COVID-19 Vaccination and Thyroiditis

After the emergence of a new coronavirus variant in China, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19), several vaccines have been rapidly developed in an attempt to immunize and protect populations [1], [2]. After massive vaccination campaigns using diverse types of vaccines against SARS-CoV-2, several autoimmune-inflammatory disorders have been reported and linked with vaccines [3]. This review focused on SARS-CoV-2 vaccine-induced autoimmune and inflammatory thyroid disorders and summarized the current understanding. Furthermore, we addressed the challenges in the clinical management of vaccine-induced thyroid diseases and discussed possible pathophysiological mechanisms. Finally, we determined the knowledge gap and proposed a research agenda.

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