Avogaro A, Fadini GP. Microvascular complications in diabetes: a growing concern for cardiologists. Int J Cardiol. 2019;291:29–35. https://doi.org/10.1016/j.ijcard.2019.02.030.

Article  PubMed  Google Scholar 

Bourne RRA, Jonas JB, Bron AM, Cicinelli MV, Das A, Flaxman SR, et al. Prevalence and causes of vision loss in high-income countries and in Eastern and Central Europe in 2015: magnitude, temporal trends and projections. Br J Ophthalmol. 2018;102:575–85. https://doi.org/10.1136/bjophthalmol-2017-311258.

Article  PubMed  Google Scholar 

Jackson W. Improving diabetic retinopathy screening. Diabetes Care. 2002;25:1477–8. https://doi.org/10.2337/diacare.25.8.1477.

Article  PubMed  Google Scholar 

Kashim RM, Newton P, Ojo O. Diabetic retinopathy screening: a systematic review on patients’ non-attendance. Int J Environ Res Public Health. 2018;15:157. https://doi.org/10.3390/ijerph15010157.

Article  PubMed  PubMed Central  Google Scholar 

Bebu I, Lachin JM. Optimal screening schedules for disease progression with application to diabetic retinopathy. Biostatistics. 2018;19:1–13. https://doi.org/10.1093/biostatistics/kxx009.

Article  PubMed  Google Scholar 

Miller DJ, Cascio MA, Rosca MG. Diabetic retinopathy: the role of mitochondria in the neural retina and microvascular disease. Antioxidants (Basel). 2020;9:905. https://doi.org/10.3390/antiox9100905.

Article  CAS  PubMed  Google Scholar 

Al-Shabrawey M, Smith S. Prediction of diabetic retinopathy: role of oxidative stress and relevance of apoptotic biomarkers. EPMA J. 2010;1:56–72. https://doi.org/10.1007/s13167-010-0002-9.

Article  PubMed  PubMed Central  Google Scholar 

Hendrick AM, Gibson MV, Kulshreshtha A. Diabetic retinopathy. Prim Care. 2015;42:451–64. https://doi.org/10.1016/j.pop.2015.05.005.

Article  PubMed  Google Scholar 

Golubnitschaja O, Potuznik P, Polivka J, Pesta M, Kaverina O, Pieper CC, et al. Ischemic stroke of unclear aetiology: a case-by-case analysis and call for a multi-professional predictive, preventive and personalised approach. EPMA J. 2022;13:535–45. https://doi.org/10.1007/s13167-022-00307-z.

Article  PubMed  PubMed Central  Google Scholar 

Wang Z, Cao D, Zhuang X, Yao J, Chen R, Chen Y, et al. Diabetic retinopathy may be a predictor of stroke in patients with diabetes mellitus. J Endocr Soc. 2022;6:bvac097. https://doi.org/10.1210/jendso/bvac097.

Eriksson MI, Summanen P, Gordin D, Forsblom C, Shams S, Liebkind R, et al. Cerebral small-vessel disease is associated with the severity of diabetic retinopathy in type 1 diabetes. BMJ Open Diabetes Res Care. 2021;9:e002274. https://doi.org/10.1136/bmjdrc-2021-002274.

Article  PubMed  PubMed Central  Google Scholar 

Wat N, Wong RL, Wong IY. Associations between diabetic retinopathy and systemic risk factors. Hong Kong Med J. 2016;22:589–99. https://doi.org/10.12809/hkmj164869.

Article  CAS  PubMed  Google Scholar 

Animaw W, Seyoum Y. Increasing prevalence of diabetes mellitus in a developing country and its related factors. PLoS One. 2017;12:e0187670. https://doi.org/10.1371/journal.pone.0187670.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tinajero MG, Malik VS. An update on the epidemiology of type 2 diabetes: a global perspective. Endocrinol Metab Clin North Am. 2021;50:337–55. https://doi.org/10.1016/j.ecl.2021.05.013.

Article  PubMed  Google Scholar 

Lin X, Xu Y, Pan X, Xu J, Ding Y, Sun X, et al. Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025. Sci Rep. 2020;10:14790. https://doi.org/10.1038/s41598-020-71908-9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khan MAB, Hashim MJ, King JK, Govender RD, Mustafa H, Al KJ. Epidemiology of type 2 diabetes - global burden of disease and forecasted trends. J Epidemiol Glob Health. 2020;10:107–11. https://doi.org/10.2991/jegh.k.191028.001.

Article  PubMed  PubMed Central  Google Scholar 

International Diabetes Federation IDF Diabetes Atlas 10th, Brussels, Belgium, International Diabetes Federation 2021.

Khalid M, Petroianu G, Adem A. Advanced glycation end products and diabetes mellitus: mechanisms and perspectives. Biomolecules. 2022;12:542. https://doi.org/10.3390/biom12040542.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stitt AW. The role of advanced glycation in the pathogenesis of diabetic retinopathy. Exp Mol Pathol. 2003;75:95–108. https://doi.org/10.1016/s0014-4800(03)00035-2.

Article  CAS  PubMed  Google Scholar 

Cade WT. Diabetes-related microvascular and macrovascular diseases in the physical therapy setting. Phys Ther. 2008;88:1322–35. https://doi.org/10.2522/ptj.20080008.

Article  PubMed  PubMed Central  Google Scholar 

Ling W, Huang Y, Huang Y-M, Fan R-R, Sui Y, Zhao H-L. Global trend of diabetes mortality attributed to vascular complications, 2000–2016. Cardiovasc Diabetol. 2020;19:182. https://doi.org/10.1186/s12933-020-01159-5.

Article  PubMed  PubMed Central  Google Scholar 

Tönnies T, Röckl S, Hoyer A, Heidemann C, Baumert J, Du Y, et al. Projected number of people with diagnosed type 2 diabetes in Germany in 2040. Diabet Med. 2019;36:1217–25. https://doi.org/10.1111/dme.13902.

Article  PubMed  Google Scholar 

Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition. Diabetes Res Clin Pract. 2019;157:107843. https://doi.org/10.1016/j.diabres.2019.107843.

Pradeepa R, Mohan V. Epidemiology of type 2 diabetes in India. Indian J Ophthalmol. 2021;69:2932–8. https://doi.org/10.4103/ijo.IJO_1627_21.

Article  PubMed  PubMed Central  Google Scholar 

Jacobs E, Hoyer A, Brinks R, Icks A, Kuß O, Rathmann W. Healthcare costs of type 2 diabetes in Germany. Diabet Med. 2017;34:855–61. https://doi.org/10.1111/dme.13336.

Article  CAS  PubMed  Google Scholar 

Lynch JL, Barrientos-Pérez M, Hafez M, Jalaludin MY, Kovarenko M, Rao PV, et al. Country-specific prevalence and incidence of youth-onset type 2 diabetes: a narrative literature review. Ann Nutr Metab. 2020;76:289–96. https://doi.org/10.1159/000510499.

Article  CAS  PubMed  Google Scholar 

Shukla UV, Tripathy K. Diabetic retinopathy. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2022.

Alemu Mersha G, Alimaw YA, Woredekal AT. Prevalence of diabetic retinopathy among diabetic patients in Northwest Ethiopia-a cross sectional hospital based study. PLoS One. 2022;17:e0262664. https://doi.org/10.1371/journal.pone.0262664.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Romero-Aroca P, López-Galvez M, Martinez-Brocca MA, Pareja-Ríos A, Artola S, Franch-Nadal J, et al. Changes in the epidemiology of diabetic retinopathy in Spain: a systematic review and meta-analysis. Healthcare (Basel). 2022;10:1318. https://doi.org/10.3390/healthcare10071318v.

Article  PubMed  Google Scholar 

Teo ZL, Tham Y-C, Yu M, Chee ML, Rim TH, Cheung N, et al. Global Prevalence of diabetic retinopathy and projection of burden through 2045: systematic review and meta-analysis. Ophthalmology. 2021;128:1580–91. https://doi.org/10.1016/j.ophtha.2021.04.027.

Article  PubMed  Google Scholar 

Pradeepa R, Surendar J, Indulekha K, Chella S, Anjana RM, Mohan V. Relationship of diabetic retinopathy with coronary artery disease in Asian Indians with type 2 diabetes: the Chennai Urban Rural Epidemiology Study (CURES) Eye Study–3. Diabetes Technol Ther. 2015;17:112–8. https://doi.org/10.1089/dia.2014.0141.

Article  CAS  PubMed  Google Scholar 

Tan GS, Gan A, Sabanayagam C, Tham YC, Neelam K, Mitchell P, et al. Ethnic differences in the prevalence and risk factors of diabetic retinopathy: the Singapore Epidemiology of Eye Diseases Study. Ophthalmology. 2018;125:529–36. https://doi.org/10.1016/j.ophtha.2017.10.026.

Article  PubMed  Google Scholar 

Yang Q-H, Zhang Y, Zhang X-M, Li X-R. Prevalence of diabetic retinopathy, proliferative diabetic retinopathy and non-proliferative diabetic retinopathy in Asian T2DM patients: a systematic review and Meta-analysis. Int J Ophthalmol. 2019;12:302–11. https://doi.org/10.18240/ijo.2019.02.19.

Article  PubMed  PubMed Central  Google Scholar 

Cheloni R, Gandolfi SA, Signorelli C, Odone A. Global prevalence of diabetic retinopathy: protocol for a systematic review and meta-analysis. BMJ Open. 2019;9:e022188. https://doi.org/10.1136/bmjopen-2018-022188.

Article  PubMed  PubMed Central  Google Scholar 

The world report on vision, World Health Organization (WHO), 2019.

Wykoff CC, Khurana RN, Nguyen QD, Kelly SP, Lum F, Hall R, et al. Risk of blindness among patients with diabetes and newly diagnosed diabetic retinopathy. Diabetes Care. 2021;44:748–56. https://doi.org/10.2337/dc20-0413.

Article  PubMed  PubMed Central  Google Scholar 

Wang LZ, Cheung CY, Tapp RJ, Hamzah H, Tan G, Ting D, et al. Availability and variability in guidelines on diabetic retinopathy screening in Asian countries. Br J Ophthalmol. 2017;101:1352–60. https://doi.org/10.1136/bjophthalmol-2016-310002.

Article  PubMed  Google Scholar 

Resnikoff S, Pascolini D, Etya’ale D, Kocur I, Pararajasegaram R, Pokharel GP, et al. Global data on visual impairment in the year 2002. Bull World Health Organ. 2004;82:844–51.

Pandova MG. Diabetic Retinopathy and Blindness: an epidemiological overview. In: Giudice GL, Catalá A, editors. Visual impairment and blindness – what we know and what we have to know. IntechOpen; 2019. https://doi.org/10.5772/intechopen.88756.

GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392:1789–858. https://doi.org/10.1016/S0140-6736(18)32279-7.

Lin K-Y, Hsih W-H, Lin Y-B, Wen C-Y, Chang T-J. Update in the epidemiology, risk factors, screening, and treatment of diabetic retinopathy. J Diabetes Investig. 2021;12:1322–5. https://doi.org/10.1111/jdi.13480.

Article  PubMed  PubMed Central  Google Scholar 

Klein R, Knudtson MD, Lee KE, Gangnon R, Klein BEK. The Wisconsin Epidemiologic Study of Diabetic Retinopathy: XXII the twenty-five-year progression of retinopathy in persons with type 1 diabetes. Ophthalmology. 2008;115:1859–68. https://doi.org/10.1016/j.ophtha.2008.08.023.

Article  Pub