Katz JN, Arant KR, Loeser RF (2021) Diagnosis and treatment of hip and knee osteoarthritis: a review. JAMA 325:568–578

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kong R, Gao J, Zhang J, Ji L, Yu Y, Zhang L, Zhao D (2022) Synovial mesenchymal stem cell-derived exosomal miR-320c enhances chondrogenesis by targeting ADAM19. Fut Med Chem 14:81–96

Article  CAS  Google Scholar 

Latourte A, Kloppenburg M, Richette P (2020) Emerging pharmaceutical therapies for osteoarthritis. Nat Rev Rheumatol 16:673–688

Article  PubMed  Google Scholar 

Li TE, Wang S, Shen XT, Zhang Z, Chen M, Wang H, Zhu Y, Xu D, Hu BY, Wei R, Zheng Y, Dong QZ, Qin LX (2020) PKM2 drives hepatocellular carcinoma progression by inducing immunosuppressive microenvironment. Front Immunol 11:589997

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nedunchezhiyan U, Varughese I, Sun AR, Wu X, Crawford R, Prasadam I (2022) Obesity, inflammation, and immune system in osteoarthritis. Front Immunol 13:907750

Article  CAS  PubMed  PubMed Central  Google Scholar 

Peng Z, Sun H, Bunpetch V, Koh Y, Wen Y, Wu D, Ouyang H (2021) The regulation of cartilage extracellular matrix homeostasis in joint cartilage degeneration and regeneration. Biomaterials 268:120555

Article  CAS  PubMed  Google Scholar 

Pritzker KP, Gay S, Jimenez SA, Ostergaard K, Pelletier JP, Revell PA, Salter D, van den Berg WB (2006) Osteoarthritis cartilage histopathology: grading and staging. Osteoarthr Cartil 14:13–29

Article  CAS  Google Scholar 

Qiu M, Liu D, Fu Q (2021) MiR-129-5p shuttled by human synovial mesenchymal stem cell-derived exosomes relieves IL-1beta induced osteoarthritis via targeting HMGB1. Life Sci 269:118987

Article  CAS  PubMed  Google Scholar 

Quicke JG, Conaghan PG, Corp N, Peat G (2022) Osteoarthritis year in review 2021: epidemiology & therapy. Osteoarthr Cartil 30:196–206

Article  CAS  Google Scholar 

Rahmati M, Nalesso G, Mobasheri A, Mozafari M (2017) Aging and osteoarthritis: central role of the extracellular matrix. Ageing Res Rev 40:20–30

Article  CAS  PubMed  Google Scholar 

Sanchez-Lopez E, Coras R, Torres A, Lane NE, Guma M (2022) Synovial inflammation in osteoarthritis progression. Nat Rev Rheumatol 18:258–275

Article  PubMed  PubMed Central  Google Scholar 

Sharma L (2021) Osteoarthritis of the Knee. N Engl J Med 384:51–59

Article  CAS  PubMed  Google Scholar 

Tao SC, Yuan T, Zhang YL, Yin WJ, Guo SC, Zhang CQ (2017) Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model. Theranostics 7:180–195

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tat SK, Pelletier JP, Mineau F, Caron J, Martel-Pelletier J (2011) Strontium ranelate inhibits key factors affecting bone remodeling in human osteoarthritic subchondral bone osteoblasts. Bone 49:559–567

Article  CAS  PubMed  Google Scholar 

Varela-Eirin M, Loureiro J, Fonseca E, Corrochano S, Caeiro JR, Collado M, Mayan MD (2018) Cartilage regeneration and ageing: targeting cellular plasticity in osteoarthritis. Ageing Res Rev 42:56–71

Article  CAS  PubMed  Google Scholar 

Walczak BE, Jiao H, Lee MS, Li WJ (2021) Reprogrammed synovial fluid-derived mesenchymal stem/stromal cells acquire enhanced therapeutic potential for articular cartilage repair. Cartilage 13:530S-543S

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xu X, Liang Y, Li X, Ouyang K, Wang M, Cao T, Li W, Liu J, Xiong J, Li B, Xia J, Wang D, Duan L (2021) Exosome-mediated delivery of kartogenin for chondrogenesis of synovial fluid-derived mesenchymal stem cells and cartilage regeneration. Biomaterials 269:120539

Article  CAS  PubMed  Google Scholar 

Zhang J, Zhang Y, Ma Y, Luo L, Chu M, Zhang Z (2021) Therapeutic potential of exosomal circRNA derived from synovial mesenchymal cells via targeting circEDIL3/miR-485-3p/PIAS3/STAT3/VEGF functional module in rheumatoid arthritis. Int J Nanomed 16:7977–7994

Article  CAS  Google Scholar 

Zheng T, Li Y, Zhang X, Xu J, Luo M (2022) Exosomes derived from miR-212-5p overexpressed human synovial mesenchymal stem cells suppress chondrocyte degeneration and inflammation by targeting ELF3. Front Bioeng Biotechnol 10:816209

Article  PubMed  PubMed Central  Google Scholar 

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