Goldberg DS, McGee SJ (2011) Pain as a global public health priority. BMC Public Health 11:770. https://doi.org/10.1186/1471-2458-11-770
Swieboda P, Filip R, Prystupa A, Drozd M (2013) Assessment of pain: types, mechanism and treatment. Ann Agric Environ Med Spec 1:2–7
Falk S, Dickenson AH (2014) Pain and nociception: mechanisms of cancer-induced bone pain. J Clin Oncol 32:1647–1654. https://doi.org/10.1200/jco.2013.51.7219
Zylla D, Steele G, Gupta P (2017) A systematic review of the impact of pain on overall survival in patients with cancer. Support Care Cancer 25:1687–1698. https://doi.org/10.1007/s00520-017-3614-y
Coleman RE, Croucher PI, Padhani AR, Clézardin P, Chow E, Fallon M, Guise T, Colangeli S, Capanna R, Costa L (2020) Bone metastases. Nat Rev Dis Primers 6:83. https://doi.org/10.1038/s41572-020-00216-3
Coleman RE (2006) Clinical features of metastatic bone disease and risk of skeletalmorbidity. Clin Cancer Res 12:6243s-s6249. https://doi.org/10.1158/1078-0432.Ccr-06-0931
Cleeland CS, Body JJ, Stopeck A, von Moos R, Fallowfield L, Mathias SD, Patrick DL, Clemons M, Tonkin K, Masuda N, Lipton A, de Boer R, Salvagni S, Oliveira CT, Qian Y, Jiang Q, Dansey R, Braun A, Chung K (2013) Pain outcomes in patients with advanced breast cancer and bone metastases: results from a randomized, double-blind study of denosumab and zoledronic acid. Cancer 119:832–838. https://doi.org/10.1002/cncr.27789
Clézardin P, Coleman R, Puppo M, Ottewell P, Bonnelye E, Paycha F, Confavreux CB, Holen I (2021) Bone metastasis: mechanisms, therapies, and biomarkers. Physiol Rev 101:797–855. https://doi.org/10.1152/physrev.00012.2019
von Moos R, Costa L, Ripamonti CI, Niepel D, Santini D (2017) Improving quality of life in patients with advanced cancer: targeting metastatic bone pain. Eur J Cancer 71:80–94. https://doi.org/10.1016/j.ejca.2016.10.021
Halabi S, Vogelzang NJ, Kornblith AB, Ou SS, Kantoff PW, Dawson NA, Small EJ (2008) Pain predicts overall survival in men with metastatic castration-refractory prostate cancer. J Clin Oncol 26:2544–2549. https://doi.org/10.1200/jco.2007.15.0367
Coveler AL, Mizrahi J, Eastman B, Apisarnthanarax SJ, Dalal S, McNearney T, Pant S (2021) Pancreas cancer-associated pain management. Oncologist 26:e971–e982. https://doi.org/10.1002/onco.13796
Patrick DL, Ferketich SL, Frame PS, Harris JJ, Hendricks CB, Levin B, Link MP, Lustig C, McLaughlin J, Ried LD, Turrisi AT 3rd, Unützer J, Vernon SW (2003) National institutes of health state-of-the-science conference statement: symptom management in cancer: pain, depression, and fatigue, July 15–17, 2002. J Natl Cancer Inst 95:1110–1117. https://doi.org/10.1093/jnci/djg014
Staats PS, Hekmat H, Sauter P, Lillemoe K (2001) The effects of alcohol celiac plexus block, pain, and mood on longevity in patients with unresectable pancreatic cancer: a double-blind, randomized, placebo-controlled study. Pain Med 2:28–34. https://doi.org/10.1046/j.1526-4637.2001.002001028.x
Mantyh PW (2014) Bone cancer pain: from mechanism to therapy. Curr Opin Support Palliat Care 8:83–90. https://doi.org/10.1097/spc.0000000000000048
Ivanusic JJ (2017) Molecular mechanisms that contribute to bone marrow pain. Front Neurol 8:458. https://doi.org/10.3389/fneur.2017.00458
Liebig C, Ayala G, Wilks JA, Berger DH, Albo D (2009) Perineural invasion in cancer: a review of the literature. Cancer 115:3379–3391. https://doi.org/10.1002/cncr.24396
Bapat AA, Hostetter G, Von Hoff DD, Han H (2011) Perineural invasion and associated pain in pancreatic cancer. Nat Rev Cancer 11:695–707. https://doi.org/10.1038/nrc3131
Ivanusic JJ (2009) Size, neurochemistry, and segmental distribution of sensory neurons innervating the rat tibia. J Comp Neurol 517:276–283. https://doi.org/10.1002/cne.22160
Jung WC, Levesque JP, Ruitenberg MJ (2017) It takes nerve to fight back: the significance of neural innervation of the bone marrow and spleen for immune function. Semin Cell Dev Biol 61:60–70. https://doi.org/10.1016/j.semcdb.2016.08.010
Brazill JM, Beeve AT, Craft CS, Ivanusic JJ, Scheller EL (2019) Nerves in bone: evolving concepts in pain and anabolism. J Bone Miner Res 34:1393–1406. https://doi.org/10.1002/jbmr.3822
Wan QQ, Qin WP, Ma YX, Shen MJ, Li J, Zhang ZB, Chen JH, Tay FR, Niu LN, Jiao K (2021) Crosstalk between Bone and Nerves within Bone. Adv Sci (Weinh) 8:2003390. https://doi.org/10.1002/advs.202003390
Cooper RR (1968) Nerves in cortical bone. Science 160:327–328. https://doi.org/10.1126/science.160.3825.327
Serre CM, Farlay D, Delmas PD, Chenu C (1999) Evidence for a dense and intimate innervation of the bone tissue, including glutamate-containing fibers. Bone 25:623–629. https://doi.org/10.1016/s8756-3282(99)00215-x
Irie K, Hara-Irie F, Ozawa H, Yajima T (2002) Calcitonin gene-related peptide (CGRP)-containing nerve fibers in bone tissue and their involvement in bone remodeling. Microsc Res Tech 58:85–90. https://doi.org/10.1002/jemt.10122
Mach DB, Rogers SD, Sabino MC, Luger NM, Schwei MJ, Pomonis JD, Keyser CP, Clohisy DR, Adams DJ, O’Leary P, Mantyh PW (2002) Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur. Neuroscience 113:155–166. https://doi.org/10.1016/s0306-4522(02)00165-3
Fukuda T, Takeda S, Xu R, Ochi H, Sunamura S et al (2013) Sema3A regulates bone-mass accrual through sensory innervations. Nature 497:490–493. https://doi.org/10.1038/nature12115
Julius D, Basbaum AI (2001) Molecular mechanisms of nociception. Nature 413:203–210. https://doi.org/10.1038/35093019
Chartier SR, Mitchell SAT, Majuta LA, Mantyh PW (2018) The changing sensory and sympathetic innervation of the young, adult and aging mouse femur. Neuroscience 387:178–190. https://doi.org/10.1016/j.neuroscience.2018.01.047
Hiasa M, Okui T, Allette YM, Ripsch MS, Sun-Wada GH, Wakabayashi H, Roodman GD, White FA, Yoneda T (2017) Bone pain induced by multiple myeloma is reduced by targeting V-ATPase and ASIC3. Cancer Res 77:1283–1295. https://doi.org/10.1158/0008-5472.Can-15-3545
Wakabayashi H, Wakisaka S, Hiraga T, Hata K, Nishimura R, Tominaga M, Yoneda T (2018) Decreased sensory nerve excitation and bone pain associated with mouse Lewis lung cancer in TRPV1-deficient mice. J Bone Miner Metab 36:274–285. https://doi.org/10.1007/s00774-017-0842-7
Magnon C, Hall SJ, Lin J, Xue X, Gerber L, Freedland SJ, Frenette PS (2013) Autonomic nerve development contributes to prostate cancer progression. Science 341:1236361. https://doi.org/10.1126/science.1236361
Jobling P, Pundavela J, Oliveira SM, Roselli S, Walker MM, Hondermarck H (2015) Nerve-cancer cell cross-talk: a novel promoter of tumor progression. Cancer Res 75:1777–1781. https://doi.org/10.1158/0008-5472.Can-14-3180
Elefteriou F (2018) Impact of the autonomic nervous system on the skeleton. Physiol Rev 98:1083–1112. https://doi.org/10.1152/physrev.00014.2017
Zahalka AH, Frenette PS (2020) Nerves in cancer. Nat Rev Cancer 20:143–157. https://doi.org/10.1038/s41568-019-0237-2
Lorenz MR, Brazill JM, Beeve AT, Shen I, Scheller EL (2021) A neuroskeletal atlas: spatial mapping and contextualization of axon subtypes innervating the long bones of C3H and B6 mice. J Bone Miner Res 36:1012–1025. https://doi.org/10.1002/jbmr.4273
Mercadante S (1997) Malignant bone pain: pathophysiology and treatment. Pain 69:1–18. https://doi.org/10.1016/s0304-3959(96)03267-8
Zajączkowska R, Kocot-Kępska M, Leppert W, Wordliczek J (2019) Bone pain in cancer patients: mechanisms and current treatment. Int J Mol Sci. https://doi.org/10.3390/ijms20236047
Silverman DA, Martinez VK, Dougherty PM, Myers JN, Calin GA, Amit M (2021) Cancer-associated neurogenesis and nerve-cancer cross-talk. Cancer Res 81:1431–1440. https://doi.org/10.1158/0008-5472.Can-20-2793
Okui T, Hiasa M, Ryumon S, Ono K, Kunisada Y, Ibaragi S, Sasaki A, Roodman GD, White FA, Yoneda T (2021) The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone. J Bone Oncol 26:100330. https://doi.org/10.1016/j.jbo.2020.100330
Jimenez-Andrade JM, Bloom AP, Stake JI, Mantyh WG, Taylor RN, Freeman KT, Ghilardi JR, Kuskowski MA, Mantyh PW (2010) Pathological sprouting of adult nociceptors in chronic prostate cancer-induced bone pain. J Neurosci 30:14649–14656. https://doi.org/10.1523/jneurosci.3300-10.2010
March B, Faulkner S, Jobling P, Steigler A, Blatt A, Denham J, Hondermarck H (2020) Tumour innervation and neurosignalling in prostate cancer. Nat Rev Urol 17:119–130. https://doi.org/10.1038/s41585-019-0274-3
Maes C, Carmeliet G, Schipani E (2012) Hypoxia-driven pathways in bone development, regeneration and disease. Nat Rev Rheumatol 8:358–366. https://doi.org/10.1038/nrrheum.2012.36
Simon MC, Keith B (2008) The role of oxygen availability in embryonic development and stem cell function. Nat Rev Mol Cell Biol 9:285–296. https://doi.org/10.1038/nrm2354
Liberti MV, Locasale JW (2016) The Warburg Effect: how does it benefit cancer cells? Trends Biochem Sci 41:211–218. https://doi.org/10.1016/j.tibs.2015.12.001
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