Macular Choroidal Thickness and Choriocapillaris Vessel Density Alterations in Type 2 Diabetics with High Myopia

Research Article

Open Access Gateway Su R. · Qi Z. · Tan X.
Abstract

Introduction: The purpose of this study was to investigate the change of macular choroidal thickness and choriocapillaris vessel density in type 2 diabetic with high myopia. Methods: This cross-sectional study recruited a total of 182 patients (182 eyes) in the Affiliated Hospital of Chengde Medical University between January 2018 and December 2021, including myopia+diabetes patients (40 eyes), T2D patients without myopia patients (47 eyes), myopia patients (45 eyes) and healthy volunteers (50 eyes). The choroidal thickness and choriocapillaris vessel density of macular were measured in all subjects by optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA). Results: The choroidal thickness in myopic, diabetes, myopia+diabetes groups were statistically significantly lower than that in control group (p 0.05). Further pairwise comparisons showed that the choriocapillaris thicknesses in myopia+diabetes group were statistically significantly lower than that in myopia group (p 0.05). Conclusion: The choroidal thickness of the patients with high myopia and diabetes (without DR)was significantly lower than that of normal people and diabetic patients, but the choriocapillaris vessel density was not significantly different from that of normal people, which may be one of the protective mechanisms of high myopia against DR.

The Author(s). Published by S. Karger AG, Basel

Article / Publication Details Open Access License / Drug Dosage / Disclaimer This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC). Usage and distribution for commercial purposes requires written permission. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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