In vitro differentiation of myeloid suppressor cells (MDSC-like) from an immature myelomonocytic precursor THP-1

AML

Acute Myeloid Leukemia

BD

Becton, Dickinson and Company

CCL18

C-C motif chemokine ligand 18

CCL22

C-C motif chemokine ligand 22

CD122 (IL2RB)

interleukin 2 receptor subunit beta

CD

Cluster of differentiation

CD206 (MRC1)

mannose receptor C-type 1

CXCL10

C-X-C motif chemokine ligand 10 also known as interferon-gamma inducible protein (IP-10)

F

forward primer (left primer)

FITC

Fluorescein isothiocyanate

GAPDH

glyceraldehyde-3-phosphate dehydrogenase

G-CSF

Granulocyte colony-stimulating factor

GM-CSF

granulocyte-macrophage colony-stimulating factor

IDO

Indoleamine 2,3-dioxygenase

LAG-3

lymphocyte-activation gene 3

Lin1

Anti-Human Lineage Cocktail 1

MDSC

Myeloid-Derived Suppressor Cell

MFI

mean fluorescence intensity

NOS2

Nitric oxide synthase 2

PBMC

Peripheral blood mononuclear cells

PBS

Phosphate buffered saline

PC5

R-phycoerythrin-Cyanine 5

PCR

polymerase chain reaction

PD-1

Programmed cell death protein 1

PD-L1 (CD274)

Programmed death-ligand 1

PMA

phorbol 12-myristate 13-acetate

R

reverse primer (right primer)

SA-PE

streptavidin-conjugated with phycoerythrin

S100A8

S100 Calcium Binding Protein A8

S100A9

S100 Calcium Binding Protein A9

TAM

tumor-associated macrophages

TGF-β

Transforming growth factor beta

TMF

tumor microenvironment

留言 (0)

沒有登入
gif