Relationship Between Weight-adjusted Waist Index and Osteoporosis in the senile in the United States from the National Health and Nutrition Examination Survey, 2017-2020

Osteoporosis (OP), a serious public health problem worldwide, had a high prevalence of about 18.3% in the general population (1). It was particularly detrimental to the senile, which was the leading cause of secondary fragility fractures in patients (2).

As a traditional parameter to evaluate obesity, body mass index (BMI) had been confirmed to be closely related to OP in many studies in recent years (3, 4, 5, 6), which led researchers to speculate that obesity might be a protective factor for OP. Even though, we would still like to highlight that muscle mass and fat mass cannot be distinguished by the BMI (7,8).

Therefore, we hoped to find a better indicator for obesity that can disgusting whether fat or high muscle mass is associated with a decrease in OP. Weight-adjusted waist index (WWI) was a novel indicator that could combine the two opposite directions of fat and muscle mass in one which was better than BMI for OP study in the senile (9,10). This study aimed to explore the association between WWI and OP in old-aged adults in the United States.

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