Novel Approach Self Nanoemulsifying Drug Delivery System: A Review

Advances in Pharmacology and Pharmacy Vol. 11(2), pp. 131 - 139
DOI: 10.13189/app.2023.110205
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Jyotsana Suyal 1,*, Bhavna Kumar 1, Vikas Jakhmola 2
1 School of Pharmacy, DIT University, Mussoorie Road, Dehradun, Uttarakhand, India
2 Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, Uttarakhand, India

ABSTRACT

The self-nanoemulsifying drug delivery system is solitarily the most frequent dosage form for administering drug molecules towards the target region in the pharmaceutical industry. It has gotten a lot of interest in the current scenario because of its budding applications in various industries. In the pharmaceutical business, self-nanoemulsifying drug delivery systems have been used to distribute medications via oral, topical, and parenteral routes. SNEDDS are submicron-sized emulsions being researched as drug carriers to improve therapeutic agent delivery. Due to their tiny droplets, elevated solubility ability, broad interfacial region, reduced consistency, transparent or semi-transparent emergence, & remarkable kinetic constancy, self-nanoemulsifying medicines are meant for an extensive choice of application. Through a combination of a water-insoluble lipid phase with a high-stress aqueous phase, these emulsions may be manufactured in huge quantities quickly. These are created using surfactants, co-surfactants, and co-solvents. In BCS class II and IV drugs, the self-nanoemulsifying drug delivery system is useful in favor of increasing the water solubility of water-soluble pharmaceuticals. In this review, various aspects of the self-nanoemulsifying drug delivery system are highlighted, including method of preparation, characterization techniques such as particle size, zeta potential, polydispersity, drug content, advantages, disadvantages, and a particular importance on various applications of SNEDDS in different areas, such as cancer treatment, drug targeting, and as a vehicle for transdermal drug delivery.

KEYWORDS
Self-nanoemulsifying Drug Delivery System, Co-solvent, Surface-active Agents, Emulsified Oil, Applications

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Jyotsana Suyal , Bhavna Kumar , Vikas Jakhmola , "Novel Approach Self Nanoemulsifying Drug Delivery System: A Review," Advances in Pharmacology and Pharmacy, Vol. 11, No. 2, pp. 131 - 139, 2023. DOI: 10.13189/app.2023.110205.

(b). APA Format:
Jyotsana Suyal , Bhavna Kumar , Vikas Jakhmola (2023). Novel Approach Self Nanoemulsifying Drug Delivery System: A Review. Advances in Pharmacology and Pharmacy, 11(2), 131 - 139. DOI: 10.13189/app.2023.110205.

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