Effects of the theory of planned behavior and nudge strategy-based intervention on the adherence to anticoagulation treatment in patients with non-valvular atrial fibrillation

Background

Non-valvular atrial fibrillation is associated with the incidence of thromboembolism. Current guidelines recommend preferential use of novel oral anticoagulants(NOAC) in patients with nonvalvular atrial fibrillation. Oral anticoagulation medication adherence rate was relatively low among discharged patients with non-valvular atrial fibrillation.

Aim

To investigate the effects of the anticoagulation programs based on the theory of planned behavior and nudge strategy among patients with non-valvular atrial fibrillation.

Methods

130 patients with non-valvular atrial fibrillation were randomized to the intervention group or control group, 72 patients in the intervention group, and 58 patients in the control group with a 6-month follow-up. Medication adherence,intention,attitude, perceived behavioral control and subjective norm and quality of life were assessed.

Results

There were significantly differences in the attitude and subjective norm between the two groups at one month,three months and six months follow-up(P <0.01).There were significantly differences in the perceived behavioral control between the two groups at six months follow-up(P <0.01).There were significantly differences in the intention scale between the two groups at three months follow-up(P <0.01). The medication adherence scale score was higher in the intervention group than in the control group at six months follow-up.However, there were no differences in quality of life between the two groups at six months follow-up.

Conclusions

The program based on the theory of planned behavior and nudge strategy can improve medication adherence in patients with non-valvular atrial fibrillation.

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