The Presence of Typical “BRAFV600E-Like” Atypia in Papillary Thyroid Carcinoma is Highly Specific for the Presence of the BRAFV600E Mutation

Agrawal N, Akbani R, Aksoy BA, Ally A, Arachchi H, et al Integrated genomic characterization of papillary thyroid carcinoma. Cell 2014;159(3):676-90

Article  Google Scholar 

WHO Classification of Tumours Editorial Board 2022, WHO Classification of Tumours of Endocrine Organs. Vol 10. 5th ed. Lyon, France: WHO/IARC Press

Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho-Simões M, Tallini G, Mete O. Overview of the 2022 WHO Classification of Thyroid Neoplasms. Endocrine pathology 2022;33(1):27-63.

Article  Google Scholar 

Tallini G, Tuttle RM, Ghossein RA. The History of the Follicular Variant of Papillary Thyroid Carcinoma. J Clin Endocrinol Metab. 2017 Jan 1;102(1):15-22.

Article  Google Scholar 

Virk RK, Theoharis CG, Prasad A, Chhieng D, Prasad ML. Morphology predicts BRAF (V600E) mutation in papillary thyroid carcinoma: an interobserver reproducibility study. Virchows Arch. 2014 Apr;464(4):435-42

Article  CAS  Google Scholar 

Finkelstein A, Levy GH, Hui P, Prasad A, Virk R, Chhieng DC, Carling T, Roman SA, Sosa JA, Udelsman R, Theoharis CG, Prasad ML. Papillary thyroid carcinomas with and without BRAF V600E mutations are morphologically distinct. Histopathology. 2012 Jun;60(7):1052-9

Article  Google Scholar 

Schwertheim S, Theurer S, Jastrow H, Herold T, Ting S, Westerwick D, Bertram S, Schaefer CM, Kälsch J, Baba HA, Schmid KW. New insights into intranuclear inclusions in thyroid carcinoma: Association with autophagy and with BRAFV600E mutation. PLoS One. 2019 Dec 16;14(12):e0226199.

Article  CAS  Google Scholar 

Rossi ED, Martini M, Bizzarro T, Schmitt F, Longatto-Filho A, Larocca LM. Somatic mutations in solid tumors: a spectrum at the service of diagnostic armamentarium or an indecipherable puzzle? The morphological eyes looking for BRAF and somatic molecular detections on cyto-histological samples. Oncotarget. 2017 Jan 10;8(2):3746-3760

Article  Google Scholar 

Virk RK, Van Dyke AL, Finkelstein A, Prasad A, Gibson J, Hui P, Theoharis CG, Carling T, Roman SA, Sosa JA, Udelsman R, Prasad ML. BRAFV600E mutation in papillary thyroid microcarcinoma: a genotype-phenotype correlation. Mod Pathol. 2013 Jan;26(1):62-70.

Article  CAS  Google Scholar 

Bernstein J, Virk RK, Hui P, Prasad A, Westra WH, Tallini G, Adeniran AJ, Udelsman R, Sasaki CT, Roman SA, Sosa JA, Prasad ML. Tall cell variant of papillary thyroid microcarcinoma: clinicopathologic features with BRAF(V600E) mutational analysis. Thyroid. 2013 Dec;23(12):1525-31.

Article  CAS  Google Scholar 

Pillai S, Gopalan V, Smith RA, Lam AK. Diffuse sclerosing variant of papillary thyroid carcinoma--an update of its clinicopathological features and molecular biology. Crit Rev Oncol Hematol. 2015 Apr;94(1):64-73

Article  Google Scholar 

Dolezal JM, Trzcinska A, Liao CY, Kochanny S, Blair E, Agrawal N, Keutgen XM, Angelos P, Cipriani NA, Pearson AT. Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2021;34(5):862–74.

Jung CK, Bychkov A, Song DE, Kim JH, Zhu Y, Liu Z, Keelawat S, Lai CR, Hirokawa M, Kameyama K, Kakudo K. Molecular Correlates and Nuclear Features of Encapsulated Follicular-Patterned Thyroid Neoplasms. Endocrinology and metabolism (Seoul, Korea) 2021;36(1):123-33

Article  CAS  Google Scholar 

Macerola E, Poma AM, Vignali P, Basolo A, Ugolini C, Torregrossa L, Santini F, Basolo F. Molecular Genetics of Follicular-Derived Thyroid Cancer. Cancers 2021;13(5):1139

Article  CAS  Google Scholar 

Kakudo K. Different Threshold of Malignancy for RAS-like Thyroid Tumors Causes Significant Differences in Thyroid Nodule Practice. Cancers 2022;14(3):812.

Article  CAS  Google Scholar 

Cho U, Mete O, Kim MH, Bae JS, Jung CK. Molecular correlates and rate of lymph node metastasis of non-invasive follicular thyroid neoplasm with papillary-like nuclear features and invasive follicular variant papillary thyroid carcinoma: the impact of rigid criteria to distinguish non-invasive follicular thyroid neoplasm with papillary-like nuclear features. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2017;30(6):810–25.

Gan X, Shen F, Deng X, Feng J, Lu J, Cai W, Peng L, Zheng W, Wang W, Huang P, Chen Z, Guo M, Xu B. Prognostic implications of the BRAF-V600E mutation in papillary thyroid carcinoma based on a new cut-off age stratification. Oncol Lett. 2020 Jan;19(1):631-640.

CAS  Google Scholar 

Xing M, Westra WH, Tufano RP, Cohen Y, Rosenbaum E, Rhoden KJ, Carson KA, Vasko V, Larin A, Tallini G, Tolaney S, Holt EH, Hui P, Umbricht CB, Basaria S, Ewertz M, Tufaro AP, Califano JA, Ringel MD, Zeiger MA, Sidransky D, Ladenson PW. BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer. J Clin Endocrinol Metab. 2005 Dec;90(12):6373-9

Article  CAS  Google Scholar 

Kim TY, Kim WB, Rhee YS, Song JY, Kim JM, Gong G, Lee S, Kim SY, Kim SC, Hong SJ, Shong YK. The BRAF mutation is useful for prediction of clinical recurrence in low-risk patients with conventional papillary thyroid carcinoma. Clin Endocrinol (Oxf). 2006 Sep;65(3):364-8.

Article  CAS  Google Scholar 

Ahn D, Park JS, Sohn JH, Kim JH, Park SK, Seo AN, Park JY. BRAFV600E mutation does not serve as a prognostic factor in Korean patients with papillary thyroid carcinoma. Auris Nasus Larynx. 2012 Apr;39(2):198-203

Article  Google Scholar 

Scheffel RS, de Cristo AP, Romitti M, Vargas CVF, Ceolin L, Zanella AB, Dora JM, Maia AL. The BRAFV600E mutation analysis and risk stratification in papillary thyroid carcinoma. Arch Endocrinol Metab. 2021 May 18;64(6):751-757

Google Scholar 

Fraser S, Go C, Aniss A, Sidhu S, Delbridge L, Learoyd D, Clifton-Bligh R, Tacon L, Tsang V, Robinson B, Gill AJ, Sywak M. BRAF(V600E) Mutation is Associated with Decreased Disease-Free Survival in Papillary Thyroid Cancer. World J Surg. 2016 Jul;40(7):1618-24.

Article  CAS  Google Scholar 

Bullock M, O'Neill C, Chou A, Clarkson A, Dodds T, Toon C, Sywak M, Sidhu SB, Delbridge LW, Robinson BG, Learoyd DL, Capper D, von Deimling A, Clifton-Bligh RJ, Gill AJ. Utilization of a MAB for BRAF(V600E) detection in papillary thyroid carcinoma. Endocr Relat Cancer. 2012 Nov 9;19(6):779-84.

Article  CAS  Google Scholar 

Choden S, Keelawat S, Jung CK, Bychkov A. An affordable immunohistochemical approach to estimate the prevalence of BRAFV600E in large cohort studies-establishing the baseline rate of BRAF mutation in an institutional series of papillary thyroid carcinoma from Thailand. Gland Surg. 2020 Oct;9(5):1867-1877.

Article  Google Scholar 

Ilie MI, Lassalle S, Long-Mira E, Bonnetaud C, Bordone O, Lespinet V, Lamy A, Sabourin JC, Haudebourg J, Butori C, Guevara N, Peyrottes I, Sadoul JL, Bozec A, Santini J, Capper D, von Deimling A, Emile JF, Hofman V, Hofman P. Diagnostic value of immunohistochemistry for the detection of the BRAF(V600E) mutation in papillary thyroid carcinoma: comparative analysis with three DNA-based assays. Thyroid. 2014 May;24(5):858-66.

Article  CAS  Google Scholar 

Parker KG, White MG, Cipriani NA. Comparison of Molecular Methods and BRAF Immunohistochemistry (VE1 Clone) for the Detection of BRAF V600E Mutation in Papillary Thyroid Carcinoma: A Meta-Analysis. Head Neck Pathol. 2020 Dec;14(4):1067-1079.

Article  Google Scholar 

Shi X, Liu R, Basolo F, Giannini R, Shen X, Teng D, Guan H, Shan Z, Teng W, Musholt TJ, Al-Kuraya K, Fugazzola L, Colombo C, Kebebew E, Jarzab B, Czarniecka A, Bendlova B, Sykorova V, Sobrinho-Simões M, Soares P, Shong YK, Kim TY, Cheng S, Asa SL, Viola D, Elisei R, Yip L, Mian C, Vianello F, Wang Y, Zhao S, Oler G, Cerutti JM, Puxeddu E, Qu S, Wei Q, Xu H, O'Neill CJ, Sywak MS, Clifton-Bligh R, Lam AK, Riesco-Eizaguirre G, Santisteban P, Yu H, Tallini G, Holt EH, Vasko V, Xing M. Differential Clinicopathological Risk and Prognosis of Major Papillary Thyroid Cancer Variants. J Clin Endocrinol Metab. 2016 Jan;101(1):264-74.

Article  CAS  Google Scholar 

Cheng S, Serra S, Mercado M, Ezzat S, Asa SL. A high-throughput proteomic approach provides distinct signatures for thyroid cancer behavior. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 2011 Apr;17(8):2385-2394.

Article  CAS  Google Scholar 

Tsang V, Gill A, Gild M, Lurie B, Blumer L, Siddall R, Clifton-Bligh R, Robinson B. Selpercatinib Treatment of RET-Mutated Thyroid Cancers Is Associated with Gastrointestinal Adverse Effects. The Journal of clinical endocrinology and metabolism 2022;107(9):e3824-e3829.

Article  Google Scholar 

Angell TE. RAS-positive thyroid nodules. Curr Opin Endocrinol Diabetes Obes. 2017 Oct;24(5):372-376.

Article  CAS  Google Scholar 

Chou A, Bullock S, Toon CW, Clarkson A, Sioson L, Farzin M, Cussigh C, Aniss A, O'Neill C, Watson N, Clifton-Bligh RJ, Learoyd DL, Robinson BG, Selinger CI, Delbridge LW, Sidhu SB, O'Toole SA, Sywak M, Gill AJ. A detailed clinicopathologic study of ALK-translocated papillary thyroid carcinoma. Am J Surg Pathol. 2015 May;39(5):652–9.

Nozaki Y, Yamamoto H, Iwasaki T, Sato M, Jiromaru R, Hongo T, Yasumatsu R, Oda Y. Clinicopathological features and immunohistochemical utility of NTRK-, ALK-, and ROS1-rearranged papillary thyroid carcinomas and anaplastic thyroid carcinomas. Hum Pathol. 2020 Dec;106:82-92.

Article  CAS  Google Scholar 

Esce AR, Redemann JP, Sanchez AC, Olson GT, Hanson JA, Agarwal S, Boyd NH, Martin DR. Predicting nodal metastases in papillary thyroid carcinoma using artificial intelligence. Am J Surg. 2021 Nov;222(5):952-958.

Article  Google Scholar 

Yoon J, Lee E, Koo JS, Yoon JH, Nam KH, Lee J, Jo YS, Moon HJ, Park VY, Kwak JY. Artificial intelligence to predict the BRAFV600E mutation in patients with thyroid cancer. PLoS One. 2020 Nov 25;15(11):e0242806.

Article  CAS  Google Scholar 

Baloch ZW, LiVolsi VA. Pathologic diagnosis of papillary thyroid carcinoma: today and tomorrow. Expert Rev Mol Diagn. 2005 Jul;5(4):573-84.

Article  CAS  Google Scholar 

留言 (0)

沒有登入
gif