Berger A, Witt A, Haiden N, Kaider A, Klebermasz K, Fuiko R et al (2009) Intrauterine infection with Ureaplasma species is associated with adverse neuromotor outcome at 1 and 2 years adjusted age in preterm infants. J Perinat Med 37(1):72–78
Cohen GM (1997) Caspases: the executioners of apoptosis. Biochem J 326(Pt 1):1–16
Article CAS PubMed PubMed Central Google Scholar
Cruz-Orengo L, Holman DW, Dorsey D, Zhou L, Zhang P, Wright M et al (2011) CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity. J Exp Med 208(2):327–339
Article CAS PubMed PubMed Central Google Scholar
Forrester JV, McMenamin PG, Dando SJ (2018) CNS infection and immune privilege. Nat Rev Neurosci 19(11):655–671
Article CAS PubMed Google Scholar
Glaser K, Speer CP (2015) Neonatal CNS infection and inflammation caused by Ureaplasma species: rare or relevant? Expert Rev Anti Infect Ther. 13(2):233–48
Article CAS PubMed Google Scholar
Glaser K, Wohlleben M, Speer CP (2015) An 8-month history of meningitis in an extremely low birth weight infant?—long-lasting Infection with Ureaplasma parvum. Z Geburtshilfe Neonatol 219(1):52–56
Glaser K, Silwedel C, Fehrholz M, Waaga-Gasser AM, Henrich B, Claus H et al (2017) Ureaplasma species differentially modulate pro- and anti-inflammatory cytokine responses in newborn and adult human monocytes pushing the state toward pro-inflammation. Front Cell Infect Microbiol. 7:484
Article PubMed PubMed Central Google Scholar
Glaser K, Silwedel C, Fehrholz M, Henrich B, Waaga-Gasser AM, Claus H et al (2018a) Ureaplasma isolates stimulate pro-inflammatory CC chemokines and matrix metalloproteinase-9 in neonatal and adult monocytes. PLoS One. 13(3):e0194514
Article PubMed PubMed Central Google Scholar
Glaser K, Silwedel C, Waaga-Gasser AM, Henrich B, Fehrholz M, Claus H et al (2018b) Ureaplasma isolates differentially modulate growth factors and cell adhesion molecules in human neonatal and adult monocytes. Cytokine 105:45–8
Article CAS PubMed Google Scholar
Glaser K, Gradzka-Luczewska A, Szymankiewicz-Breborowicz M, Kawczynska-Leda N, Henrich B, Waaga-Gasser AM et al (2019) Perinatal Ureaplasma exposure is associated with increased risk of late onset sepsis and imbalanced inflammation in preterm infants and may add to lung injury. Front Cell Infect Microbiol. https://doi.org/10.3389/fcimb.2019
Article PubMed PubMed Central Google Scholar
Goldenberg RL, Hauth JC, Andrews WW (2000) Intrauterine infection and preterm delivery. N Engl J Med 342(20):1500–1507
Article CAS PubMed Google Scholar
Goldenberg RL, Andrews WW, Goepfert AR, Faye-Petersen O, Cliver SP, Carlo WA et al (2008) The Alabama Preterm Birth Study: umbilical cord blood Ureaplasma urealyticum and Mycoplasma hominis cultures in very preterm newborn infants. Am J Obstet Gynecol. 198(1):43e1-5
Groneck P, Schmale J, Soditt V, Stutzer H, Gotze-Speer B, Speer CP (2001) Bronchoalveolar inflammation following airway infection in preterm infants with chronic lung disease. Pediatr Pulmonol 31(5):331–338
Article CAS PubMed Google Scholar
Gussenhoven R, Ophelders D, Kemp MW, Payne MS, Spiller OB, Beeton ML et al (2017) The paradoxical effects of chronic intra-amniotic Ureaplasma parvum exposure on ovine fetal brain development. Dev Neurosci 39(6):472–486
Article CAS PubMed Google Scholar
Hamilton JA (2008) Colony-stimulating factors in inflammation and autoimmunity. Nat Rev Immunol 8(7):533–544
Article CAS PubMed Google Scholar
Huang J, Li Y, Tang Y, Tang G, Yang GY, Wang Y (2013) CXCR4 antagonist AMD3100 protects blood-brain barrier integrity and reduces inflammatory response after focal ischemia in mice. Stroke 44(1):190–197
Article CAS PubMed Google Scholar
Ireland DJ, Keelan JA (2014) The maternal serological response to intrauterine Ureaplasma sp. infection and prediction of risk of pre-term birth. Front Immunol 5:624
Article PubMed PubMed Central Google Scholar
Jorgensen I, Rayamajhi M, Miao EA (2017) Programmed cell death as a defence against infection. Nat Rev Immunol 17(3):151–164
Article CAS PubMed PubMed Central Google Scholar
Kasper DC, Mechtler TP, Reischer GH, Witt A, Langgartner M, Pollak A et al (2010) The bacterial load of Ureaplasma parvum in amniotic fluid is correlated with an increased intrauterine inflammatory response. Diagn Microbiol Infect Dis 67(2):117–121
Kasper DC, Mechtler TP, Bohm J, Petricevic L, Gleiss A, Spergser J et al (2011) In utero exposure to Ureaplasma spp. is associated with increased rate of bronchopulmonary dysplasia and intraventricular hemorrhage in preterm infants. J Perinat Med. 39(3):331–6
Kelleher MA, Liu Z, Wang X, Kroenke CD, Houser LA, Dozier BL et al (2017) Beyond the uterine environment: a nonhuman primate model to investigate maternal-fetal and neonatal outcomes following chronic intrauterine infection. Pediatr Res 82(2):244–252
Article PubMed PubMed Central Google Scholar
Le Thuc O, Blondeau N, Nahon JL, Rovere C (2015) The complex contribution of chemokines to neuroinflammation: switching from beneficial to detrimental effects. Ann N Y Acad Sci 1351:127–140
Liu KK, Dorovini-Zis K (2009) Regulation of CXCL12 and CXCR4 expression by human brain endothelial cells and their role in CD4+ and CD8+ T cell adhesion and transendothelial migration. J Neuroimmunol 215(1–2):49–64
Article CAS PubMed Google Scholar
Liu L, Johnson HL, Cousens S, Perin J, Scott S, Lawn JE et al (2012) Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet 379(9832):2151–2161
Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25(4):402–408
Article CAS PubMed Google Scholar
Man SM, Kanneganti TD (2016) Converging roles of caspases in inflammasome activation, cell death and innate immunity. Nat Rev Immunol 16(1):7–21
Article CAS PubMed Google Scholar
Mobius N, Brenneisen W, Schaeffer A, Henrich B (2012) Protocol for the rapid detection of the urogenital tract mollicutes and Chlamydia with concomitant LGV-(sub)typing. Methods Mol Biol 903:235–253
Moll NM, Cossoy MB, Fisher E, Staugaitis SM, Tucky BH, Rietsch AM et al (2009) Imaging correlates of leukocyte accumulation and CXCR4/CXCL12 in multiple sclerosis. Arch Neurol 66(1):44–53
Article PubMed PubMed Central Google Scholar
Normann E, Lacaze-Masmonteil T, Eaton F, Schwendimann L, Gressens P, Thebaud B (2009) A novel mouse model of Ureaplasma-induced perinatal inflammation: effects on lung and brain injury. Pediatr Res 65(4):430–436
Novy MJ, Duffy L, Axthelm MK, Sadowsky DW, Witkin SS, Gravett MG et al (2009) Ureaplasma parvum or Mycoplasma hominis as sole pathogens cause chorioamnionitis, preterm delivery, and fetal pneumonia in rhesus macaques. Reprod Sci 16(1):56–70
Article CAS PubMed Google Scholar
Ophelders D, Boots AW, Hütten MC, Al-Nasiry S, Jellema RK, Spiller OB et al (2021) Screening of Chorioamnionitis Using Volatile Organic Compound Detection in Exhaled Breath: A Pre-clinical Proof of Concept Study. Front Pediatr. 9:617906
Article PubMed PubMed Central Google Scholar
Ramesh G, MacLean AG, Philipp MT (2013) Cytokines and chemokines at the crossroads of neuroinflammation, neurodegeneration, and neuropathic pain. Mediators Inflamm. https://doi.org/10.1155/2013/480739
Article PubMed PubMed Central Google Scholar
Rittenschober-Böhm J, Habermüller T, Waldhoer T, Fuiko R, Schulz SM, Pimpel B et al (2021) Maternal vaginal Ureaplasma spp. colonization in early pregnancy is associated with adverse short- and long-term outcome of very preterm infants. Children (Basel). https://doi.org/10.3390/children8040276
Rowlands RS, Kragh K, Sahu S, Maddocks SE, Bolhuis A, Spiller OB et al (2021) A requirement for flow to enable the development of Ureaplasma parvum biofilms in vitro. J Appl Microbiol. https://doi.org/10.1111/jam.15120
Senthamaraikannan P, Presicce P, Rueda CM, Maneenil G, Schmidt AF, Miller LA et al (2016) Intra-amniotic Ureaplasma parvum-induced maternal and fetal inflammation and immune responses in rhesus macaques. J Infect Dis 214(10):1597–1604
Article CAS PubMed PubMed Central Google Scholar
Shaalan A, Carpenter G, Proctor G (2018) Caspases are key regulators of inflammatory and innate immune responses mediated by TLR3 in vivo. Mol Immunol 94:190–199
Article CAS PubMed Google Scholar
Silwedel C, Speer CP, Glaser K (2017) Ureaplasma-associated prenatal, perinatal, and neonatal morbidities. Expert Rev Clin Immunol 13(11):1073–1087
留言 (0)