Olfactory Dysfunction in Mental Illness

•• Hasegawa Y, Ma M, Sawa A, Lane AP, Kamiya A. Olfactory impairment in psychiatric disorders: does nasal inflammation impact disease psychophysiology? Transl Psych. 2022; 12: 314. COMMENT: Review about the role of nasal inflammation in the pathophysiology of psychiatric disorders.

•• Croy I, Hummel T. Olfaction as a marker for depression. J Neurol. 2017;264:631–8. COMMENT: Loss of smell as a clinical symptom and marker for depression.

Article  CAS  Google Scholar 

Moberg PJ, Kamath V, Marchetto DM, Calkins ME, Doty RL, Hahn CG, Borgmann-Winter KE, Kohler CG, Gur RE, Turetsky BI. Meta-analysis of olfactory function in schizophrenia, first-degree family members, and youths at risk for psychosis. Schizophr Bull. 2014;40:50–9.

Article  Google Scholar 

•• Pinto JM, Wroblewski KE, Kern DW, Schumm LP, McClintock MK. Olfactory dysfunction predicts 5-year mortality in older adults. PLoS ONE. 2014;9: e107541. COMMENT: Relationship between olfactory dysfunction and an increased mortality rate.

Article  Google Scholar 

Choi JS, Jang SS, Kim J, Hur K, Ference E, Wrobel B. Association between olfactory dysfunction and mortality in US adults. JAMA Otolaryngol Head Neck Surg. 2021;147:49–55.

Article  Google Scholar 

Henry C, Meyrel M, Bigot M, Alonso M, Lledo PM, Dárgel AA. Can olfactory dysfunction be a marker of trait of states of bipolar disorders. J Affect Dis. 2020;266:498–502.

Article  Google Scholar 

Bhattarai JP, Etyemez S, Jaaro-Peled H, Janke E, Leon Tolosa UD, Kamiya A, Gottfried JA, Sawa A, Ma M. Olfactory modulation of the medial prefrontal cortex circuitry: implications for social cognition. Semin Cell Dev Biol. 2022;129:31–9.

Article  Google Scholar 

El-Hage W. Olfaction as a marker for psychiatric and neurological diseases. Brain Sci. 2021;12:23.

Article  Google Scholar 

Chen X, Xu J, Li B, Guo W, Zhang J, Hu J. Olfactory impairment in first-episode schizophrenia: a case-control study, and sex dimorphism in the relationship between olfactory impairment and psychotic symptoms. BMC Psychiatry. 2018;18:199.

Article  Google Scholar 

Su CY, Menuz K, Carlson JR. Olfactory perception: receptors, cells and circuits. Cell. 2009;129:45–59.

Article  Google Scholar 

Wilson DA, Sullivan RM. Cortical processing of odor subjects. Neuron. 2011;72:506–19.

Article  CAS  Google Scholar 

Misiak M, Hipolito MM, Ressom HW, Obisesan TO, Manaye KF, Nwlia EA. Apo E4 alleles and impaired olfaction as predictors of Alzheimer’s Disease. Clin Exp Psychol. 2017;3:169.

Article  Google Scholar 

Imamura F, Ito A, LaFever BJ. Subpopulations of projection neurons in the olfactory bulb. Front Neural Circuits. 2020;14: 561822.

Article  Google Scholar 

Doty RL, Philip S, Reddy K, Kerr KL. Influences of antihypertensive and antihyperlipidemic drugs on the senses of taste and smell: a review. J Hypertens. 2003;21:1805–13.

Article  CAS  Google Scholar 

Kanaya K, Kondo K, Suzukawa K, Sakamoto T, Kikuta S, Okada K, Yamasoba T. Innate immune responses and neuroepithelial degeneration and regeneration in the mouse olfactory mucosa induced by intranasal administration of Poly (I:C). Cell Tissue Res. 2014;357:279–99.

Article  CAS  Google Scholar 

Attems J, Walker L, Jellinger KA. Olfaction and aging: a mini-review. Gerontology. 2015;61:485–90.

Article  CAS  Google Scholar 

Nagayama S, Takakhashi YK, Yoshihara Y, Mori K. Mitral and tufted cells differ in the decoding manner of odor maps in the rat olfactory bulb. J Neurophysiol. 2004;91:2532–40.

Article  Google Scholar 

Mullol J, Alobid I, Mariño-Sánchez F, Quintó L, de Haro J Bernal-Sprekelsen M, Valero A, Picado C, Marin C. Furthering the understanding of olfaction, prevalence of loss of smell and risk factors: a population-based survey (OLFACAT study). MBJ Open. 2012; 2: e001256.

Taalman H, Wallace C, Milev R. Olfactory functioning and depression: a systemic review. Front Psychiatry. 2017;8:190.

Article  Google Scholar 

Malaspina D, Coleman E. Olfaction and social-drive in schizophrenia. Arch Gen Psychiatry. 2003;60:578–84.

Article  Google Scholar 

•• Moberg PJ, Arnold SE, Doty RL, Gur RE, Balderston CC, Roalf DR, Gur RC, Kohler CG, Kanes SJ, Siegel SJ, Turetsky BI. Olfactory functioning in schizophrenia: relationship to clinical neuropsychological, and volumetric MRI measures. J Clin Exp Neuropsychol. 2006;28:1444–61. COMMENT: Olfactory dysfunction in schizophrenia and central nervous system structural alterations.

Article  Google Scholar 

Clepce M, Gossler A, Reich K, Kornhuber J, Thuerauf N. The relation between, depression, anhedonia and olfactory hedonic estimates-a pilot study in major depression. Neurosci Lett. 2010;471:139–43.

Article  CAS  Google Scholar 

Ishizuka K, Tajinda K, Colantuoni C, Morita M, Winicki J, Le C, Lin S, Schretlen D, Sawa A, Cascella NG. Negative symptoms of schizophrenia correlate with impairment on the University of Pennsylvania smell identification test. Neurosci Res. 2010;66:106–10.

Article  Google Scholar 

Croy I, Symmank A, Schellong J, Hummel C, Gerber J, Joraschky P, Hummel T. Olfaction as a marker for depression in humans. J Affect Disord. 2014;160:80–6.

Article  Google Scholar 

Chen X, Guo W, Yu L, Luo D, Xie L, Xu J. Association between anxious symptom severity and olfactory impairment in young adults with generalized anxiety disorder: a case-control study. Neuropsychiatr Dis Treat. 2021;17:2977–2883.

Article  Google Scholar 

Clepce M, Reich K, Gossler A, Kornhuber J, Thuerauf N. Olfactory abnormalities in anxiety disorders. Neurosci Lett. 2012;511:43–6.

Article  CAS  Google Scholar 

Good KP, Sullivan RK. Olfactory function in psychotic disorders: insights from neuroimaging studies. World J Psychiatry. 2015;5:210–21.

Article  Google Scholar 

Milad MR, Rauch SL. The role of the orbitofrontal cortex in anxiety disorders. Ann NY Acad Sci. 2010;1121:546–61.

Article  Google Scholar 

Nguyen AD, Shenton ME, Levitt JJ. Olfactory dysfunction in schizophrenia: a review of neuroanatomy and psychophysiological measurements. Harv Rev Psychiatry. 2010;18:279–92.

Article  Google Scholar 

Houghton DC, Howard SK, Uhde TW, Paquet C, Schlosser RJ, Cortese RM. Odor sensitivity impairment: a behavioral marker for psychological distress? CNS Spectr. 2019;24:404–12.

Article  Google Scholar 

Houghton DC, Stein DJ, Cortese BM. Review: Exteroceptive sensory abnormalities in childhood and adolescent anxiety and obsessive-compulsive disorder: a critical review. J Am Acad Child Adolesc Psychiatry. 2020;59:78–87.

Article  Google Scholar 

•• Cortese BM, Uhde TW, Schumann AY, McTeague LM, Sege CT, Calhoun CD, Danielson CK. Anxiety-related shifts in smell function in children and adolescents. Chem Senses. 2021; 46: bjab051. COMMENT: Shifts in olfactory function in anxiety.

Cortese BM, Schumann AY, Howell AN, McConnell PA, Yang QX, Uhde TW. Preliminary evidence for differential olfactory and trigeminal processing in combat veterans with and without PTSD. Neuroimage Clin. 2018;17:378–87.

Article  Google Scholar 

La Buisonnière-Ariza V, Lepore F, Kojok KM, Frasnelli J. Increased odor detection speed in highly anxious healthy adults. Chem Senses. 2013;38:577–84.

Article  Google Scholar 

Krusemark EA, Li W. Enhanced olfactory sensory perception of threat in anxiety: an event-related fMRI study. Chemosens Percept. 2012;5:37–45.

Article  Google Scholar 

Galliot E, Laurent L, Hacquemand R, Purié G, Millot JL. Fear-like behavioral responses in mice in different odorant environments: trigeminal versus olfactory mediation under low doses. Behav Processes. 2012;90:161–6.

Article  Google Scholar 

Burón E, Bulbena A, Bulbena-Cabré A. Olfactory functioning in panic disorder. J Affect Disord. 2015;175:292–8.

Article  Google Scholar 

Kamath V, Paksarian D, Cui L, Moberg PJ, Turetsky BI, Merikangas KR. Olfactory processing in bipolar disorder, major depression, and anxiety. Bipolar Disord. 2018;20:547–55.

Article  Google Scholar 

Athanassi A, Doncel RD, Bath KG, Madairon N. Relationship between depression and olfactory sensory function: a review. Chem Senses. 2021;46:1–12.

Article  Google Scholar 

Dudine L, Canaletti C, Giudici F, Lunardelli A, Abram G, Santini I, Baroni V, Paris M, Peavento V, Manganotti P, Ronchese F, Gregoretti B, Negro C. Investigation on the loss of taste and smell and consequent psychological effects: a cross-sectional study on healthcare workers who contracted the COVID-19 infection. Front Public Health. 2021;9: 666442.

Article  Google Scholar 

•• Negoias S, Croy I, Gerber J, Puschmann S, Petrowski K, Joraschky P, Hummel T. Reduced olfactory bulb volume and olfactory sensitivity in patients with acute major depression. Neuroscience. 2010;169:415–21. COMMENT: Description of the reduction of olfactory bulbs and its association with olfactory function impairment and depression.

Article  CAS  Google Scholar 

Temmel AFP, Quint Ch, Schickinger-Fischer B, Klimek L, Stoller E, Hummel T. Characteristics of olfactory disorders in relation to major causes of olfactory loss. Arch Otolaryngol Head Neck Surg. 2002;128:635–41.

Article  Google Scholar 

Croy I, Nordin S, Hummel T. Olfactory disorders and quality of life-an updated review. Chem Senses. 2014;29:185–94.

Article  Google Scholar 

Lombion-Pouthier S, Vandel P, Nezelof S, Haffen E, Millot JL. Odor perception in patients with mood disorders. J Affect Disord. 2006;90:187–91.

Article  Google Scholar 

Kazour F, Richa S, Char AC, Surget A, Elhage W, Atanasova B. Olfactory markers for depression: differences between bipolar and unipolar patients. PLoS ONE. 2020;15: e0237565.

Article  CAS  Google Scholar 

Pause BM, Miranda A, Göder R, Aldenhoff JB, Ferstl R. Reduced olfactory performance in patients with major depression. J Psychiatr Res. 2001;35:271–7.

Article  CAS  Google Scholar 

Kohli P, Soler ZM, Nguyen SA, Muus JS, Schlosser RJ. The association between olfaction and depression: a systematic review. Chem Sense, s. 2016;41:479–86.

Article  Google Scholar 

Khil I, Rahe C, Wellmann J, Baune BT, Wersching H, Berger K. Association between major depressive disorder and odor identification impairment. J Affect Disord. 2016;203:332–8.

Article  Google Scholar 

Marine N, Boriana A. Olfactory markers of depression and Alzheimer’s disease. Neurosci Biobehav Rev. 2014;45:262–70.

Article  CAS  Google Scholar 

Chen B, Klarmann R, Israel M, Ning Y, Colle R, Hummel T. Difference of olfactory deficit in patients with acute episode of schizophrenia and major depressive episode. Schizo Res. 2019;212:99–106.

Article  Google Scholar 

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