Gastric Alimetry impacts the management pathway of chronic gastroduodenal disorders

Abstract

Background Gastric Alimetry is a new diagnostic tool using non-invasive gastric electrical mapping and symptom logging to identify patient subgroups. This study aimed to propose an initial framework for Gastric Alimetry implementation in the routine management of gastroduodenal disorders, and assess its impact on diagnosis and management.

Methods Gastric Alimetry using standard tests (30-min fasted, ~480kCal meal, followed by 4-hr postprandial recording with concurrent symptom logging) was applied to patients presenting with gastroduodenal symptoms.

Results Overall, 50 patients were evaluated with Gastric Alimetry. The test aided management decisions in 78% of patients (39/50) and aided a change in diagnosis in 40% (20/50), predominantly from a motility disorder to disorders of gut-brain interaction (DGBI). Changes in invasive nutritional support occurred in 18% (9/50).

Conclusion Gastric Alimetry impacted care in most patients in this first series. Further work to inform clinical utility is now a priority.

Competing Interest Statement

The authors have declared no competing interest.

Funding Statement

The Health Research Council of New Zealand funded this work

Author Declarations

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Yes

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

Auckland Health Research Ethics Committee of University of AUckland gave ethical approval for this work

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

Yes

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

Yes

I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.

Yes

Footnotes

Conflicts of interest: The authors have no conflicts of interest to declare.

Funding statement: This project was supported by the Health Research Council of New Zealand.

Data availability statement: Data used for analysis will be made available upon reasonable request, conditional on ethical approvals.

Data Availability

All data produced in the present study are available upon reasonable request to the authors

留言 (0)

沒有登入
gif