Associations between N-Acetylaspartate and white matter integrity in individuals with schizophrenia and unaffected relatives

Means and SD are estimated marginal means unless otherwise stated. In the visual cortex (Figure 3A), there was a significant effect of group (F (2, 53) = 7.304, p = 0.002, ηp2 = 0.216). PSZ had significantly lower NAA levels (m = 8.081, SD = 0.93, p = 0.002) than HC (m = 9.205, SD = 0.87, d = 1.248) after controlling for age and proportion of gray matter in the voxel. NAA levels of REL (mean = 8.687, SD = 0.92) did not differ from PSZ (p = 0.299, d = 0.66) or HC (p = 0.217, d = 0.58). There was

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