Levental, I., Georges, P. C. & Janmey, P. A. Soft biological materials and their impact on cell function. Soft Matter 3, 299–306 (2007).
Article CAS PubMed Google Scholar
Swift, J. et al. Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science 341, 1240104 (2013).
Article PubMed PubMed Central Google Scholar
Storm, C., Pastore, J. J., MacKintosh, F. C., Lubensky, T. C. & Janmey, P. A. Nonlinear elasticity in biological gels. Nature 435, 191–194 (2005).
Article CAS PubMed Google Scholar
Discher Dennis, E., Janmey, P. & Wang, Y.-L. Tissue cells feel and respond to the stiffness of their substrate. Science 310, 1139–1143 (2005).
Article CAS PubMed Google Scholar
Vogel, V. & Sheetz, M. Local force and geometry sensing regulate cell functions. Nat. Rev. Mol. Cell Biol. 7, 265–275 (2006).
Article CAS PubMed Google Scholar
Wozniak, M. A. & Chen, C. S. Mechanotransduction in development: a growing role for contractility. Nat. Rev. Mol. Cell Biol. 10, 34–43 (2009).
Article CAS PubMed PubMed Central Google Scholar
DuFort, C. C., Paszek, M. J. & Weaver, V. M. Balancing forces: architectural control of mechanotransduction. Nat. Rev. Mol. Cell Biol. 12, 308–319 (2011).
Article CAS PubMed PubMed Central Google Scholar
Kechagia, J. Z., Ivaska, J. & Roca-Cusachs, P. Integrins as biomechanical sensors of the microenvironment. Nat. Rev. Mol. Cell Biol. 20, 457–473 (2019).
Article CAS PubMed Google Scholar
Cukierman, E., Pankov, R., Stevens, D. R. & Yamada, K. M. Taking cell-matrix adhesions to the third dimension. Science 294, 1708–1712 (2001). This articles demonstrates the key differences in the structure and composition of cell–ECM adhesions for fibroblasts between 2D culture, 3D culture and tissues.
Article CAS PubMed Google Scholar
Baker, B. M. & Chen, C. S. Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues. J. Cell Sci. 125, 3015–3024 (2012).
CAS PubMed PubMed Central Google Scholar
Von Der Mark, K., Gauss, V., Von Der Mark, H. & MÜLler, P. Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture. Nature 267, 531–532 (1977).
Petersen, O. W., Rønnov-Jessen, L., Howlett, A. R. & Bissell, M. J. Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc. Natl Acad. Sci. USA 89, 9064–9068 (1992).
Article CAS PubMed PubMed Central Google Scholar
Gerecht, S. et al. Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells. Proc. Natl Acad. Sci. USA 104, 11298–11303 (2007).
Article CAS PubMed PubMed Central Google Scholar
Fischbach, C. et al. Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement. Proc. Natl Acad. Sci. USA 106, 399–404 (2009).
Article CAS PubMed PubMed Central Google Scholar
Fratzl, P. in Collagen: Structure and Mechanics (ed. Fratzl, P.) 1–13 (Springer, 2008).
Jokinen, J. et al. Integrin-mediated cell adhesion to type I collagen fibrils. J. Biol. Chem. 279, 31956–31963 (2004).
Article CAS PubMed Google Scholar
Humphries, J. D., Byron, A. & Humphries, M. J. Integrin ligands at a glance. J. Cell Sci. 119, 3901–3903 (2006).
Article CAS PubMed Google Scholar
Gautieri, A., Vesentini, S., Redaelli, A. & Buehler, M. J. Hierarchical structure and nanomechanics of collagen microfibrils from the atomistic scale up. Nano Lett. 11, 757–766 (2011).
Article CAS PubMed Google Scholar
Vader, D., Kabla, A., Weitz, D. & Mahadevan, L. Strain-induced alignment in collagen gels. PLoS ONE 4, e5902 (2009).
Article PubMed PubMed Central Google Scholar
Proestaki, M., Ogren, A., Burkel, B. & Notbohm, J. Modulus of fibrous collagen at the length scale of a cell. Exp. Mech. 59, 1323–1334 (2019).
Article CAS PubMed PubMed Central Google Scholar
Hotary, K., Allen, E., Punturieri, A., Yana, I. & Weiss, S. J. Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. J. Cell Biol. 149, 1309–1323 (2000).
Article CAS PubMed PubMed Central Google Scholar
Münster, S. et al. Strain history dependence of the nonlinear stress response of fibrin and collagen networks. Proc. Natl Acad. Sci. USA 110, 12197–12202 (2013).
Article PubMed PubMed Central Google Scholar
Nam, S., Hu, K. H., Butte, M. J. & Chaudhuri, O. Strain-enhanced stress relaxation impacts nonlinear elasticity in collagen gels. Proc. Natl Acad. Sci. USA 113, 5492–5497 (2016).
Article CAS PubMed PubMed Central Google Scholar
Ban, E. et al. Mechanisms of plastic deformation in collagen networks induced by cellular forces. Biophys. J. 114, 450–461 (2018).
Article CAS PubMed PubMed Central Google Scholar
Collet, J.-P., Shuman, H., Ledger, R. E., Lee, S. & Weisel, J. W. The elasticity of an individual fibrin fiber in a clot. Proc. Natl Acad. Sci. USA 102, 9133–9137 (2005).
Article CAS PubMed PubMed Central Google Scholar
Brown, A. E. X., Litvinov, R. I., Discher, D. E., Purohit, P. K. & Weisel, J. W. Multiscale mechanics of fibrin polymer: gel stretching with protein unfolding and loss of water. Science 325, 741–744 (2009).
Article CAS PubMed PubMed Central Google Scholar
Yurchenco, P. D. Basement membranes: cell scaffoldings and signaling platforms. Cold Spring Harb. Perspect. Biol. 3, a004911 (2011).
Article PubMed PubMed Central Google Scholar
Chang, J. & Chaudhuri, O. Beyond proteases: basement membrane mechanics and cancer invasion. J. Cell Biol. 218, 2456–2469 (2019).
Article PubMed PubMed Central Google Scholar
Li, H., Zheng, Y., Han, Y. L., Cai, S. & Guo, M. Nonlinear elasticity of biological basement membrane revealed by rapid inflation and deflation. Proc. Natl Acad. Sci. USA 118, e2022422118 (2021).
Article CAS PubMed PubMed Central Google Scholar
Stowers, R. S. et al. Extracellular matrix stiffening induces a malignant phenotypic transition in breast epithelial cells. Cell. Mol. Bioeng. 10, 114–123 (2017).
Article CAS PubMed Google Scholar
Reuten, R. et al. Basement membrane stiffness determines metastases formation. Nat. Mater. 20, 892–903 (2021).
Article CAS PubMed Google Scholar
Kleinman, H. K. & Martin, G. R. Matrigel: Basement membrane matrix with biological activity. Semin. Cancer Biol. 15, 378–386 (2005).
Article CAS PubMed Google Scholar
Chopra, A. et al. Augmentation of integrin-mediated mechanotransduction by hyaluronic acid. Biomaterials 35, 71–82 (2014).
Article CAS PubMed Google Scholar
Wolf, K. J. et al. A mode of cell adhesion and migration facilitated by CD44-dependent microtentacles. Proc. Natl Acad. Sci. USA 117, 11432–11443 (2020).
Article CAS PubMed PubMed Central Google Scholar
Wolf, K. J. & Kumar, S. Hyaluronic acid: incorporating the bio into the material. ACS Biomater. Sci. Eng. 5, 3753–3765 (2019).
Article CAS PubMed PubMed Central Google Scholar
Burdick, J. A. & Prestwich, G. D. Hyaluronic acid hydrogels for biomedical applications. Adv. Mater. 23, H41–H56 (2011).
Article CAS PubMed PubMed Central Google Scholar
Vogel, V. Mechanotransduction involving multimodular proteins: converting force into biochemical signals. Annu. Rev. Biophys. Biomol. Struct. 35, 459–488 (2006).
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