Masone MC, Morra V, Venditti R (2019) Illuminating the membrane contact sites between the endoplasmic reticulum and the trans-Golgi network. FEBS Lett 593:3135–3148. https://doi.org/10.1002/1873-3468.13639
Article CAS PubMed Google Scholar
Prinz WA, Toulmay A, Balla T (2020) The functional universe of membrane contact sites. Nat Rev Mol Cell Biol 21:7–24. https://doi.org/10.1038/s41580-019-0180-9
Article CAS PubMed Google Scholar
Siehler J, Blochinger AK, Meier M, Lickert H (2021) Engineering islets from stem cells for advanced therapies of diabetes. Nat Rev Drug Discov 20:920–940. https://doi.org/10.1038/s41573-021-00262-w
Article CAS PubMed Google Scholar
Vance JE (2015) Phospholipid synthesis and transport in mammalian cells. Traffic 16:1–18. https://doi.org/10.1111/tra.12230
Article CAS PubMed Google Scholar
Stefan CJ, Trimble WS, Grinstein S, Drin G, Reinisch K, De Camilli P, Cohen S, Valm AM, Lippincott-Schwartz J, Levine TP et al (2017) Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers. BMC Biol 15:102. https://doi.org/10.1186/s12915-017-0432-0
Article CAS PubMed PubMed Central Google Scholar
Lev S (2012) Nonvesicular lipid transfer from the endoplasmic reticulum. Cold Spring Harb Perspect Biol 4:a013300. https://doi.org/10.1101/cshperspect.a013300
Article CAS PubMed PubMed Central Google Scholar
Reinisch KM, Prinz WA (2021) Mechanisms of nonvesicular lipid transport. J Cell Biol 220:e202012058. https://doi.org/10.1083/jcb.202012058
Article CAS PubMed PubMed Central Google Scholar
Wong LH, Gatta AT, Levine TP (2019) Lipid transfer proteins: the lipid commute via shuttles, bridges and tubes. Nat Rev Mol Cell Biol 20:85–101. https://doi.org/10.1038/s41580-018-0071-5
Article CAS PubMed Google Scholar
Lipp NF, Ikhlef S, Milanini J, Drin G (2020) Lipid exchangers: cellular functions and mechanistic links with phosphoinositide metabolism. Front Cell Dev Biol 8:663. https://doi.org/10.3389/fcell.2020.00663
Article PubMed PubMed Central Google Scholar
Chiapparino A, Maeda K, Turei D, Saez-Rodriguez J, Gavin AC (2016) The orchestra of lipid-transfer proteins at the crossroads between metabolism and signaling. Prog Lipid Res 61:30–39. https://doi.org/10.1016/j.plipres.2015.10.004
Article CAS PubMed Google Scholar
Kentala H, Weber-Boyvat M, Olkkonen VM (2016) OSBP-related protein family: mediators of lipid transport and signaling at membrane contact sites. Int Rev Cell Mol Biol 321:299–340. https://doi.org/10.1016/bs.ircmb.2015.09.006
Article CAS PubMed Google Scholar
Raychaudhuri S, Prinz WA (2010) The diverse functions of oxysterol-binding proteins. Annu Rev Cell Dev Biol 26:157–177. https://doi.org/10.1146/annurev.cellbio.042308.113334
Article CAS PubMed PubMed Central Google Scholar
Olkkonen VM (2013) OSBP-related proteins: liganding by glycerophospholipids opens new insight into their function. Molecules 18:13666–13679. https://doi.org/10.3390/molecules181113666
Article CAS PubMed PubMed Central Google Scholar
Weber-Boyvat M, Kentala H, Peranen J, Olkkonen VM (2015) Ligand-dependent localization and function of ORP-VAP complexes at membrane contact sites. Cell Mol Life Sci 72:1967–1987. https://doi.org/10.1007/s00018-014-1786-x
Article CAS PubMed Google Scholar
Kaiser SE, Brickner JH, Reilein AR, Fenn TD, Walter P, Brunger AT (2005) Structural basis of FFAT motif-mediated ER targeting. Structure 13:1035–1045. https://doi.org/10.1016/j.str.2005.04.010
Article CAS PubMed Google Scholar
Murphy SE, Levine TP (2016) VAP, a versatile access point for the endoplasmic reticulum: review and analysis of FFAT-like motifs in the VAPome. Biochim Biophys Acta 1861:952–961. https://doi.org/10.1016/j.bbalip.2016.02.009
Article CAS PubMed Google Scholar
Lemmon MA (2007) Pleckstrin homology (PH) domains and phosphoinositides. Biochem Soc Symp 1:81–93. https://doi.org/10.1042/BSS0740081
Galmes R, Houcine A, Vliet AR, Agostinis P, Jackson CL, Giordano F (2016) ORP5/ORP8 localize to endoplasmic reticulum–mitochondria contacts and are involved in mitochondrial function. EMBO Rep 17:800–810. https://doi.org/10.15252/embr.201541108
Article CAS PubMed PubMed Central Google Scholar
Ghai R, Du X, Wang H, Dong J, Ferguson C, Brown AJ, Parton RG, Wu JW, Yang H (2017) ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane. Nat Commun 8:757. https://doi.org/10.1038/s41467-017-00861-5
Article CAS PubMed PubMed Central Google Scholar
Mesmin B, Bigay J, Moser von Filseck J, Lacas-Gervais S, Drin G, Antonny B (2013) A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBP. Cell 155:830–843. https://doi.org/10.1016/j.cell.2013.09.056
Article CAS PubMed Google Scholar
Levine TP, Munro S (2002) Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components. Curr Biol CB 12:695–704. https://doi.org/10.1016/s0960-9822(02)00779-0
Article CAS PubMed Google Scholar
Peretti D, Dahan N, Shimoni E, Hirschberg K, Lev S (2008) Coordinated lipid transfer between the endoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport. Mol Biol Cell 19:3871–3884. https://doi.org/10.1091/mbc.e08-05-0498
Article CAS PubMed PubMed Central Google Scholar
de la Mora E, Dezi M, Di Cicco A, Bigay J, Gautier R, Manzi J, Polidori J, Castano-Diez D, Mesmin B, Antonny B et al (2021) Nanoscale architecture of a VAP-A-OSBP tethering complex at membrane contact sites. Nat Commun 12:3459. https://doi.org/10.1038/s41467-021-23799-1
Article CAS PubMed PubMed Central Google Scholar
Jamecna D, Polidori J, Mesmin B, Dezi M, Levy D, Bigay J, Antonny B (2019) An intrinsically disordered region in OSBP acts as an entropic barrier to control protein dynamics and orientation at membrane contact sites. Dev Cell 49:220–234. https://doi.org/10.1016/j.devcel.2019.02.021
Article CAS PubMed Google Scholar
Lim CY, Davis OB, Shin HR, Zhang J, Berdan CA, Jiang X, Counihan JL, Ory DS, Nomura DK, Zoncu R (2019) ER-lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann-Pick type C. Nat Cell Biol 21:1206–1218. https://doi.org/10.1038/s41556-019-0391-5
Article CAS PubMed PubMed Central Google Scholar
Tan JX, Finkel T (2022) A phosphoinositide signalling pathway mediates rapid lysosomal repair. Nature 609:815–821. https://doi.org/10.1038/s41586-022-05164-4
Article CAS PubMed PubMed Central Google Scholar
Balla T (2013) Phosphoinositides: tiny lipids with giant impact on cell regulation. Physiol Rev 93:1019–1137. https://doi.org/10.1152/physrev.00028.2012
Article CAS PubMed PubMed Central Google Scholar
Hammond GRV, Burke JE (2020) Novel roles of phosphoinositides in signaling, lipid transport, and disease. Curr Opin Cell Biol 63:57–67. https://doi.org/10.1016/j.ceb.2019.12.007
Article CAS PubMed PubMed Central Google Scholar
Santiago-Tirado FH, Bretscher A (2011) Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans-Golgi network. Trends Cell Biol 21:515–525. https://doi.org/10.1016/j.tcb.2011.05.005
Article CAS PubMed PubMed Central Google Scholar
De Matteis MA, Wilson C, D’Angelo G (2013) Phosphatidylinositol-4-phosphate: the Golgi and beyond. BioEssays 35:612–622. https://doi.org/10.1002/bies.201200180
Article CAS PubMed Google Scholar
Tan J, Brill JA (2014) Cinderella story: PI4P goes from precursor to key signaling molecule. Crit Rev Biochem Mol Biol 49:33–58. https://doi.org/10.3109/10409238.2013.853024
Article CAS PubMed Google Scholar
Waugh MG (2019) The Great Escape: how phosphatidylinositol 4-kinases and PI4P promote vesicle exit from the Golgi (and drive cancer). Biochem J 476:2321–2346. https://doi.org/10.1042/BCJ20180622
Article CAS PubMed Google Scholar
Venditti R, Masone MC, Rega LR, Di Tullio G, Santoro M, Polishchuk E, Serrano IC, Olkkonen VM, Harada A, Medina DL et al (2019) The activity of Sac1 across ER-TGN contact sites requires the four-phosphate-adaptor-protein-1. J Cell Biol 218:783–797. https://doi.org/10.1083/jcb.201812021
Article CAS PubMed PubMed Central Google Scholar
Mesmin B, Bigay J, Polidori J, Jamecna D, Lacas-Gervais S, Antonny B (20
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