GENOTYPE - PHENOTYPE CORRELATIONS IN GRAVES’ DISEASE

AbbreviationsCAS

clinical activity score

CD

cluster of differentiation

CLTA-4

cytotoxic T cell antigen 4

DNMT

DNA methyltransferase

GH

Graves’ hyperthyroidism

GNAS

guanine nucleotide binding protein, alpha stimulating

GWAS

genome wide association study

HLA

human leukocyte antigen

MHC

major histocompatibility complex

miRNA

micro ribonucleic acid

PTPN

protein tyrosine phosphatase non-receptor

SNP

single nucleotide polymorphism

Tg

thyroglobulin (TG, thyroglobulin gene)

TRAb

thyrotropin receptor autoantibodies

TSHR

thyroid stimulating hormone receptor

Keywords

Graves’ disease

genotype-phenotype correlation

HLA antigen

polymorphism

hyperthyroidism

orbitopathy

autoimmunity

© 2023 The Author(s). Published by Elsevier Ltd.

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