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Making an important scientific discovery is just the first step in a process. One also needs to communicate that scientific discovery and its impact, and get it accepted into the mainstream of research in order to advance a field. Communicating discoveries is where scientific journals play a critical role through their implementation of the peer review process and dissemination of the findings. This process is imperfect for a variety of reasons. Most commonly, journal editors and reviewers that assess manuscripts for publication can fail to appreciate findings, especially when they go against the current accepted views of a given field. While you might expect scientists, including editors and reviewers, to be open-minded about new discoveries that alter the trajectory of a field, all to commonly they are not. Many are risk-adverse or lack sufficient depth of knowledge to assess paradigm shifts. Throughout my career, I and my collaborators and colleagues have encountered this obstacle in publishing. This is where an exceptional journal editor, Terri Grodzicker, at the helm of Genes & Development for 35 years, made remarkable and lasting contributions to science. Her ability to recognize paradigm-shifting work, identify exceptional reviewers of the same ilk, and make the appropriate interpretations of the manuscript reviews drove impactful science forward. I am greatly indebted to Terri for the intellectual capacity, vision, and boldness to recognize these major paradigm shifts, first in the field of apoptosis and later in autophagy. G&D published many but not all of our papers that are now accepted mainstays with thousands of citations and clinical impact for cancer treatment.
In the late 1980s to early 1990s, a transformation in our understanding of cell death occurred. Prior to this time, if your cells died you threw your experiment in the garbage. Apoptosis was described morphologically; however, there was a …
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