GAH treatment improves mental health in transgender adolescents

Results from a prospective study to assess psychosocial functioning in transgender and non-binary young people who received gender-affirming hormone (GAH) treatment were published in the New England Journal of Medicine. Overall, 315 participants (including transmasculine, transfeminine and non-binary individuals) aged 12–20 years were enrolled in the study. Psychosocial status was assessed through four validated instruments at 6, 12, 18 and 24 months after treatment start. Results from this study showed a reduction in depression and anxiety symptoms, and an increase in positive affect and life satisfaction after GAH treatment. The mechanism underlying this psychosocial well-being seems to be appearance congruence, which substantially improved after 2 years of GAH therapy.

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