Heller, C. H. & Clermont, Y. Kinetics of the germinal epithelium in man. Recent. Prog. Horm. Res. 20, 545–575 (1964).
Suarez, S. S. & Pacey, A. A. Sperm transport in the female reproductive tract. Hum. Reprod. Update 12, 23–37 (2006).
Agarwal, A., Mulgund, A., Hamada, A. & Chyatte, M. R. A unique view on male infertility around the globe. Reprod. Biol. Endocrinol. 13, 37 (2015).
Wang, J. & Sauer, M. V. In vitro fertilization (IVF): a review of 3 decades of clinical innovation and technological advancement. Ther. Clin. Risk Manag. 2, 355–364 (2006).
Practice Committee of the American Society for Reproductive Medicine. Diagnostic evaluation of the infertile male: a committee opinion. Fertil. Steril. 103, e18–e25 (2015).
Vincent, M. C. et al. Cytogenetic investigations of infertile men with low sperm counts: a 25-year experience. J. Androl. 23, 18–22 (2002). discussion 44–45.
Jungwirth, A. et al. European Association of Urology guidelines on male infertility: the 2012 update. Eur. Urol. 62, 324–332 (2012).
Flannigan, R. K. & Schlegel, P. N. Microdissection testicular sperm extraction: preoperative patient optimization, surgical technique, and tissue processing. Fertil. Steril. 111, 420–426 (2019).
Chiba, K., Enatsu, N. & Fujisawa, M. Management of non-obstructive azoospermia. Reprod. Med. Biol. 15, 165–173 (2016).
Achermann, A. P. P., Pereira, T. A. & Esteves, S. C. Microdissection testicular sperm extraction (micro-TESE) in men with infertility due to nonobstructive azoospermia: summary of current literature. Int. Urol. Nephrol. 53, 2193–2210 (2021).
Ghieh, F., Mitchell, V., Mandon-Pepin, B. & Vialard, F. Genetic defects in human azoospermia. Basic. Clin. Androl. 29, 4 (2019).
Meistrich, M. L. Male gonadal toxicity. Pediatr. Blood Cancer 53, 261–266 (2009).
Del-Pozo-Lerida, S. et al. Preservation of fertility in patients with cancer (Review). Oncol. Rep. 41, 2607–2614 (2019).
Keros, V. et al. Methods of cryopreservation of testicular tissue with viable spermatogonia in pre-pubertal boys undergoing gonadotoxic cancer treatment. Hum. Reprod. 22, 1384–1395 (2007).
Mirzapour, T., Movahedin, M., Koruji, M. & Nowroozi, M. R. Xenotransplantation assessment: morphometric study of human spermatogonial stem cells in recipient mouse testes. Andrologia 47, 626–633 (2015).
Hou, M., Andersson, M., Eksborg, S., Soder, O. & Jahnukainen, K. Xenotransplantation of testicular tissue into nude mice can be used for detecting leukemic cell contamination. Hum. Reprod. 22, 1899–1906 (2007).
Sato, Y. et al. Xenografting of testicular tissue from an infant human donor results in accelerated testicular maturation. Hum. Reprod. 25, 1113–1122 (2010).
Schlatt, S. et al. Limited survival of adult human testicular tissue as ectopic xenograft. Hum. Reprod. 21, 384–389 (2006).
Jahnukainen, K., Hou, M., Petersen, C., Setchell, B. & Soder, O. Intratesticular transplantation of testicular cells from leukemic rats causes transmission of leukemia. Cancer Res. 61, 706–710 (2001).
Sadri-Ardekani, H. et al. Eliminating acute lymphoblastic leukemia cells from human testicular cell cultures: a pilot study. Fertil. Steril. 101, 1072–1078.e1 (2014).
Sadri-Ardekani, H. & Atala, A. Testicular tissue cryopreservation and spermatogonial stem cell transplantation to restore fertility: from bench to bedside. Stem Cell Res. Ther. 5, 68 (2014).
Jahnukainen, K., Ehmcke, J., Nurmio, M. & Schlatt, S. Autologous ectopic grafting of cryopreserved testicular tissue preserves the fertility of prepubescent monkeys that receive sterilizing cytotoxic therapy. Cancer Res. 72, 5174–5178 (2012).
Sato, T. et al. In vitro production of functional sperm in cultured neonatal mouse testes. Nature 471, 504–507 (2011).
Sato, T. et al. Testis tissue explantation cures spermatogenic failure in c-Kit ligand mutant mice. Proc. Natl Acad. Sci. USA 109, 16934–16938 (2012).
Neto, F. T., Bach, P. V., Najari, B. B., Li, P. S. & Goldstein, M. Spermatogenesis in humans and its affecting factors. Semin. Cell Dev. Biol. 59, 10–26 (2016).
Kanatsu-Shinohara, M. & Shinohara, T. Spermatogonial stem cell self-renewal and development. Annu. Rev. Cell Dev. Bi 29, 163–187 (2013).
Singh, R. & Hansen, D. Regulation of the balance between proliferation and differentiation in germ line stem cells. Results Probl. Cell Differ. 59, 31–66 (2017).
Paniagua, R. & Nistal, M. Morphological and histometric study of human spermatogonia from birth to the onset of puberty. J. Anat. 139, 535–552 (1984).
Amann, R. P. The cycle of the seminiferous epithelium in humans: a need to revisit. J. Androl. 29, 469–487 (2008).
Goossens, E. & Tournaye, H. Adult stem cells in the human testis. Semin. Reprod. Med. 31, 39–48 (2013).
Clermont, Y. Spermatogenesis in man. A study of the spermatogonial population. Fertil. Steril. 17, 705–721 (1966).
van Alphen, M. M., van de Kant, H. J. & de Rooij, D. G. Repopulation of the seminiferous epithelium of the rhesus monkey after X irradiation. Radiat. Res. 113, 487–500 (1988).
Guo, J. et al. The adult human testis transcriptional cell atlas. Cell Res. 28, 1141–1157 (2018).
Guo, J. et al. The dynamic transcriptional cell atlas of testis development during human puberty. Cell Stem Cell 26, 262–276.e4 (2020).
Ehmcke, J. & Schlatt, S. A revised model for spermatogonial expansion in man: lessons from non-human primates. Reproduction 132, 673–680 (2006).
Mruk, D. D. & Cheng, C. Y. The mammalian blood-testis barrier: its biology and regulation. Endocr. Rev. 36, 564–591 (2015).
Pelletier, R. M. The blood-testis barrier: the junctional permeability, the proteins and the lipids. Prog. Histochem. Cytochem. 46, 49–127 (2011).
Gerton, J. L. & Hawley, R. S. Homologous chromosome interactions in meiosis: diversity amidst conservation. Nat. Rev. Genet. 6, 477–487 (2005).
Hess, R. A. & de Franca, L. R. in Molecular Mechanisms in Spermatogenesis. Advances in Experimental Medicine and Biology Vol. 636 (ed. Cheng, C. Y.) 1–15 (Springer, 2009).
Clermont, Y. & Leblond, C. P. Spermiogenesis of man, monkey, ram and other mammals as shown by the periodic acid-Schiff technique. Am. J. Anat. 96, 229–253 (1955).
Oko, R. & Sutovsky, P. Biogenesis of sperm perinuclear theca and its role in sperm functional competenc and fertilization. J. Reprod. Immunol. 83, 2–7 (2009).
Foresta, C., Zorzi, M., Rossato, M. & Varotto, A. Sperm nuclear instability and staining with aniline blue: abnormal persistence of histones in spermatozoa in infertile men. Int. J. Androl. 15, 330–337 (1992).
Zhao, M. et al. Transition nuclear proteins are required for normal chromatin condensation and functional sperm development. Genesis 38, 200–213 (2004).
Wang, T., Gao, H., Li, W. & Liu, C. Essential role of histone replacement and modifications in male fertility. Front. Genet. 10, 962 (2019).
Gur, Y. & Breitbart, H. Protein synthesis in sperm: dialog between mitochondria and cytoplasm. Mol. Cell Endocrinol. 282, 45–55 (2008).
Breucker, H., Schafer, E. & Holstein, A. F. Morphogenesis and fate of the residual body in human spermiogenesis. Cell Tissue Res. 240, 303–309 (1985).
Tesarik, J. et al. Differentiation of spermatogenic cells during in-vitro culture of testicular biopsy samples from patients with obstructive azoospermia: effect of recombinant follicle stimulating hormone. Hum. Reprod. 13, 2772–2781 (1998).
Tesarik, J., Guido, M., Mendoza, C. & Greco, E. Human spermatogenesis in vitro: respective effects of follicle-stimulating hormone and testosterone on meiosis, spermiogenesis, and Sertoli cell apoptosis. J. Clin. Endocrinol. Metab. 83, 4467–4473 (1998).
Tesarik, J., Bahceci, M., Ozcan, C., Greco, E. & Mendoza, C. Restoration of fertility by in-vitro spermatogenesis. Lancet 353, 555–556 (1999).
Cremades, N., Bernabeu, R., Barros, A. & Sousa, M. In-vitro maturation of round spermatids using co-culture on vero cells. Hum. Reprod. 14, 1287–1293 (1999).
Tanaka, A. et al. Completion of meiosis in human primary spermatocytes through in vitro coculture with vero cells. Fertil. Steril. 79, 795–801 (2003).
Sato, T. et al. In vitro spermatogenesis in explanted adult mouse testis tissues. PLoS ONE https://doi.org/10.1371/journal.pone.0130171 (2015).
Komeya, M. et al. Long-term ex vivo maintenance of testis tissues producing fertile sperm in a microfluidic device. Sci. Rep. 6, 21472 (2016).
Matsumura, T. et al. Rat in vitro spermatogenesis promoted by chemical supplementations and oxygen-tension control. Sci. Rep. 11, 3458 (2021).
Sanjo, H. et al. In vitro mouse spermatogenesis with an organ culture method in chemically defined medium. PLoS ONE 13, e0192884 (2018).
Sanjo, H. et al. Antioxidant vitamins and lysophospholipids are critical for inducing mouse spermatogenesis under organ culture conditions. FASEB J. 34, 9480–9497 (2020).
Yamanaka, H. et al. A monolayer microfluidic device supporting mouse spermatogenesis with improved visibility. Biochem. Biophys. Res. Commun. 500, 885–891 (2018).
Boitani, C., Politi, M. G. & Menna, T. Spermatogonial cell proliferation in organ culture of immature rat testis. Biol. Reprod. 48, 761–767 (1993).
Hue, D. et al. Meiotic differentiation of germinal cells in three-week cultures of whole cell population from rat seminiferous tubules. Biol. Reprod. 59, 379–387 (1998).
Le Magueresse-Battistoni, B., Gerard, N. & Jegou, B. Pachytene spermatocytes can achieve meiotic process in vitro. Biochem. Biophys. Res. Commun. 179, 1115–1121 (1991).
Marh, J., Tres, L. L., Yamazaki, Y., Yanagimachi, R. & Kierszenbaum, A. L. Mouse round spermatids developed in vitro from preexisting spermatocytes can produce normal offspring by nuclear injection into in vivo-developed mature oocytes. Biol. Reprod. 69, 169–176 (2003).
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