A major mechanism for immunomodulation: Dietary fibres and acid metabolites

AbbreviationsSCFAs

Short-chain fatty acids

DP

Degree of polymerization

IBD

Inflammatory bowel disease

DSS

Dextran sulfate sodium

CVDs

Cardiovascular diseases

HMOs

Human milk oligosaccharides

CAZymes

Carbohydrate-active enzymes

HDACs

Histone deacetylases

GPCRs

G-protein coupled receptors

HIF-1α

Hypoxia-induced factor 1α

TH17

Type 17 helper T cells

HAMS

High amylose maze starch

HAMSA

HAMS conjugated with acetate

HAMSB

HAMS conjugated with butyrate

HAMSP

HAMS conjugated with propionate

Keywords

Short-chain fatty acids (SCFA)

GPR43

GPR65

Proton sensing

Dietary fibre

Gut microbiota/microbiome

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