Leishangthem S, Sharma LD (2014) Study of some important medicinal plants found in Imphal-East District, Manipur India. Int J Sci Res Publ 4(9):1–5

Google Scholar 

Lakshman CD (2016) Medicinal and aromatic plants of North-East India. Int J Dev Res 6(11):10104–10114

Google Scholar 

Tewari B, Medhabati M (2019) Anti-ulcer effect of aqueous extract of Gynura cusimbua (D. Don) S. Moore on swimming stress ulcer model in albino rats. J Evol Med Dent Sci 8(33):2602–2607. https://doi.org/10.1460/jemds/2019/567

Article  CAS  Google Scholar 

Pradheep K, Pandey A, Bhatt KC (2016) Wild edible plants used by Konyak tribe in Mon district of Nagaland: survey and inventorisation. Indian J Nat Prod Resour 7(1):74–81. https://doi.org/10.56042/ijnpr.v7i1.9963

Article  Google Scholar 

Ma Q, Wei R, Zhou B, Sang Z, Liu W, Cao Z (2019) Antiangiogenic phenylpropanoid glycosides from Gynura cusimbua. Nat Prod Res 33(4):457–463. https://doi.org/10.1080/14786419.2017.1389931

Article  CAS  PubMed  Google Scholar 

Singh TS, Roy SS, Kshetri P, Ansari MA, Sharma SK, Verma MR, Singh IM, Prakash N, Kandpal B (2021) Comparative study on phenolic, flavonoids and in vitro antioxidant activity of wild edible plants from Loktak Lake wetland ecosystem under North East Indian Himalayan Region. Nat Prod Res 35(24):6045–6048. https://doi.org/10.1080/14786419.2020.1817014

Article  CAS  PubMed  Google Scholar 

Ma Q, Wei R, Zhong G, Sang Z (2020) Neuroprotective flavonoids from the aerial parts of Gynura cusimbua. Chem Nat Compd 56(4):725–728. https://doi.org/10.1007/s10600-020-03131-x

Article  CAS  Google Scholar 

Meng X, Li J, Li M, Wang H, Ren B, Chen J, Li W (2021) Traditional uses, phytochemistry, pharmacology and toxicology of the genus Gynura (Compositae): a comprehensive review. J Ethnopharmacol 276:114145. https://doi.org/10.1016/j.jep.2021.114145

Article  CAS  PubMed  Google Scholar 

Rana VS, Blazquez MA (2007) Chemical constituents of Gynura cusimbua aerial parts. J Essent Oil Res 19(1):21–22. https://doi.org/10.1080/10412905.2007.9699219

Article  CAS  Google Scholar 

Cai L, Feng Y (2020) Effects of exogenous ABA on the physiological characteristics and chlorophyll fluorescence of Gynura cusimbua seedlings under drought stress. InIOP Conf Ser: Earth Environ Sci 615(1):012089. https://doi.org/10.1088/1755-1315/615/1/012089

Article  Google Scholar 

Li J, Qin Y, Yu X, Xiong Z, Zheng L, Sun Y, Shen J, Guo N, Tao L, Deng Z, Liu X (2019) In vitro simulated digestion and in vivo metabolism of chlorogenic acid dimer from Gynura procumbens (Lour.) Merr.: enhanced antioxidant activity and different metabolites of blood and urine. J Food Biochem 43:e12654. https://doi.org/10.1111/jfbc.12654

Article  CAS  PubMed  Google Scholar 

Kim HH, Ha SE, Vetrivel P, Bhosale PB, Kim SM, Kim GS (2021) Potential antioxidant and anti-inflammatory function of Gynura procumbens polyphenols ligand. Int J Mol Sci 22:8716. https://doi.org/10.3390/ijms22168716

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang L, Pan X, Jiang L, Chu Y, Gao S, Jiang X, Zhang Y, Chen Y, Luo S, Peng C (2022) The biological activity mechanism of chlorogenic acid and its applications in food industry: a review. Front Nutr 9:943911. https://doi.org/10.3389/fnut.2022.943911

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kristiningrum N, Retnaningtyas Y, Pertiwi NP (2015) Validated TLC-densitometry method for determination of chlorogenic acid in coffee leaves extract. Res J Pharm Biol Chem Sci 6(5):1138–1143

CAS  Google Scholar 

Urakova IN, Pozharitskaya ON, Shikov AN, Kosman VM, Makarov VG (2008) Comparison of high performance TLC and HPLC for separation and quantification of chlorogenic acid in green coffee bean extracts. J Sep Sci 31(2):237–241. https://doi.org/10.1002/jssc.200700472

Article  CAS  PubMed  Google Scholar 

Skalicka-Woźniak K, Hajnos M, Głowniak K (2009) High-performance thin-layer chromatography combined with densitometry for quantitative analysis of chlorogenic acid in fruits of Peucedanum alsaticum L. J Planar Chromat-Mod TLC 22(4):297–300. https://doi.org/10.1556/JPC.22.2009.4.11

Article  CAS  Google Scholar 

Shahnawaz PDK, Dey A (2018) HPTLC Analysis of the antioxidant and possible antidiabetic chlorogenic acid in the in situ and in vitro populations of the low-calorie sweetener Stevia rebaudiana (Bert.) Bertoni. Anal Chem Lett 8(6):872–881. https://doi.org/10.1080/22297928.2018.1515657

Article  CAS  Google Scholar 

Darekar DP, Sheikh MV, Hate MS (2018) High performance thin layer chromatography (HPTLC) and high performance liquid chromatography (HPLC) for qualitative and quantitative analysis of chlorogenic acid in Calendula officinalis Linn. Int J Sci Res 9(10):764–767. https://doi.org/10.21275/SR201008211148

Article  Google Scholar 

Biswas S, Das A, Roy D, Roy T, Dewan D, Paul RK, Bhowmick M, Nag M (2022) Developed and validated method for the simultaneous estimation of ferulic acid and chlorogenic acid in four Indian Ananas comosus merrill cultivars through HPTLC. J Med Pharm Allied Sci 11(1):4250–4255. https://doi.org/10.55522/jmpas.V11I1.1639

Article  Google Scholar 

Creţu GE, Morlock G, Grosu AR, Nechifor AC (2013) A high-performance thin-layer chromatographic method for chlorogenic acid and hyperoside determination from berry extracts. Rom Biotechnol Lett 18(5):8657–8665

Google Scholar 

Singh AP, Singh DP, Srivastava S, Govindarajan R, Rawat AK (2007) A validated quantitative HPTLC method for analysis of biomarkers in Ficus carica L. J Planar Chromat-Mod TLC 20:437–441. https://doi.org/10.1556/JPC.20.2007.6.8

Article  CAS  Google Scholar 

Sharma A, Gill N, Kumar R (2022) Development and validation of thin layer chromatography-densitometric method for quantification of kaempferol and chlorogenic acid in methanolic extract of Dragea volubilis. Asian Pac J Health Sci 9(4):112–116. https://doi.org/10.21276/apjhs.2022.9.4.23

Article  Google Scholar 

Maleš Ž, Šarić D, Bojić M (2013) Quantitative determination of flavonoids and chlorogenic acid in the leaves of Arbutus unedo L. using thin layer chromatography. J Anal Methods Chem 22013:385473. https://doi.org/10.1155/2013/385473

Article  CAS  Google Scholar 

Orfali R, Perveen S, Aati HY, Alam P, Noman OM, Palacios J, Al-Kurbi BS, Al-Taweel AM, Khan A, Mehmood R, Khan SI (2021) High-performance thin-layer chromatography for rutin, chlorogenic acid, caffeic acid, ursolic acid, and stigmasterol analysis in Periploca aphylla extracts. Separations 8(4):44. https://doi.org/10.3390/separations8040044

Article  CAS  Google Scholar 

Pradhan SK, Gupta RC, Goel R, Preet R (2017) Simultaneous determination of chlorogenic and caffeic acid in Siegesbeckia orientalis L. (Xi Xian) by a validated high-performance thin-layer chromatographic method. J Planar Chromat-Mod TLC 30(6):516–520. https://doi.org/10.1556/1006.2017.30.6.9

Article  CAS  Google Scholar 

Mukherjee PK, Bahadur S, Chaudhary SK, Kar A, Mukherjee K (2015) Quality related safety issue-evidence-based validation of herbal medicine farm to pharma. In: Mukherjee PK (ed) evidence-based validation of herbal medicine. Elsevier, Amsterdam, pp 1–28. https://doi.org/10.1016/B978-0-12-800874-4.00001-5

Chapter  Google Scholar 

Mukherjee PK, Kar A, Biswas S, Chaudhary SK, Banerjee S (2022) Hyphenated analytical techniques for validation of herbal medicine. In: Mukherjee PK (ed) Evidence-based validation of herbal medicine, 2nd edn. Elsevier, Amsterdam, pp 811–827. https://doi.org/10.1016/B978-0-323-85542-6.00038-X

Chapter  Google Scholar 

ICH Harmonised Tripartite Guideline (2005) Validation of analytical procedures: text and methodology Q2 (R1). In: Proceedings of the International Conference on Harmonization (ICH ‘05), Geneva

Chaudhary SK, Lalvenhimi S, Biswas S, Chanda J, Kar A, Bhardwaj PK, Sharma N, Mukherjee PK (2022) High-performance thin-layer chromatography (HPTLC) method development and validation for the quantification of catechin in the hydroalcoholic extract of Parkia roxburghii seed. J Planar Chromat-Mod TLC 35(2):161–167. https://doi.org/10.1007/s00764-022-00164-6

Article  CAS  Google Scholar