Roura E, Foster S, Winklebach A, Navarro M, Thomas W, Campbell K, et al. Taste and hypertension in humans: targeting cardiovascular disease. Curr Pharm Des. 2016;22:2290–305. https://doi.org/10.2174/1381612822666160216151545.
Article CAS PubMed Google Scholar
Masenga SK, Hamooya BM, Nzala S, Kwenda G, Heimburger DC, Mutale W, et al. Patho-immune mechanisms of hypertension in HIV: a systematic and thematic review. Curr Hypertens Rep. 2019;21:56. https://doi.org/10.1007/s11906-019-0956-5.
Article CAS PubMed PubMed Central Google Scholar
Pangmekeh PJ, Awolu MM, Gustave S, Gladys T, Cumber SN. Association between highly active antiretroviral therapy (HAART) and hypertension in persons living with HIV/AIDS at the Bamenda Regional Hospital, Cameroon. Pan Afr Med J. 2019;33:87. https://doi.org/10.11604/pamj.2019.33.87.15574.
Article PubMed PubMed Central Google Scholar
Masenga SK, Elijovich F, Koethe JR, Hamooya BM, Heimburger DC, Munsaka SM, et al. Hypertension and metabolic syndrome in persons with HIV. Curr Hypertens Rep. 2020;22:78. https://doi.org/10.1007/s11906-020-01089-3.
Article PubMed PubMed Central Google Scholar
Henn IW, da Silva ROC, Chaiben CL, Fernandes Â, Naval Machado MÂ, de Lima AAS. Perception of taste in HIV-positive individuals in treatment antiretroviral: results of a case-control study. Spec Care Dentist. 2017;37:3–9. https://doi.org/10.1111/scd.12186.
Black HR. The burden of cardiovascular disease: following the link from hypertension to myocardial infarction and heart failure. Am J Hypertens. 2003;16:4S-6S. https://doi.org/10.1016/S0895-7061(03)00969-5.
Fasunla AJ, Daniel A, Nwankwo U, Kuti KM, Nwaorgu OG, Akinyinka OO. Evaluation of olfactory and gustatory function of HIV infected women. AIDS Res Treat. 2016;2016:2045383. https://doi.org/10.1155/2016/2045383.
Article CAS PubMed PubMed Central Google Scholar
•• Masenga SK, Kirabo A, Hamooya BM, Nzala S, Kwenda G, Heimburger DC, et al. HIV-positive demonstrate more salt sensitivity and nocturnal non-dipping blood pressure than HIV-negative individuals. Clin Hypertens. 2021;27. https://doi.org/10.1186/s40885-020-00160-0. This clinical trial demonstrates that the pressor response to dietary salt is higher in persons with HIV and hypertension.
Shah ASV, Stelzle D, Lee KK, Beck EJ, Alam S, Clifford S, et al. Global burden of atherosclerotic cardiovascular disease in people living with HIV: systematic review and meta-analysis. Circulation. 2018;138:1100–12. https://doi.org/10.1161/CIRCULATIONAHA.117.033369.
Article PubMed PubMed Central Google Scholar
Elvstam O, Marrone G, Engström G, Nilsson PM, Carlander C, Treutiger CJ, et al. Associations between HIV Viremia during antiretroviral therapy and cardiovascular disease. AIDS. 2022;36:1829–34. https://doi.org/10.1097/QAD.0000000000003240.
Article CAS PubMed Google Scholar
Karmous I, Plesník J, Khan AS, Šerý O, Abid A, Mankai A, et al. Orosensory detection of bitter in fat-taster healthy and obese participants: genetic polymorphism of CD36 and TAS2R38. Clin Nutr. 2018;37:313–20. https://doi.org/10.1016/j.clnu.2017.06.004.
Article CAS PubMed Google Scholar
Piovesana PDM, Sampaio KDL, Gallani MCBJ. Association between taste sensitivity and self-reported and objective measures of salt intake among hypertensive and normotensive individuals. Int Sch Res Notices. 2012;2013:e301213. https://doi.org/10.5402/2013/301213.
Murtaugh MA, Beasley JM, Appel LJ, Guenther PM, McFadden M, Greene T, et al. Relationship of sodium intake and blood pressure varies with energy intake: secondary analysis of the DASH (dietary approaches to stop hypertension)-sodium trial. Hypertension. 2018;71:858–65. https://doi.org/10.1161/HYPERTENSIONAHA.117.10602.
Article CAS PubMed Google Scholar
•• Martinelli J, Conde SR, de Araújo AR, Marcadenti A. Association between salt taste sensitivity threshold and blood pressure in healthy individuals: a cross-sectional study. Sao Paulo Med J. 2020;138:4–10. https://doi.org/10.1590/1516-3180.2019.0166.R1.02102019. In this study, they report that salt taste sensitivity is associated with increased salt intake and elevated blood pressure independent of other risk factors for hypertension.
Article PubMed PubMed Central Google Scholar
Kirabo A. A new paradigm of sodium regulation in inflammation and hypertension. Am J Physiol Regul Integr Comp Physiol. 2017;313:R706–10. https://doi.org/10.1152/ajpregu.00250.2017.
Article CAS PubMed PubMed Central Google Scholar
Elijovich F, Weinberger MH, Anderson CAM, Appel LJ, Bursztyn M, Cook NR, et al. Salt sensitivity of blood pressure. Hypertension. 2016;68:e7–46. https://doi.org/10.1161/HYP.0000000000000047.
Article CAS PubMed Google Scholar
Lindhorst J, Alexander N, Blignaut J, Rayner B. Differences in hypertension between Blacks and Whites: an overview. Cardiovasc J Afr. 2007;18:241–7.
PubMed PubMed Central Google Scholar
Morris RC, Sebastian A, Forman A, Tanaka M, Schmidlin O. Normotensive salt sensitivity. Hypertension. 1999;33:18–23. https://doi.org/10.1161/01.HYP.33.1.18.
Article CAS PubMed Google Scholar
Mishra S, Ingole S, Jain R. Salt sensitivity and its implication in clinical practice. Indian Heart J. 2018;70:556–64. https://doi.org/10.1016/j.ihj.2017.10.006.
Choi HY, Park HC, Ha SK. Salt sensitivity and hypertension: a paradigm shift from kidney malfunction to vascular endothelial dysfunction. Electrolyte Blood Press. 2015;13:7–16. https://doi.org/10.5049/EBP.2015.13.1.7.
Article CAS PubMed PubMed Central Google Scholar
Weinberger MH, Fineberg NS, Fineberg SE, Weinberger M. Salt sensitivity, pulse pressure, and death in normal and hypertensive humans. Hypertension. 2001;37:429–32. https://doi.org/10.1161/01.hyp.37.2.429.
Article CAS PubMed Google Scholar
Melis M, Mastinu M, Sollai G, Paduano D, Chicco F, Magrì S, et al. Taste changes in patients with inflammatory bowel disease: associations with PROP phenotypes and polymorphisms in the salivary protein, gustin and CD36 receptor genes. Nutrients. 2020;12:409. https://doi.org/10.3390/nu12020409.
Article CAS PubMed PubMed Central Google Scholar
•• Tapanee P, Tidwell DK, Schilling MW, Peterson DG, Tolar-Peterson T. Genetic variation in taste receptor genes (SCNN1B, TRPV1) and its correlation with the perception of saltiness in normotensive and hypertensive adults. Int J Hypertens. 2021;2021:5559831. https://doi.org/10.1155/2021/5559831. This case-control study links genetic variants in the taste receptor genes to salt taste sensitivity and hypertension risk. They further show that people with hypertension have a higher salt taste threshold than those with normotension.
Article CAS PubMed PubMed Central Google Scholar
Pilic L, Mavrommatis Y. Genetic predisposition to salt-sensitive normotension and its effects on salt taste perception and intake. Br J Nutr. 2018;120:721–31. https://doi.org/10.1017/S0007114518002027.
Article CAS PubMed Google Scholar
Diószegi J, Llanaj E, Ádány R. Genetic background of taste perception, taste preferences, and its nutritional implications: a systematic review. Front Genet. 2019;10:1272. https://doi.org/10.3389/fgene.2019.01272.
Article CAS PubMed PubMed Central Google Scholar
Gravina SA, Yep GL, Khan M. Human biology of taste. Ann Saudi Med. 2013;33:217–22. https://doi.org/10.5144/0256-4947.2013.217.
Article PubMed PubMed Central Google Scholar
Mattes RD. Fat taste in humans: is it a primary? In Fat Detection: taste, texture, and post ingestive effects; Montmayeur J-P, le Coutre J, editors; Front Neurosci; CRC Press/Taylor & Francis: Boca Raton (FL); 2010. ISBN 978-1-4200-6775-0.
Contreras RJ. Salt taste and disease. Am J Clin Nutr. 1978;31:1088–97. https://doi.org/10.1093/ajcn/31.6.1088.
Article CAS PubMed Google Scholar
• Bigiani A. Does ENaC work as sodium taste receptor in humans? Nutrients. 2020;12:1195. https://doi.org/10.3390/nu12041195. This review provides a comprehensive description of current knowledge on ENaC’s salt sensing mechanisms and its role in mediating a liking for salty food.
Article CAS PubMed PubMed Central Google Scholar
• Nomura K, Nakanishi M, Ishidate F, Iwata K, Taruno A. All-electrical Ca2+-independent signal transduction mediates attractive sodium taste in taste buds. Neuron. 2020;106:816–829.e6. https://doi.org/10.1016/j.neuron.2020.03.006. This work reveals ENaC-independent salt attraction via signal transduction mechanisms.
Article CAS PubMed Google Scholar
Shigemura N, Ohkuri T, Sadamitsu C, Yasumatsu K, Yoshida R, Beauchamp GK, et al. Amiloride-sensitive NaCl taste responses are associated with genetic variation of ENaC α-subunit in mice. Am J Physiol Regul Integr Comp Physiol. 2008;294:R66–75. https://doi.org/10.1152/ajpregu.00420.2007.
Article CAS PubMed Google Scholar
Pitzer AL, Van Beusecum JP, Kleyman TR, Kirabo A. ENaC in salt-sensitive hypertension: kidney and beyond. Curr Hypertens Rep. 2020. https://doi.org/10.1007/s11906-020-01067-9.
Article PubMed PubMed Central Google Scholar
Canessa CM, Schild L, Buell G, Thorens B, Gautschi I, Horisberger JD, et al. Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits. Nature. 1994;367:463–7. https://doi.org/10.1038/367463a0.
Article CAS PubMed Google Scholar
Huque T, Cowart BJ, Dankulich-Nagrudny L, Pribitkin EA, Bayley DL, Spielman AI, et al. Sour ageusia in two individuals implicates ion channels of the ASIC and PKD families in human sour taste perception at the anterior tongue. PLoS ONE. 2009;4:e7347. https://doi.org/10.1371/journal.pone.0007347.
Article CAS PubMed PubMed Central Google Scholar
Rossier O, Cao J, Huque T, Spielman AI, Feldman RS, Medrano JF, et al. Analysis of a human fungiform papillae CDNA library and identification of taste-related genes. Chem Senses. 2004;29:13–23. https://doi.org/10.1093/chemse/bjh002.
留言 (0)