Proteome analysis reveals novel serum biomarkers for Henoch-Schönlein purpura in Chinese children

Keywords

Early diagnosis

Henoch-Schönlein purpura

Mass spectrometry

Serum biomarker

AbbreviationsHSP

Henoch-Schönlein purpura

HSPN

Henoch-Schönlein purpura nephritis

FGA

isoform 1 of fibrinogen alpha chain

C4A

complement C4-A precursor

MB-WCX

magnetic bead–based weak cation exchange

WBC

white blood cell count

N/L

ratio of neutrophils to lymphocytes

P/L

ratio of platelets to lymphocytes

FOBT

fecal occult blood test

NAB-HSP

HSP nonabdominal type

FCGRT

Fc gamma receptor and transporter

SLC9A3R1

solute carrier family 9 isoform A3 regulatory Factor 1

FGG

fibrinogen gamma chain

SLC9A1

solute carrier family 9 member A1

ICAM1

intercellular adhesion molecule 1

CFTR

cystic fibrosis transmembrane conductance regulator

SERPINC1

serpin family C member 1

Data availability

All raw MS files have been deposited to the ProteomeXchange Consortium (http://proteomecentral. proteomexchange.org) via the iProX partner repository with the dataset identifier PXD032897.

© 2023 The Author(s). Published by Elsevier B.V.

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