Surgical Management and Denosumab for Aneurysmal Bone Cysts of the Spine in an Australian Tertiary Paediatric Centre

Rapp TB, Ward JP, Alaia MJ (2012) Aneurysmal bone cyst. J Am Acad Orthop Surg 20:233–241. https://doi.org/10.5435/JAAOS-20-04-233

Article  PubMed  Google Scholar 

Lange T, Stehling C, Frohlich B, Klingenhofer M, Kunkel P, Schneppenheim R, Escherich G, Gosheger G, Hardes J, Jurgens H, Schulte TL (2013) Denosumab: a potential new and innovative treatment option for aneurysmal bone cysts. Eur Spine J 22:1417–1422. https://doi.org/10.1007/s00586-013-2715-7

Article  PubMed  PubMed Central  Google Scholar 

Durr HR, Grahneis F, Baur-Melnyk A, Knosel T, Birkenmaier C, Jansson V, Klein A (2019) Aneurysmal bone cyst: results of an off label treatment with Denosumab. BMC Musculoskelet Disord 20:456. https://doi.org/10.1186/s12891-019-2855-y

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kurucu N, Akyuz C, Ergen FB, Yalcin B, Kosemehmetoglu K, Ayvaz M, Varan A, Aydin B, Kutluk T (2018) Denosumab treatment in aneurysmal bone cyst: evaluation of nine cases. Pediatr Blood Cancer. https://doi.org/10.1002/pbc.26926

Article  PubMed  Google Scholar 

Sciot R, Dorfman H, Brys P, Dal Cin P, De Wever I, Fletcher CD, Jonson K, Mandahl N, Mertens F, Mitelman F, Rosai J, Rydholm A, Samson I, Tallini G, Van den Berghe H, Vanni R, Willen H (2000) Cytogenetic-morphologic correlations in aneurysmal bone cyst, giant cell tumor of bone and combined lesions. a report from the CHAMP study group. Mod Pathol 13:1206–1210. https://doi.org/10.1038/modpathol.3880224

Article  CAS  PubMed  Google Scholar 

Palmerini E, Ruggieri P, Angelini A, Boriani S, Campanacci D, Milano GM, Cesari M, Paioli A, Longhi A, Abate ME, Scoccianti G, Terzi S, Trovarelli G, Franchi A, Picci P, Ferrari S, Leopardi MP, Pierini M (2018) Denosumab in patients with aneurysmal bone cysts: a case series with preliminary results. Tumori 104:344–351. https://doi.org/10.1177/0300891618784808

Article  CAS  PubMed  PubMed Central  Google Scholar 

Oliveira AM, Chou MM (2014) USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular fasciitis. Hum Pathol 45:1–11. https://doi.org/10.1016/j.humpath.2013.03.005

Article  CAS  PubMed  Google Scholar 

Park HY, Yang SK, Sheppard WL, Hegde V, Zoller SD, Nelson SD, Federman N, Bernthal NM (2016) Current management of aneurysmal bone cysts. Curr Rev Musculoskelet Med 9:435–444. https://doi.org/10.1007/s12178-016-9371-6

Article  PubMed  PubMed Central  Google Scholar 

Maximen J, Robin F, Tronchot A, Rossetti A, Ropars M, Guggenbuhl P (2022) Denosumab in the management of Aneurysmal bone cyst: a literature review. Joint Bone Spine 89:105260. https://doi.org/10.1016/j.jbspin.2021.105260

Article  CAS  PubMed  Google Scholar 

Pelle DW, Ringler JW, Peacock JD, Kampfschulte K, Scholten DJ 2nd, Davis MM, Mitchell DS, Steensma MR (2014) Targeting receptor-activator of nuclear kappaB ligand in aneurysmal bone cysts: verification of target and therapeutic response. Transl Res 164:139–148. https://doi.org/10.1016/j.trsl.2014.03.005

Article  CAS  PubMed  Google Scholar 

Won KY, Kalil RK, Kim YW, Park YK (2011) RANK signalling in bone lesions with osteoclast-like giant cells. Pathology 43:318–321. https://doi.org/10.1097/PAT.0b013e3283463536

Article  PubMed  Google Scholar 

Thomas D, Henshaw R, Skubitz K, Chawla S, Staddon A, Blay J-Y, Roudier M, Smith J, Ye Z, Sohn W, Dansey R, Jun S (2010) Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study. Lancet Oncol 11:275–280. https://doi.org/10.1016/s1470-2045(10)70010-3

Article  CAS  PubMed  Google Scholar 

Engellau J, Seeger L, Grimer R, Henshaw R, Gelderblom H, Choy E, Chawla S, Reichardt P, O’Neal M, Feng A, Jacobs I, Roberts ZJ, Braun A, Bach BA (2018) Assessment of denosumab treatment effects and imaging response in patients with giant cell tumor of bone. World J Surg Oncol 16:191. https://doi.org/10.1186/s12957-018-1478-3

Article  PubMed  PubMed Central  Google Scholar 

Chawla S, Blay JY, Rutkowski P, Le Cesne A, Reichardt P, Gelderblom H, Grimer RJ, Choy E, Skubitz K, Seeger L, Schuetze SM, Henshaw R, Dai T, Jandial D, Palmerini E (2019) Denosumab in patients with giant-cell tumour of bone: a multicentre, open-label, phase 2 study. Lancet Oncol 20:1719–1729. https://doi.org/10.1016/S1470-2045(19)30663-1

Article  CAS  PubMed  Google Scholar 

Boyce AM (2017) Denosumab: an emerging therapy in pediatric bone disorders. Curr Osteoporos Rep 15:283–292. https://doi.org/10.1007/s11914-017-0380-1

Article  PubMed  PubMed Central  Google Scholar 

Choe M, Smith V, Okcu MF, Wulff J, Gruner S, Huisman T, Venkatramani R (2021) Treatment of central giant cell granuloma in children with denosumab. Pediatr Blood Cancer 68:e28778. https://doi.org/10.1002/pbc.28778

Article  CAS  PubMed  Google Scholar 

Fisher CG, DiPaola CP, Ryken TC, Bilsky MH, Shaffrey CI, Berven SH, Harrop JS, Fehlings MG, Boriani S, Chou D, Schmidt MH, Polly DW, Biagini R, Burch S, Dekutoski MB, Ganju A, Gerszten PC, Gokaslan ZL, Groff MW, Liebsch NJ, Mendel E, Okuno SH, Patel S, Rhines LD, Rose PS, Sciubba DM, Sundaresan N, Tomita K, Varga PP, Vialle LR, Vrionis FD, Yamada Y, Fourney DR (2010) A novel classification system for spinal instability in neoplastic disease: an evidence-based approach and expert consensus from the Spine oncology study group. Spine (Phila Pa 1976) 35:E1221-1229. https://doi.org/10.1097/BRS.0b013e3181e16ae2

Article  PubMed  Google Scholar 

Vanderniet JA, Wall CL, Mullins A, London K, Lim L, Hibbert S, Briody J, Padhye B, Poon M, Biggin A, Dalla-Pozza L, Munns CF (2022) Denosumab for central giant cell granuloma in an Australian tertiary paediatric centre. Bone 159:116395. https://doi.org/10.1016/j.bone.2022.116395

Article  CAS  PubMed  Google Scholar 

Ooi HL, Briody J, Biggin A, Cowell CT, Munns CF (2013) Intravenous zoledronic acid given every 6 months in childhood osteoporosis. Horm Res Paediatr 80:179–184. https://doi.org/10.1159/000354303

Article  CAS  PubMed  Google Scholar 

Kwon BK, Tetzlaff W, Grauer JN, Beiner J, Vaccaro AR (2004) Pathophysiology and pharmacologic treatment of acute spinal cord injury. Spine J 4:451–464. https://doi.org/10.1016/j.spinee.2003.07.007

Article  PubMed  Google Scholar 

Fehlings MG, Vaccaro A, Wilson JR, Singh A, Cadotte W, Harrop JS, Aarabi B, Shaffrey C, Dvorak M, Fisher C, Arnold P, Massicotte EM, Lewis S, Rampersaud R (2012) Early versus delayed decompression for traumatic cervical spinal cord injury: results of the surgical timing in acute spinal cord injury study (STASCIS). PLoS ONE 7:e32037. https://doi.org/10.1371/journal.pone.0032037

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wilson JR, Singh A, Craven C, Verrier MC, Drew B, Ahn H, Ford M, Fehlings MG (2012) Early versus late surgery for traumatic spinal cord injury: the results of a prospective Canadian cohort study. Spinal Cord 50:840–843. https://doi.org/10.1038/sc.2012.59

Article  CAS  PubMed  Google Scholar 

Papagelopoulos PJ, Choudhury SN, Frassica FJ, Bond JR, Unni KK, Sim FH (2001) Treatment of aneurysmal bone cysts of the pelvis and sacrum. J Bone Joint Surg Am 83:1674–1681. https://doi.org/10.2106/00004623-200111000-00009

Article  CAS  PubMed  Google Scholar 

Alhumaid I, Abu-Zaid A (2019) Denosumab therapy in the management of aneurysmal bone cysts: a comprehensive literature review. Cureus 11:e3989. https://doi.org/10.7759/cureus.3989

Article  PubMed  PubMed Central  Google Scholar 

Boye K, Jebsen NL, Zaikova O, Knobel H, Londalen AM, Trovik CS, Monge OR, Hall KS (2017) Denosumab in patients with giant-cell tumor of bone in Norway: results from a nationwide cohort. Acta Oncol 56:479–483. https://doi.org/10.1080/0284186X.2016.1278305

Article  CAS  PubMed  Google Scholar 

Muheremu A, Ma Y, Huang Z, Shan H, Li Y, Niu X (2017) Diagnosing giant cell tumor of the bone using positron emission tomography/computed tomography: a retrospective study of 20 patients from a single center. Oncol Lett 14:1985–1988. https://doi.org/10.3892/ol.2017.6379

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hao K, Wang Q (2019) 18F-FDG PET/CT imaging in evaluation the efficacy of denosumab for giant cell tumor of bone. J Nucl Med 60:1279–1279

Google Scholar 

Pan KS, Boyce AM (2021) Denosumab treatment for giant cell tumors, aneurysmal bone cysts, and fibrous dysplasia-risks and benefits. Curr Osteoporos Rep 19:141–150. https://doi.org/10.1007/s11914-021-00657-z

Article  PubMed  PubMed Central  Google Scholar 

Boyce AM, Chong WH, Yao J, Gafni RI, Kelly MH, Chamberlain CE, Bassim C, Cherman N, Ellsworth M, Kasa-Vubu JZ, Farley FA, Molinolo AA, Bhattacharyya N, Collins MT (2012) Denosumab treatment for fibrous dysplasia. J Bone Miner Res 27:1462–1470. https://doi.org/10.1002/jbmr.1603

Article  CAS  PubMed  Google Scholar 

Grasemann C, Schundeln MM, Hovel M, Schweiger B, Bergmann C, Herrmann R, Wieczorek D, Zabel B, Wieland R, Hauffa BP (2013) Effects of RANK-ligand antibody (denosumab) treatment on bone turnover markers in a girl with juvenile Paget’s disease. J Clin Endocrinol Metab 98:3121–3126. https://doi.org/10.1210/jc.2013-1143

Article  CAS  PubMed  Google Scholar 

Gossai N, Hilgers MV, Polgreen LE, Greengard EG (2015) Critical hypercalcemia following discontinuation of denosumab therapy for metastatic giant cell tumor of bone. Pediatr Blood Cancer 62:1078–1080. https://doi.org/10.1002/pbc.25393

Article  PubMed  Google Scholar 

Setsu N, Kobayashi E, Asano N, Yasui N, Kawamoto H, Kawai A, Horiuchi K (2016) Severe hypercalcemia following denosumab treatment in a juvenile patient. J Bone Miner Metab 34:118–122. https://doi.org/10.1007/s00774-015-0677-z

Article  PubMed  Google Scholar 

Uday S, Gaston CL, Rogers L, Parry M, Joffe J, Pearson J, Sutton D, Grimer R, Hogler W (2018) Osteonecrosis of the jaw and rebound hypercalcemia in young people treated with denosumab for giant cell tumor of bone. J Clin Endocrinol Metab 103:596–603. https://doi.org/10.1210/jc.2017-02025

Article  PubMed 

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