Jinhong Wu, Hao Zhang, Yongsheng Shi, Jinrong Wang, Yuling Han, Qiaoling Zhang, Ning Wang, Sha Liu, Yuehua Zhang, Huifen Zi, Fei Wang, Aihong Liu, Yuxin Song, ChunMei Jia, Yong Feng, Quanhua Liu, liya Wan, Minghong Ji, Zhen Long, Jianfeng Huang, Li Liu, Yun Sun, Suping Tang, Xiaoyan Dong, Xiaojian Zhou, Wenhui Jiang, Li Shen and Haohua Jiang contributed equally to the paper

Department of Respiratory Medicine, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China

Jinhong Wu

Department of Internal Medicine, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China

Hao Zhang

Department of Pediatric Respiratory, Maternity and Child-Care Hospital of Gansu Province, Lanzhou, 730050, China

Yongsheng Shi

Department of Pediatric Respiratory, Affiliated Provincial Hospital of Shandong First Medical University, Jinan, 250021, China

Jinrong Wang

Department of Respiratory, Qilu Children’s Hospital of Shandong University, Jinan, 250022, China

Yuling Han

Department of Pediatric Respiratory, Maternal and Child Health Hospital in Inner Mongolia Autonomous Region, Hohhot, 010020, China

Qiaoling Zhang

Asthma Centre of Xi’an Children’s Hospital, Xi’an, 710003, China

Ning Wang

Department of Respiratory Medicine, Children’s Hospital of Chongqing Medical University, Chongqing, 400014, China

Sha Liu

Pediatrics Infection Disease Ward, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, Haikou, 570208, China

Yuehua Zhang

Department of Pediatrics, Baotou Central Hospital, Baotou, 014040, China

Huifen Zi

Department of Pediatric Respiratory, Guiyang Maternal and Child Health Hospital (Guiyang Children’s Hospital), Guiyang, 550003, China

Fei Wang

Department of Respiratory Medicine, Children’s Hospital of Shanxi, Taiyuan, 030013, China

Aihong Liu

Department of Allergy, Harbin Children’s Hospital, Harbin, 150010, China

Yuxin Song

Department of Pediatric Respiratory, The Fourth Hospital of Baotou (Baotou Children’s Hospital), Baotou, 014030, China

ChunMei Jia

Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, 110004, China

Yong Feng

Department of Pulmonology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China

Quanhua Liu

Respiratory Department, Tianjin Children’s Hospital, Tianjin, 300074, China

liya Wan

Department of Pediatric, The First Affiliated Hospital of USTC Anhui Provincial Hospital, Hefei, 230001, China

Minghong Ji

Department of Pediatric Respiratory Medicine, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430070, China

Zhen Long

Department of Pulmonology, Children’s Hospital of Fudan University, Shanghai, 201102, China

Jianfeng Huang

Department of Pediatric Respiratory, The First Hospital of Jilin University, Changchun, 130021, China

Li Liu

General Pediatric, Yinchuan Women and Children Healthcare Hospital, Yinchuan, 750001, China

Yun Sun

Department of Asthma and Tracheitis, Fuzhou Children’s Hospital, Fujian Medical University, Fuzhou, 350000, China

Suping Tang

Department of Pulmonology, Shanghai Children’s Hospital, Affiliated to Shanghai Jiao Tong University, Shanghai, 200040, China

Xiaoyan Dong

Department of Pediatrics, Shanghai First People’s Hospital, Affiliated to Shanghai Jiao Tong University, Shanghai, 200080, China

Xiaojian Zhou

Department of Respiratory, Guangzhou Women and Children’s Medical Center, Guangzhou, 510623, China

Wenhui Jiang

Department of Respiratory, Shanghai Chest Hospital Affiliated to Shanghai Jiaotong University, Shanghai, 200025, China

Li Shen & Haohua Jiang