We thank Dr. Ramin Azizimalamiri and Dr. Hamid Galehdari for their help in clinical and molecular characterization. YJC acknowledges the European Research Council (786142-E-T1IFNs), and a state subsidy managed by the National Research Agency (France) under the “Investments for the Future” program bearing the reference ANR-10-IAHU-01.

for the AGS Group Luis I Gonzalez-Granado1, Giulia Please check if the ''for the AGS Group'' is presented and captured correctly.Coarelli2,3, Lucie Pierron2,3, Isabelle Maystadt4,5, Matias Wagner6,7,8, Mina Zamani9,10, Saeid Sadeghian11, Clémence David12, Gillian I Rice.13

1Unidad de Inmunodeficiencias, Pediatría, Instituto de Investigación Hospital 12 de Octubre, Facultad de Medicina, Universidad Complutense, Madrid, Spain.

2Sorbonne Université, Paris Brain Institute—ICM, Inserm, CNRS, APHP, Paris, France.

3Department of Genetics, Neurogene National Reference Centre for Rare Diseases, Pitié-Salpêtrière University Hospital, Assistance Publique, Hôpitaux de Paris, Paris, France.

4Centre de Génétique Humaine, Institut de Pathologie et de Génétique, Gosselies, Belgium.

5Faculté de Médecine, URPhyM, UNamur, Namur, Belgium.

6Institute of Human Genetics, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.

7Institute for Neurogenomics, Helmholtz Zentrum München, Neuherberg, Germany.

8Division of Pediatric Neurology, Developmental Neurology and Social Pediatrics, Dr. von Hauner Children’s Hospital, Munich, Germany.

9Department of Biology, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran.

10Narges Medical Genetics and Prenatal Diagnosis Laboratory, East Mihan Ave, Kianpars, Ahvaz, Iran.

11Department of Pediatric Neurology, Golestan Medical, Educational, and Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

12Laboratory of Neurogenetics and Neuroinflammation, Institut Imagine, Université de Paris, Paris, France.

13Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.