LUNG Year in Review: 2022

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O’Driscoll JM et al (2022) Undiagnosed chronic obstructive pulmonary disease is highly prevalent in patients referred for dobutamine stress echocardiography with shortness of breath. Lung 200(1):41–48

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Rahman HH, Niemann D, Munson-McGee SH (2022) Urinary metals, arsenic, and polycyclic aromatic hydrocarbon exposure and risk of self-reported emphysema in the US adult population. Lung 200(2):237–249

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Cao P et al (2022) Serum 8-hydroxy-2’-deoxyguanosine predicts severity and prognosis of patients with acute exacerbation of chronic obstructive pulmonary disease. Lung 200(1):31–39

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Chen Z et al (2022) Serum creatinine/cystatin C ratio as a predictor of in-hospital mortality in patients hospitalized with acute exacerbation of chronic obstructive pulmonary disease. Lung 200(5):609–617

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Golpe R et al (2022) Trajectories of severe exacerbations of chronic obstructive pulmonary disease and their relationship with mortality risk. Lung 200(5):601–607

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Ben Anes A et al (2022) Plasma lipid profiling identifies phosphatidylcholine 34:3 and triglyceride 52:3 as potential markers associated with disease severity and oxidative status in chronic obstructive pulmonary disease. Lung 200(4):495–503

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Kendra M et al (2022) Decreasing hospital readmissions utilizing an evidence-based COPD care bundle. Lung 200(4):481–486

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Pini L et al (2022) Acute effect of bronchodilator on intrathoracic airway wall compliance in COPD patients. Lung 200(4):473–480

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Sillen MJH et al (2022) Effects of pulmonary rehabilitation including inspiratory muscle training in patients with chronic obstructive pulmonary disease after stratification by the degree of static hyperinflation. Lung 200(4):487–494

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Mei X et al (2022) Poly I: C exacerbates airway inflammation and remodeling in cigarette smoke-exposed mice. Lung 200(6):677–686

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Garantziotis S (2022) Adding (viral) insult to (smoke) injury may prolong COPD changes after smoking cessation (editorial). Lung 200(6):671–672

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Rizzo JA et al (2022) Ventilation rates achieved in eucapnic voluntary hyperpnea challenge and exercise-induced bronchoconstriction diagnosis in young patients with asthma. Lung 200(2):229–236

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Fang XM et al (2022) Endogenous adenosine 5’-monophosphate, but not acetylcholine or histamine, is associated with asthma control, quality of life, and exacerbations. Lung 200(5):579–589

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Pham DD et al (2022) Different impacts of blood and sputum eosinophil counts on lung function and clinical outcomes in asthma: findings from the COREA cohort. Lung 200(6):697–706

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Chan R, Lipworth BJ (2022) Impact of biologic therapy on the small airways asthma phenotype. Lung 200(6):691–696

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Alachraf K et al (2022) Social determinants of emergency department visits in mild compared to moderate and severe asthma. Lung 200(2):221–226

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Holmes J, Heaney LG, McGarvey LPA (2022) Objective and subjective measurement of cough in asthma: a systematic review of the literature. Lung 200(2):169–178

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Chiba Y et al (2022) Hyperresponsiveness to extracellular acidification-mediated contraction in isolated bronchial smooth muscles of murine experimental asthma. Lung 200(5):591–599

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Castellani C, Castellani H, Benn BS (2022) Transbronchial lung cryobiopsy is safe and effective for diagnosing acutely ill hospitalized patients with new diffuse parenchymal lung disease. Lung 200(2):153–159

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Walscher J et al (2022) Comparison of a 22G crown-cut needle with a conventional 22G needle with EBUS guidance in diagnosis of sarcoidosis. Lung 200(5):633–641

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Torii A et al (2022) EUS-B-FNA enhances the diagnostic yield of EBUS bronchoscope for intrathoracic lesions. Lung 200(5):643–648

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Oberg CL et al (2022) Novel robotic-assisted cryobiopsy for peripheral pulmonary lesions. Lung 200(6):737–745

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Nakashima K et al (2022) Sulfated glycans recognized by S1 monoclonal antibody can serve as a diagnostic marker for malignant pleural mesothelioma. Lung 200(3):339–346

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Zhang GH, Liu YJ, Ji MD (2022) Risk factors, prognosis, and a new nomogram for predicting cnacer-specific survival among lung cancer patinets with brain metastasis: a retrospective study based on SEER. Lung 200(1):83–93

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Wang T, Zhu X, Wang K (2022) CircMIIP contributes to non-small cell lung cancer progression by binding miR-766-5p to upregulate FAM83A expression. Lung 200(1):107–117

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Feng Y et al (2022) Genomic analysis reveals the prognostic and immunotherapeutic response characteristics of ferroptosis in lung squamous cell carcinoma. Lung 200(3):381–392

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Bertoglio P et al (2022) Impact of high-grade patterns in early-stage lung adenocarcinoma: a multicentric analysis. Lung 200(5):649–660

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Shen F et al (2022) Prognostic value of geriatric nutritional risk index for patients with non-small cell lung cancer: a systematic review and meta-analysis. Lung 200(5):661–669

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Avrillon V et al (2022) Nationwide real-life safety and treatment exposure data on durvalumab after concurrent chemoradiotherapy in unresectable stage III, locally advanced, non-small cell lung cancer: analysis of patients enrolled in the French Early Access Program. Lung 200(1):95–105

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Doerr F et al (2022) Stage I and II small-cell lung cancer-new challenge for surgery. Lung 200(4):505–512

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Zhu W, Tan C, Zhang J (2022) Alveolar epithelial type 2 cell dysfunction in idiopathic pulmonary fibrosis. Lung 200(5):539–547

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Shao M et al (2022) Pathophysiological changes in rhesus monkeys with paraquat-induced pulmonary fibrosis. Lung 200(5):549–560

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Todd JL et al (2022) Association of circulating proteins with death or lung transplant in patients with idiopathic pulmonary fibrosis in the IPF-PRO registry cohort. Lung 200(1):11–18

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Kim HJ et al (2022) Clinical outcomes of patients with combined idiopathic pulmonary fibrosis and emphysema in the IPF-PRO registry. Lung 200(1):21–29

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Yang S et al (2022) Serum oncomarkers in patients with MPO-ANCA-positive vasculitis: diagnostic and prognostic predictive values for interstitial lung disease. Lung 200(3):331–338

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Park H et al (2022) Child interstitial lung disease in an infant with surfactant protein C dysfunction due to c. 202G>T variant (p. V68F). Lung 200(1):67–71

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RoyChoudhury A et al (2022) Survival by lung-transplantation preference in interstitial lung disease patients with severe pulmonary hypertension and high lung allocation score (correspondence). Lung 200(1):137–139

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Kalra SS et al (2022) Hypersensitivity pneumonitis with and without autoimmune features: a clinical comparative analysis. Lung 200(6):763–771

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Lim HF et al (2022) Shortened telomere length in sputum cells of bronchiectasis patients is associated with dysfunctional inflammatory pathways. Lung 200(3):401–407

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McGarvey LP, Birring SS, Morice AH et al (2022) Efficacy and safety of gefapixant, a P2X3 receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials. Lancet 399(10328):909–923. https://doi.org/10.1016/S0140-6736(21)02348-5

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Dicpinigaitis PV (2021) Coming soon: the first-ever drug(s) for refractory chronic cough (editorial). Lung 199(2):83–84

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Chung KF et al (2022) Tackling the neuropathic cough of idiopathic pulmonary fibrosis (IPF): more needs to be done. Lung 200(6):673–675

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Rudd M, Song W-J, Small PM (2022) The statistics of counting coughs: easy as 1,2,3? (editorial). Lung 200(5):531–537

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Schelfhout J et al (2022) Validation and meaningful change thresholds for an objective cough frequency measurement in chronic cough. Lung 200(6):717–724

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An J et al (2022) Cough presentation and cough-related healthcare utilization in tertiary care: analysis of routinely collected academic institutional database. Lung 200(4):431–439

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Song W-J, Yu C-J, Kang SH (2022) Cough characteristics and healthcare journeys of chronic cough patients in community-based populations in South Korea and Taiwan. Lung 200(6):725–736

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Kaneko H, Suzuki A, Horie J (2022) Effects of cough training and inspiratory muscle training on cough strength in older adults: a randomized controlled trial. Lung 200(1):49–57

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Nussbaum J et al (2022) A randomized, placebo-controlled study to investigate the safety, tolerability, and pharmacokinetics of 3 weeks of orally administered gefapixant in healthy younger and older adults. Lung 200(3):315–323

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Smith JA et al (2022) Improvements in objective and subjective measures of chronic cough with gefapixant: a pooled phase 3 efficacy analysis of predefined subgroups. Lung 200(4):423–429

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